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UT Southwestern Medical Center geneticist named 2015 recipient of Pearl Meister Greengard Prize

UT Southwestern Medical Center geneticist Dr. Helen Hobbs is the 2015 recipient of the prestigious Pearl Meister Greengard Prize. The prize recognizes Dr. Hobbs' research, which advances understanding of heart disease and other complex disorders.

29 Sep 2015

Kolltan announces presentation of data from KTN0158 preclinical study in mast cell tumors at ESMO 2015

Kolltan Pharmaceuticals, Inc. today announced the presentation of data from a preclinical study evaluating KTN0158 in dogs with spontaneous mast cell tumors. KTN0158 is a proprietary, humanized anti-KIT IgG1 monoclonal antibody drug candidate being developed as a potential therapy for cancer and mast cell-related diseases.

28 Sep 2015

Researchers develop methodology to monitor changes in DNA methylation patterns in individual cells

Whitehead Institute researchers have developed a methodology to monitor changes in DNA methylation over time in individual cells.

26 Sep 2015

TUM scientists develop molecules that could pave way for new treatments to fight Alzheimer's, diabetes

When proteins change their structure and clump together, formation of amyloid fibrils and plaques may occur. Such 'misfolding' and 'protein aggregation' processes damage cells and cause diseases such as Alzheimer's and type 2 diabetes. A team of scientists from the Technical University of Munich headed by Professor Aphrodite Kapurniotu have now developed molecules that suppress protein aggregation and could pave the way for new treatments to combat Alzheimer's, type 2 diabetes and other cell-degenerative diseases.

26 Sep 2015

Scientists identify different CRISPR system with potential to advance genetic engineering

A team including the scientist who first harnessed the revolutionary CRISPR-Cas9 system for mammalian genome editing has now identified a different CRISPR system with the potential for even simpler and more precise genome engineering.

26 Sep 2015

Amgen gets positive CHMP opinions for Kyprolis (carfilzomib) and BLINCYTO (blinatumomab)

"We are pleased to receive positive CHMP opinions for Kyprolis and BLINCYTO as this is an important step in providing new treatment options for patients in Europe with rare forms of cancer," said Sean E. Harper, M.D., executive vice president of Research and Development at Amgen.

25 Sep 2015

DNA nanostructures provide novel applications in molecular medicine

Researchers from Aalto University have published an article in the recent Trends in Biotechnology journal. The article discusses how DNA molecules can be assembled into tailored and complex nanostructures, and further, how these structures can find uses in therapeutics and bionanotechnological applications.

25 Sep 2015

Rhythm Metabolic awarded FDA grant to advance ongoing setmelanotide clinical trial in Prader-Willi syndrome

Rhythm announced today the award of a $1 million research grant from the FDA Office of Orphan Products Development to its subsidiary, Rhythm Metabolic, Inc., to support the ongoing Phase 2 clinical trial of setmelanotide, the company's novel peptide MC4 agonist, for the treatment of obesity and hyperphagia in Prader-Willi syndrome (PWS).

24 Sep 2015

Matricellular proteins may be key therapeutic targets for common ocular disorders

A special issue of Journal of Ocular Pharmacology and Therapeutics highlights the latest research on matricellular proteins, which play a critical role in inflammation and blood vessel formation in the eye and therefore making them key targets for new therapies to treat common ocular disorders such as glaucoma, dry eye disease, and age-related macular degeneration (AMD).

23 Sep 2015

UNC Lineberger earns 'exceptional' rating from NCI for major grant application

The UNC Lineberger Comprehensive Cancer Center earned an "exceptional" rating from the National Cancer Institute for a major grant application associated with the center's multidisciplinary research.

23 Sep 2015

Findings may suggest new therapeutic target to combat memory loss in aging, Alzheimer's disease

Northwestern Medicine scientists have examined activity in a little-studied part of the brain associated with memory and found for the first time the reason that neurons there become more active in old age, findings that may suggest a new target for future therapies to combat memory loss in aging and Alzheimer's disease.

23 Sep 2015

FDA approves Impax Laboratories' generic version of Testred Capsules 10 mg

Impax Laboratories, Inc. today announced that the U.S. Food and Drug Administration has approved its generic version of Testred Capsules 10 mg.

22 Sep 2015

Scientists uncover how embryonic stem cells inhibit virus expression

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, Singapore, have uncovered the mechanisms which embryonic stem cells employ to inhibit virus expression.

22 Sep 2015

Palatin Technologies reports net loss of $12.1 million for fourth quarter 2015

Palatin Technologies, Inc., a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical need and commercial potential, today announced results for its fourth quarter and fiscal year ended June 30, 2015.

21 Sep 2015

Glide Technologies, Cilian collaborate to develop solid dose formulation of recombinant influenza vaccine

Glide Technologies, the development company focused on solid dose formulations of therapeutics and vaccines, today announced that it has entered a collaboration with German biotechnology company Cilian AG to develop a solid dose formulation of Cilian's experimental recombinant influenza vaccine, CiFlu, for delivery using Glide's patient-friendly SDI delivery device.

21 Sep 2015

NYSCF, Q-State partner to advance precision medicine for nervous system disorders

The New York Stem Cell Foundation and Q-State Biosciences are partnering in a joint research collaboration to advance patient care for nervous system disorders through precision medicine. Through this collaboration, both organizations will further advance their respective technologies, while exploring how their proprietary research platforms might provide synergies in the process of developing novel therapeutics and companion diagnostics.

21 Sep 2015

New study highlights gap in scientific knowledge about some diabetes drugs

A gap in scientific knowledge about a family of drugs that are used to treat Type 2 diabetes has been highlighted in a new study.

21 Sep 2015

UC San Diego, TSRI form new consortium to map cells in space and time

Drawing on complementary strengths of two San Diego institutions, The Scripps Research Institute (TSRI) and the University of California, San Diego (UC San Diego) have formed a new consortium with a big mission: to map cells in space and time.

18 Sep 2015

Public lecture discusses the future beyond antibiotics

Pioneering research into bacteriophage therapy as an alternative to antibiotics will be discussed at this year’s Frank May Prize Lecture on Monday 21 September from 5.30 – 6.30pm in the Frank and Katherine May Lecture Theatre, Henry Wellcome Building at the University of Leicester.

17 Sep 2015

Benitec Biopharma initiates new site for ongoing Phase 1/2a TT-034 trial for hepatitis C

Benitec Biopharma Limited, a clinical-stage biotechnology company developing innovative therapeutics based on its gene-silencing technology, DNA-directed RNA interference (ddRNAi), is pleased to announce it has initiated a new site for its ongoing Phase 1/2a TT-034 trial at the Methodist Health System Clinical Research Institute in Dallas, Texas.

16 Sep 2015

Therapeutics News and Research

UT Southwestern Medical Center geneticist named 2015 recipient of Pearl Meister Greengard Prize

Kolltan announces presentation of data from KTN0158 preclinical study in mast cell tumors at ESMO 2015

Researchers develop methodology to monitor changes in DNA methylation patterns in individual cells

TUM scientists develop molecules that could pave way for new treatments to fight Alzheimer's, diabetes

Scientists identify different CRISPR system with potential to advance genetic engineering

Amgen gets positive CHMP opinions for Kyprolis (carfilzomib) and BLINCYTO (blinatumomab)

DNA nanostructures provide novel applications in molecular medicine

Rhythm Metabolic awarded FDA grant to advance ongoing setmelanotide clinical trial in Prader-Willi syndrome

Matricellular proteins may be key therapeutic targets for common ocular disorders

UNC Lineberger earns 'exceptional' rating from NCI for major grant application

Findings may suggest new therapeutic target to combat memory loss in aging, Alzheimer's disease

FDA approves Impax Laboratories' generic version of Testred Capsules 10 mg

Scientists uncover how embryonic stem cells inhibit virus expression

Palatin Technologies reports net loss of $12.1 million for fourth quarter 2015

Glide Technologies, Cilian collaborate to develop solid dose formulation of recombinant influenza vaccine

NYSCF, Q-State partner to advance precision medicine for nervous system disorders

New study highlights gap in scientific knowledge about some diabetes drugs

UC San Diego, TSRI form new consortium to map cells in space and time

Public lecture discusses the future beyond antibiotics

Benitec Biopharma initiates new site for ongoing Phase 1/2a TT-034 trial for hepatitis C

Industry Focus eBook - Microbiome (1st edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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