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Researchers call for new genetic tests for congenital diseases

Researchers have discovered that genetic mutations called epivariations are the cause of certain neurodevelopmental disorders and congenital diseases.

25 May 2018

Study establishes the importance of haploid cells

A new study has found that when the cell replication process exceeds or has less than a pair of chromosome set (a genome), destabilization occurs.

25 May 2018

Researchers identify novel epigenetic mutations as cause of neurodevelopmental, congenital disorders

Researchers have identified a type of genetic aberration to be the cause of certain neurodevelopmental disorders and congenital diseases, such as autism and congenital heart disease, which are undetectable by conventional genetic testing.

25 May 2018

SLU researcher aims to find solutions for diabetes patients at risk of hypoglycemia

A $150,000 grant from The Leona M. and Harry B. Helmsley Charitable Trust will support research at Saint Louis University led by scientist Gina Yosten, Ph.D. Yosten's team is pursuing solutions for people with diabetes who are at risk of life-threatening drops in blood sugar known as hypoglycemia.

25 May 2018

New study puts forth most comprehensive tree of life for malaria parasites

A new study led by the American Museum of Natural History puts forth the most comprehensive tree of life for malaria parasites to date.

24 May 2018

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ of the immune system, and without functional immune cells. The boy also presented with cardiac and skeletal defects, dysmorphic craniofacial features and some signs of autistic behaviors.

23 May 2018

Researchers complete genomic map of chronic lymphocytic leukemia

Researchers have created a high-resolution map of the entire epigenome of chronic lymphocytic leukemia, the most common form of leukemia.

23 May 2018

Mapping the Genes Responsible for Pluripotency

Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.

23 May 2018

Malaria-causing parasite seeks refuge inside the liver to replicate and survive

When the malaria-causing Plasmodium parasite first slips into the human bloodstream, injected by the bite of an infected mosquito, it does not immediately target red blood cells.

23 May 2018

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

How can we detect cancer and viruses with high sensitivity? Physical chemist Laura Fabris - an associate professor in the Materials Science and Engineering Department at Rutgers, the State University of New Jersey, and principal investigator of the Fabris NanoBio Group - is addressing this very question.

22 May 2018

Are you and your primary care doc ready to talk about your DNA?

If you have a genetic mutation that increases your risk for a treatable medical condition, would you want to know? For many people the answer is yes. But such information is not commonly part of routine primary care.

22 May 2018

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

ToolGen, Inc., a biotechnology company specializing in genome editing, today announced data demonstrating that blocking a molecular pathway that down-regulates T-cell activity with the Company’s CRISPR/Cas9 gene editing platform results in increased T-cell receptor signaling, in vitro, and in improved anti-tumor activity when tested against in a mouse glioblastoma tumor model.

22 May 2018

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Geneticists have been using model organisms ranging from the house mouse to the single-cell bakers' yeast, Saccharomyces cerevisiae, to study basic biological processes that regulate human development and physiology, and that can be compromised in various diseases.

22 May 2018

Scientists identify new drug target to combat chikungunya virus

Scientists have identified a molecule found on human cells and some animal cells that could be a useful target for drugs against chikungunya virus infection and related diseases, according to new research published in the journal Nature.

21 May 2018

Scientists collate evidence for mismatch between past evolutionary adaptation and modern lives

The transition to modernity - largely driven by the Industrial Revolution - provided us with easier access to food and clean water, with antibiotics, vaccines, and modern medicine.

21 May 2018

Study brings fresh insights into biology of malaria parasite

A team of researchers led by a University of California, Riverside, scientist has found that various stages of the development of human malaria parasites, including stages involved in malaria transmission, are linked to epigenetic features and how chromatin -- the complex of DNA and proteins within the nucleus -- is organized and structured in these parasites.

18 May 2018

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells.

18 May 2018

Scientists identify new potential target to combat acute myeloid leukemia

AML is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated.

18 May 2018

Whole genome sequencing could prevent transfusion reactions

Researchers have recently published a study which may reduce complications and save lives for blood transfusion recipients.

18 May 2018

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth.

17 May 2018

Genome News and Research

Researchers call for new genetic tests for congenital diseases

Study establishes the importance of haploid cells

Researchers identify novel epigenetic mutations as cause of neurodevelopmental, congenital disorders

SLU researcher aims to find solutions for diabetes patients at risk of hypoglycemia

New study puts forth most comprehensive tree of life for malaria parasites

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

Researchers complete genomic map of chronic lymphocytic leukemia

Mapping the Genes Responsible for Pluripotency

Malaria-causing parasite seeks refuge inside the liver to replicate and survive

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

Are you and your primary care doc ready to talk about your DNA?

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Scientists identify new drug target to combat chikungunya virus

Scientists collate evidence for mismatch between past evolutionary adaptation and modern lives

Study brings fresh insights into biology of malaria parasite

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

Scientists identify new potential target to combat acute myeloid leukemia

Whole genome sequencing could prevent transfusion reactions

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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