Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Patients who undergo gastric bypass less likely to have risk of heart attack and stroke

New research from the Cleveland Clinic shows most patients with diabetes and obesity who undergo gastric bypass not only experience remission of their diabetes and lose significant weight, but they also reduce their risk of having a heart attack by 40 percent and their risk for suffering a stroke by 42 percent, over a 10-year time horizon.

16 Nov 2013

MGH investigators identify molecule that plays key role in the breakdown of kidney filter

One of the most devastating side effects of diabetes is kidney failure, and one of the earliest signs of kidney damage is a disruption of the organ's filtering capacity. Diabetes patients who develop kidney failure must go on dialysis, seriously limiting their quality of life and placing them at significantly increased risk of death. The incidence of kidney disease is increasing with rising rates of obesity-associated type 2 diabetes, but very little progress has been made towards protecting the kidney's filter barrier during the past 50 years.

16 Nov 2013

Satellite Healthcare, NKF partner to sponsor free Community Kidney Disease Symposium

Satellite Healthcare, one of the nation's first and leading not-for-profit providers of kidney dialysis services and a major sponsor of kidney research, is proud to announce that it has partnered with the National Kidney Foundation to sponsor NKF's free Community Kidney Disease Symposium this Saturday, November 16th in Stockton, California.

16 Nov 2013

OPKO Health completes patient enrollment in first phase 3 trial of Rayaldy for SHPT treatment

OPKO Health, Inc., has completed patient recruitment in the first phase 3 trial of Rayaldy to treat patients with secondary hyperparathyroidism, stage 3 or 4 chronic kidney disease and vitamin D insufficiency.

16 Nov 2013

Gastric bypass dramatically improves multiple cardiovascular risk factors in the long term

15 Nov 2013

Skeletal problems now added to list of diabetes complications

The list of complications from type 2 diabetes is long: vascular and heart disease, eye problems, nerve damage, kidney disease, hearing problems and Alzheimer's disease. Physicians have long thought of osteoporosis as another outcome. Based on a Mayo Clinic study published in the Journal of Bone and Mineral Research, that's confirmed: You can definitely add skeletal problems to that list.

14 Nov 2013

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

FibroGen, Inc. (FibroGen), today announced that data from a China-based Phase 2 study of roxadustat (FG-4592), a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD), were presented in an oral session at the 2013 American Society of Nephrology (ASN) Kidney Week in Atlanta, Georgia.

13 Nov 2013

African Americans with APOL1 gene variant experience faster progression of CKD

A large study co-authored by Penn Medicine published this week in the New England Journal of Medicine found that African Americans with the APOL1 gene variant experience faster progression of chronic kidney disease and have a significantly increased risk of kidney failure, regardless of their diabetes status.

13 Nov 2013

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that it has filed an investigational new drug application with the US Food and Drug Administration to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia in pre-dialysis patients with chronic kidney disease.

12 Nov 2013

Treatment with rheumatoid arthritis drug saved transplanted kidney and achieved remission

A drug approved for the treatment of rheumatoid arthritis may also turn out to be the first targeted therapy for one of the most common forms of kidney disease, a condition that almost inevitably leads to kidney failure.

11 Nov 2013

Genetic factors put African Americans with CKD at greater risk for end-stage renal disease

Genetic factors in African Americans with chronic kidney disease put them at a greater risk for end-stage renal disease compared to white Americans, according to a new study released today in the New England Journal of Medicine.

11 Nov 2013

New evidence shows particulate matter exposure associated with kidney damage

Many first responders working at Ground Zero following the 9/11 tragedy were exposed to cement dust, smoke, glass fibers, and heavy metals. Exposure to high levels of such particulate matter caused significant damage to first responders' kidneys, according to research presented at ASN Kidney Week 2013 November 9 at the Georgia World Congress Center in Atlanta, GA.

11 Nov 2013

Triferic drug is effective in preventing iron deficiency in patients with chronic kidney disease

Doctors at the North Shore-LIJ Health System on Saturday will present late-breaking data showing that an investigational drug Triferic is well tolerated and effective in treating iron deficiency in patients with chronic kidney disease undergoing dialysis.

11 Nov 2013

Recent studies suggest that controlling dietary acid intake may help improve kidney health

Three new studies suggest that controlling dietary acid intake could help improve kidney health. Results of these studies will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

11 Nov 2013

Genetic variations in African Americans with kidney disease contribute to rapid decline in kidney function

New research provides direct evidence that genetic variations in some African Americans with chronic kidney disease contribute to a more rapid decline in kidney function compared with white Americans.

10 Nov 2013

EKF Diagnostics to introduce upgraded POC analyzer and new sTNFr1 test kit at Medica 2013

EKF, announces it will be premiering two novel diagnostic tests at Medica 2013, 20th to 23rd November, Düsseldorf, Germany.

From EKF Diagnostics 8 Nov 2013

New coverage gaps, cost issues spur health law worries

News outlets look at the nuts and bolts of the health law's implementation, including a worry that coverage gaps will persist for some vulnerable people, as well as how the government pays for insurance subsidies and why some premium costs increase under the health law.

8 Nov 2013

Increased consumption of vegetable protein linked with prolonged survival among kidney disease patients

Increased consumption of vegetable protein was linked with prolonged survival among kidney disease patients in a new a study. The findings will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

8 Nov 2013

NIDDK director to receive Outstanding Achievement Award from NKF

The National Kidney Foundation will honor Dr. Griffin P. Rodgers, Director of the National Institute of Diabetes and Digestive and Kidney Diseases, one of the National Institutes of Health, for his commitment to bettering the lives of patients and raising awareness of chronic kidney disease.

7 Nov 2013

Simple urine test can help identify disease risks in young type 1 diabetes patients

Using a simple urine test, researchers can now identify young people with type 1 diabetes at risk of heart and kidney disease. The new research, funded by JDRF, Diabetes UK, and the British Heart Foundation, was published today, 06 November, in the journal Diabetes Care.

7 Nov 2013

Nephropathy News and Research

Further Reading

Patients who undergo gastric bypass less likely to have risk of heart attack and stroke

MGH investigators identify molecule that plays key role in the breakdown of kidney filter

Satellite Healthcare, NKF partner to sponsor free Community Kidney Disease Symposium

OPKO Health completes patient enrollment in first phase 3 trial of Rayaldy for SHPT treatment

Gastric bypass dramatically improves multiple cardiovascular risk factors in the long term

Skeletal problems now added to list of diabetes complications

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

African Americans with APOL1 gene variant experience faster progression of CKD

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

Treatment with rheumatoid arthritis drug saved transplanted kidney and achieved remission

Genetic factors put African Americans with CKD at greater risk for end-stage renal disease

New evidence shows particulate matter exposure associated with kidney damage

Triferic drug is effective in preventing iron deficiency in patients with chronic kidney disease

Recent studies suggest that controlling dietary acid intake may help improve kidney health

Genetic variations in African Americans with kidney disease contribute to rapid decline in kidney function

EKF Diagnostics to introduce upgraded POC analyzer and new sTNFr1 test kit at Medica 2013

New coverage gaps, cost issues spur health law worries

Increased consumption of vegetable protein linked with prolonged survival among kidney disease patients

NIDDK director to receive Outstanding Achievement Award from NKF

Simple urine test can help identify disease risks in young type 1 diabetes patients

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