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Study discovers genetic variations that increase heart attack risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

10 May 2018

Researchers identify six genes that predispose carriers to develop medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology.

10 May 2018

Scripps Research professor wins 2018 RSC Bioorganic Chemistry Award

Floyd Romesberg, PhD, professor at The Scripps Research Institute, has won the 2018 Royal Society of Chemistry Bioorganic Chemistry Award for his ground-breaking contributions to the expansion of the genetic alphabet.

9 May 2018

Advances in Cell Lineage Analysis

Dr. Jan Phillip Junker discusses the applications of CRISPR-Cas9 in cell lineage analysis and the development of tomo-seq; a method to study the spatial organization of cells within whole organisms.

9 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Mutations in EBOV-Makona do not alter disease-causing ability in animal models, shows study

Early during the recent Ebola epidemic in West Africa, scientists speculated that the genetic diversity of the circulating Makona strain of virus (EBOV-Makona) would result in more severe disease and more transmissibility than prior strains.

9 May 2018

New findings point to potential therapeutic avenues for leukemia

Scientists have known for decades that the Hox family of transcription factors are key regulators in the formation of blood cells and the development of leukemia.

9 May 2018

Scientists discover how potential new drug targets spinal muscular atrophy

Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic mutation and stop its progression.

8 May 2018

Researchers harness the precision of CRISPR to knock out single genes in yeast

Researchers have used CRISPR-Cas9 to develop a technology that can precisely target any gene in the yeast species Saccharomyces cerevisiae.

8 May 2018

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times.

8 May 2018

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Genes that control the immune system may play role in hair graying

A study has found a link between genes that warn our bodies of a pathogenic infection and genes that play a role in determining hair color.

4 May 2018

New EU collaborative project aims to improve prevention and treatment of stroke

Charité - Universitätsmedizin Berlin is hosting a new EU collaborative project.

4 May 2018

Researchers characterize new protein that plays key role in genetic stability of cells

Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterized a new protein that is important to the genetic stability of our cells.

3 May 2018

Study reveals essential malaria parasite genes

Researchers have exploited a quirk in the genetic make-up of the deadly malaria parasite, Plasmodium falciparum, to create 38,000 mutant strains and then determine which of the organism's genes are essential to its growth and survival.

3 May 2018

‘Splash Away Cancer!’ swimming fundraiser slated for May 19

The 'Splash Away Cancer!' event will take place Saturday, May 19. The swimming fundraiser supports cancer research and patient care programs at The University of New Mexico Comprehensive Cancer Center. The event is sponsored by the Lobo Aquatic Club, UNM Recreational Services and New Mexico Masters Swimming.

2 May 2018

Research findings challenge feasibility of 'shock and kill' approach to cure HIV

Researchers have provided new insight into the cellular processes behind the 'shock and kill' approach to curing HIV, which they say challenges the effectiveness of the treatment.

2 May 2018

New GP-write project to develop ultra-safe cells resistant to natural viruses

The Center for Excellence in Engineering Biology and the leadership of Genome Project-write today announced its first grand-scale community-wide project, to develop "ultra-safe cells" that resist natural viruses and potentially radiation, freezing, aging and cancer.

2 May 2018

Researchers use human and worm data to explore mutational causes of cancer

Researchers at the European Bioinformatics Institute (EMBL-EBI), the University of Dundee and the Wellcome Sanger Institute have used human and worm data to explore the mutational causes of cancer.

2 May 2018

Genome News and Research

Study discovers genetic variations that increase heart attack risk for statin patients

Researchers identify six genes that predispose carriers to develop medulloblastoma

Scripps Research professor wins 2018 RSC Bioorganic Chemistry Award

Advances in Cell Lineage Analysis

Findings confirm analytical principle that describes mutational processes and cancer development

Mutations in EBOV-Makona do not alter disease-causing ability in animal models, shows study

New findings point to potential therapeutic avenues for leukemia

Scientists discover how potential new drug targets spinal muscular atrophy

Researchers harness the precision of CRISPR to knock out single genes in yeast

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Genes that control the immune system may play role in hair graying

New EU collaborative project aims to improve prevention and treatment of stroke

Researchers characterize new protein that plays key role in genetic stability of cells

Study reveals essential malaria parasite genes

‘Splash Away Cancer!’ swimming fundraiser slated for May 19

Research findings challenge feasibility of 'shock and kill' approach to cure HIV

New GP-write project to develop ultra-safe cells resistant to natural viruses

Researchers use human and worm data to explore mutational causes of cancer

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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