immunity News and Research

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Resverlogix presents new data on RVX-208 orally active BET inhibitor at ESC Congress 2015

Resverlogix Corp. is pleased to announce that Dr. Norman Wong, chief scientific officer of Resverlogix Corp. presented new data at the European Society of Cardiology (ESC) Congress 2015 in a poster presentation titled: "RVX-208, an orally active BET inhibitor, lowers CVD risk by activities beyond raising ApoA-I/HDL."

31 Aug 2015

Adaptive immune system plays active role in guiding development of mammary glands

In experiments with mouse tissue, UC San Francisco researchers have discovered that the adaptive immune system, generally associated with fighting bacterial and viral infections, plays an active role in guiding the normal development of mammary glands, the only organs--in female humans as well as mice--that develop predominately after birth, beginning at puberty.

28 Aug 2015

Vaccine exemption levels low, vaccination rates high in U.S.

Vaccine exemption levels for kindergarteners are low for most states and infant vaccination rates are high nationally, according to data from two reports published in this week's Morbidity and Mortality Weekly Report.

28 Aug 2015

Study sheds further light on the way APOL1 protein kills trypanosmoe

The African trypanosome Trypanosoma brucei is a blood parasite capable of infecting many mammals. Humans are provided with natural immunity against infection through the activity of the protein apolipoprotein L1 (APOL1): captured via endocytosis, APOL1 forms pores in the lysosomal membrane, leading to the death of the trypanosome.

27 Aug 2015

Single dose of oral cholera vaccine could save more lives in crisis situations

An oral cholera vaccine that is in short supply could treat more people and save more lives in crisis situations, if one dose were dispensed instead of the recommended two, new Johns Hopkins Bloomberg School of Public Health research suggests.

27 Aug 2015

Researchers discover new hepatitis A-like virus in seals

Scientists in the Center for Infection and Immunity at Columbia University's Mailman School of Public Health have discovered a new virus in seals that is the closest known relative of the human hepatitis A virus. The finding provides new clues on the emergence of hepatitis A.

26 Aug 2015

Novel synthetic DNA vaccine induces protective immunity against MERS virus in animal study

A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East Respiratory Syndrome (MERS) coronavirus in animal species, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

21 Aug 2015

Discovery provides new insights into how asthma may be caused

Researchers from the University of Leicester and University Hospitals of Leicester NHS Trust, working with the National Institute of Allergy and Infectious Diseases and Genentech, have discovered new insights into how asthma may be caused, by identifying three distinct groups of asthma patients characterised by the activity of different genes in an individual's airways.

20 Aug 2015

Experimental MERS-CoV vaccine shows promise in monkeys and camels

National Institutes of Health scientists and colleagues report that an experimental vaccine given six weeks before exposure to Middle East respiratory syndrome coronavirus (MERS-CoV) fully protects rhesus macaques from disease. The vaccine also generated potentially protective MERS-CoV antibodies in blood drawn from vaccinated camels.

20 Aug 2015

Researchers capture images of immune cell interactions rallying to destroy herpes simplex virus

Doctor Scott Mueller and colleagues from the University of Melbourne's Department of Microbiology and Immunology at the Doherty Institute used state-of-the-art microscopy to painstakingly capture images of the interactions of three crucial types of immune cells rallying to destroy herpes simplex virus.

19 Aug 2015

Early exposure to inflammatory cytokines can paralyze CD4 T cells

In a discovery that is likely to rewrite immunology text books, researchers at UC Davis have found that early exposure to inflammatory cytokines, such as interleukin 2, can "paralyze" CD4 T cells, immune components that help orchestrate the body's response to pathogens and other invaders.

19 Aug 2015

Bacteria in gut may be the cause of uveitis in the eye

The inflammatory eye disorder autoimmune uveitis occurs when a person's immune system goes awry, attacking proteins in the eye. What spurs this response is a mystery, but now a study on mice suggests that bacteria in the gut may provide a kind of training ground for immune cells to attack the eye.

19 Aug 2015

PHIV children may lack immunity against measles, mumps, and rubella despite vaccination

Between one-third and one-half of individuals in the United States who were infected with HIV around the time of birth may not have sufficient immunity to ward off measles, mumps, and rubella--even though they may have been vaccinated against these diseases.

14 Aug 2015

New combination vaccine may reduce number of injections for young children

A new combination vaccine may reduce the number of injections required to keep infants and toddlers up to date with the United States infant immunization schedule recommended by the Centers for Disease Control and Prevention. In a phase III trial reported in the August 2015 issue of Pediatrics, the vaccine was determined to be effective, safe and well-tolerated. Gary S. Marshall, M.D., professor of pediatrics at the University of Louisville, was the principal investigator of the multi-center trial and first author of the report.

13 Aug 2015

Increasing vaccination coverage in the US protects against chickenpox

Since the chickenpox vaccine became available in the U.S. in 1995, there has been a large reduction in chickenpox cases. Hospitalizations and outpatient visits for chickenpox have continued their decline after a second dose of the vaccine was recommended to improve protection against the disease, according to a new study published in the Journal of the Pediatric Infectious Diseases Society.

13 Aug 2015

Researchers discover way to prevent flu infection without any help from the virus

Researchers have discovered a way to trigger a preventive response to a flu infection without any help from the usual players - the virus itself or interferon, a powerful infection fighter.

12 Aug 2015

AOA urges all people to focus on vaccination

Back to school is an annual reminder to make sure children are fully vaccinated. But vaccination is a life-long health concern and the American Osteopathic Association urges adults to use the seasonal cue to ensure their own immunizations are up to date.

12 Aug 2015

New study reveals role of hydrogen sulfide gas in autoimmune disease

The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells, or Tregs. Tregs ensure that inflammatory responses don't get out of hand and do damage. In autoimmune diseases, sometimes these Treg cells don't act as they should.

12 Aug 2015

Study: Chickenpox vaccination increases incidence of shingles in younger adults

Vaccinating one-year-olds against chickenpox could temporarily nearly double the incidence of shingles in the wider population, but in younger adults than previously thought.

12 Aug 2015

Study may lead to effective antimicrobial treatment strategies for people with uncontrolled diabetes

Case Western Reserve scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with the body's natural infection-control defenses.

7 Aug 2015

immunity News and Research

Resverlogix presents new data on RVX-208 orally active BET inhibitor at ESC Congress 2015

Adaptive immune system plays active role in guiding development of mammary glands

Vaccine exemption levels low, vaccination rates high in U.S.

Study sheds further light on the way APOL1 protein kills trypanosmoe

Single dose of oral cholera vaccine could save more lives in crisis situations

Researchers discover new hepatitis A-like virus in seals

Novel synthetic DNA vaccine induces protective immunity against MERS virus in animal study

Discovery provides new insights into how asthma may be caused

Experimental MERS-CoV vaccine shows promise in monkeys and camels

Researchers capture images of immune cell interactions rallying to destroy herpes simplex virus

Early exposure to inflammatory cytokines can paralyze CD4 T cells

Bacteria in gut may be the cause of uveitis in the eye

PHIV children may lack immunity against measles, mumps, and rubella despite vaccination

New combination vaccine may reduce number of injections for young children

Increasing vaccination coverage in the US protects against chickenpox

Researchers discover way to prevent flu infection without any help from the virus

AOA urges all people to focus on vaccination

New study reveals role of hydrogen sulfide gas in autoimmune disease

Study: Chickenpox vaccination increases incidence of shingles in younger adults

Study may lead to effective antimicrobial treatment strategies for people with uncontrolled diabetes

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