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Study shows the importance of social support in buffering genetic depression risk

Reaching out to support a person when they're under stress is always a good idea. But a new study suggests that support could be especially important for someone whose genetic makeup makes them more likely to develop depression.

13 Jan 2023

American Academy of Pediatrics releases the first clinical practice guideline for evaluating and treating childhood obesity

A recent news article published by the American Academy of Pediatrics (AAP) discussed the first clinical practice guideline released by the AAP to effectively and safely evaluate and treat pediatric obesity in children and adolescents.

13 Jan 2023

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Researchers reviewed the impact of the interactions between the respiratory microbiota and the immune system.

13 Jan 2023

Review and meta-analysis suggests breathwork may be effective for improving stress and mental health

The findings of a study published in Scientific Reports suggest that practicing breathing exercises helps decrease stress and improve mental health.

13 Jan 2023

Researchers study bacterial co-infections and antibiotic use in COVID-19 patients

Researchers estimated the frequency of bacterial co-infections among hospitalized coronavirus disease 2019 (COVID-19) patients and of antibiotic prescriptions in the initial COVID-19 period for appraising the usage of antibiotic stewardship criteria.

13 Jan 2023

What is pharmaceutical forecasting?

In this interview News Medical is talking to David James about pharmaceutical forecasting, J+D Forecasting solutions and their plans for the future.

From J+D Forecasting 13 Jan 2023

New cooling strategy could prevent the growth of glioblastoma

Cooling brain tumor cells to stop them from dividing without killing healthy cells extended the survival of glioblastoma (GBM) animal models dramatically in a study led by a UT Southwestern resident.

12 Jan 2023

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

A new CRISPR-Cas9 approach that targets a detrimental signaling pathway in the heart confers protection from ischemia/reperfusion injury, according to a study in mice.

12 Jan 2023

New technique could overcome the delivery hurdles faced by promising mRNA therapies

A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs).

12 Jan 2023

New insights into deadly fungal invasion in people with compromised immune systems

Fungi such as Aspergillus are so common in our surroundings that we breathe in hundreds to thousands of spores every day.

12 Jan 2023

Machine learning-based behavioral intervention can improve end-of-life cancer care

Electronic nudges delivered to health care clinicians based on a machine learning algorithm that predicts mortality risk quadrupled rates of conversations with patients about their end-of-life care preferences, according to the long-term results of a randomized clinical trial published by Penn Medicine investigators in JAMA Oncology today.

12 Jan 2023

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

The Alzheimer's Drug Discovery Foundation and Harrington Discovery Institute at University Hospitals in Cleveland have granted an ADDF-Harrington Scholar Award to Christiane Wrann, PhD, DVM, Associate Professor in Medicine at the Cardiovascular Research Center and the McCance Center for Brain Health at Massachusetts General Hospital and the Harvard Medical School in Boston.

12 Jan 2023

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Oregon State University College of Pharmacy scientists have demonstrated in animal models the possibility of using lipid nanoparticles and messenger RNA, the technology underpinning COVID-19 vaccines, to treat blindness associated with a rare genetic condition.

11 Jan 2023

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases.

11 Jan 2023

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

11 Jan 2023

Medicare policy change may lead to increased inequities in access to heart transplants

A change to Medicare policy surrounding heart transplant may lead to increased inequities in access to transplant for patients with heart failure, a Michigan Medicine study finds.

11 Jan 2023

New genetic test could guide the treatment of ovarian cancer

Researchers have developed an optimized genetic test for ovarian cancer, which helps accurately target an effective but expensive medication.

11 Jan 2023

COVID-19 outcomes in Rituximab treated patients

A new report throws light on SARS-CoV-2 breakthrough infections in patients with certain joint diseases or musculoskeletal conditions who are on rituximab and compares the severity of COVID-19 outcomes in these patients whilst identifying potential risk factors for severe outcomes.

11 Jan 2023

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows.

11 Jan 2023

Combination therapy could be a safe choice for oral opioid maintenance treatment during pregnancy

Current guidelines recommend that pregnant women with opioid use disorder be prescribed either methadone or buprenorphine, but these drugs too have significant potential for abuse.

11 Jan 2023

Therapy News and Research

Study shows the importance of social support in buffering genetic depression risk

American Academy of Pediatrics releases the first clinical practice guideline for evaluating and treating childhood obesity

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Review and meta-analysis suggests breathwork may be effective for improving stress and mental health

Researchers study bacterial co-infections and antibiotic use in COVID-19 patients

What is pharmaceutical forecasting?

New cooling strategy could prevent the growth of glioblastoma

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

New technique could overcome the delivery hurdles faced by promising mRNA therapies

New insights into deadly fungal invasion in people with compromised immune systems

Machine learning-based behavioral intervention can improve end-of-life cancer care

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

Medicare policy change may lead to increased inequities in access to heart transplants

New genetic test could guide the treatment of ovarian cancer

COVID-19 outcomes in Rituximab treated patients

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Combination therapy could be a safe choice for oral opioid maintenance treatment during pregnancy

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