Pathology News and Research

RSS

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

A new blood test could improve how Alzheimer’s disease is diagnosed

The blood test for eMTBR-tau243 shows strong correlation with tau pathology, enhancing Alzheimer's diagnosis and monitoring cognitive decline effectively.

1 Apr 2025

Researchers receive $2.7 million NIH grant to develop the next generation of synthetic blood

Blood loss is the leading cause of death in trauma patients between the ages of 1 and 46 years, largely because they cannot access safe blood sources quickly enough. A possible solution? Freeze-dried synthetic blood.

31 Mar 2025

Study helps characterize how sleep deficiency may relate to Alzheimer's pathogenesis

New research reveals that lower proportions of specific sleep stages are associated with reduced brain volume in regions vulnerable to the development of Alzheimer's disease over time.

31 Mar 2025

Blood test offers insight into Alzheimer's stage and severity

A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden.

31 Mar 2025

GLDH proposed as a more accurate biomarker for liver injury detection

Researchers from Critical Path Institute's® (C-Path) Predictive Safety Testing Consortium have proposed glutamate dehydrogenase (GLDH) as a more liver-specific biomarker for detecting liver injury, supporting clearer decision-making.

28 Mar 2025

Scientists develop lab model to study TDP-43 accumulation in neurodegeneration

Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a newly published study, researchers report 'seeding' this accumulation through fragments of the culprit protein created in the lab.

28 Mar 2025

Study points to single respiratory virus as cause of Kawasaki disease

Research from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago strongly suggests that Kawasaki disease is caused by a single respiratory virus that is yet to be identified.

27 Mar 2025

Terahertz imaging reveals cochlear structures with high resolution

Researchers have discovered a groundbreaking use of terahertz (THz) imaging to visualize cochlear structures in mice, offering non-invasive, high-resolution diagnostics. By creating 3D reconstructions, this technology opens new possibilities for diagnosing hearing loss and other conditions.

27 Mar 2025

AI matches pathologists in diagnosing celiac disease

A machine learning algorithm developed by Cambridge scientists was able to correctly identify in 97 cases out of 100 whether or not an individual had coeliac disease based on their biopsy, new research has shown.

27 Mar 2025

$Unraveling CD47's role in bone fracture healing$

Unraveling CD47's role in bone fracture healing

Bone fracture healing is a highly coordinated process involving inflammation, fibrovascular formation, and mineralization.

27 Mar 2025

High blood pressure can lead to structural changes in the kidneys

A research team from the Medical University of Vienna has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes.

27 Mar 2025

Study uncovers protective mechanism of BRCA2 in cancer treatment

Mutations in BRCA2 — a gene known to repair damaged DNA and suppress tumor formation — can predict an individuals' predisposition to develop breast cancer, ovarian, prostate, pancreatic, and other epithelial tumors.

26 Mar 2025

AI is as good as pathologists at diagnosing coeliac disease, study finds

26 Mar 2025

Early antibiotic exposure may boost risk of diabetes later in life

Exposure to antibiotics during a key developmental window in infancy can stunt the growth of insulin-producing cells in the pancreas and may boost risk of diabetes later in life, new research in mice suggests.

25 Mar 2025

C. diff uses toxic compound to gain competitive advantage in the gut

The pathogen C. diff - the most common cause of health care-associated infectious diarrhea - can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut.

25 Mar 2025

Blocking Piezo2 may offer a new therapeutic approach for pulmonary fibrotic diseases

Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting the expression or function of Piezo2, a receptor that senses mechanical forces in tissues including stress, strain, and stiffness.

25 Mar 2025

Natural product derivative demonstrates promising therapeutic potential for psoriasis

Announcing a new publication for Acta Materia Medica journal. Phosphodiesterase-4 (PDE4), a member of the phosphodiesterase superfamily, has highly important roles in cyclic nucleotide signaling pathways and a variety of skin disorders.

25 Mar 2025

Blood test shows high accuracy in detecting Alzheimer's in Asian populations

A study in Alzheimer's & Dementia, a leading journal in dementia research, has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid (Aβ) pathology, a hallmark of Alzheimer's disease (AD).

25 Mar 2025

ADHD may be linked to increased risk of developing dementia later in life

An adult brain affected by attention deficit disorder with or without hyperactivity (ADHD) presents modifications similar to those observed in individuals suffering from dementia.

25 Mar 2025

Study reveals key role of Treg cells in preventing autoimmune responses

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body.

22 Mar 2025