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FDA approves drug to increase blood pressure in adults with septic or distributive shock

The U.S. Food and Drug Administration today approved Giapreza (angiotensin II) injection for intravenous infusion to increase blood pressure in adults with septic or other distributive shock.

21 Dec 2017

Novel drug shows promise in treating metastatic kidney cancer

Metastatic kidney cancer remains largely incurable. Despite a dozen treatments and several immunotherapies, survival rates beyond 5 years remain around 10 percent.

21 Dec 2017

Two surgical procedures found to be equally effective in treating infants with hydrocephalus

Implanting a shunt or endoscopically reducing intracranial pressure and reducing fluid production are equally effective in treating infants with hydrocephalus caused by brain infections, according to an international team of researchers, but endoscopy may have fewer down-the-line complications.

21 Dec 2017

New UGR study provides evidence for tramadol’s adverse effects on cycling performance

Tramadol is an opioid pain medication mainly used to treat moderate to severe pain, such as backache or postoperative pain. Although it has not yet been included in the list of banned substances by the World Anti-Doping Agency, the drug has recently generated significant media interest.

20 Dec 2017

New scalp device delivering electric fields improves survival in patients with glioblastoma

A device attached to a patient's scalp that delivers a continuous dose of low-intensity electric fields improves survival and slows the growth of a deadly brain tumor, according to a new clinical trial led by a Northwestern Medicine scientist and published Dec. 19 in the journal JAMA.

19 Dec 2017

Cervical pessary lowers rate of preterm birth

Pregnant women with a short cervix who used a small silicone ring called a cervical pessary to keep their cervix closed had a lower rate of preterm birth at less than 34 weeks.

19 Dec 2017

Electric fields therapy leads to better overall, progression-free survival in glioblastoma patients

Patients with glioblastoma, an aggressive brain tumor who received a type of electric fields therapy that interferes with cell division had better overall survival and survival without progression of the tumor compared to standard chemotherapy.

19 Dec 2017

Ketamine can stop suicidal thoughts finds new study

A study has shown that Ketamine – an anesthetic drug, is capable of reducing and halting suicidal thoughts in depressed patients. The study comes from Columbia University Medical Center (CUMC) who found that it may take only a few hours after administration of ketamine to reduce the suicidal thoughts in the patients.

18 Dec 2017

Study: Ketamine more effective than common sedative in reducing suicidal thoughts

Ketamine was significantly more effective than a commonly used sedative in reducing suicidal thoughts in depressed patients, according to researchers at Columbia University Medical Center.

14 Dec 2017

Radiation therapy can be used to treat patients with life-threatening heart rhythm

Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy - aimed directly at the heart - can be used to treat patients with a life-threatening heart rhythm.

14 Dec 2017

IPM begins first clinical trial of vaginal rings to prevent HIV in women

The nonprofit International Partnership for Microbicides announced today the start of the first clinical trial of vaginal rings designed to slowly release the antiretroviral drug dapivirine over three months to prevent HIV in women.

13 Dec 2017

Study finds barriers to stem cell transplant use among multiple myeloma patients from minority groups

A study by researchers at Mayo Clinic's campus in Jacksonville, Florida has found that barriers to patients receiving stem cell therapy as part of their treatment for multiple myeloma include income, education, insurance status and access to care at an academic center or facility that treats a high volume of patients.

13 Dec 2017

Mayo Clinic study: Increasing physical activity decreases risk of death from lymphoma

An observational study by researchers at Mayo Clinic has found that increasing physical activity not only decreased the risk of death from all causes but also decreased the risk of death specifically from lymphoma.

13 Dec 2017

Experts call for rigorous clinical trials in use of experimental fetal therapy

Citing uncertainties about the risks and benefits of an experimental therapy for fetuses whose kidneys do not develop, bioethicists at Johns Hopkins and a team of medical experts are calling for rigorous clinical trials in the use of a potential treatment, known as amnioinfusion.

12 Dec 2017

FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials

In the first comprehensive analysis of clinical trial enrollment among older adults with blood cancers, researchers from the U.S. Food and Drug Administration found significant gaps in participation among those aged 75 and older when considered against the incidence of these malignancies in this age group, according to research being presented today during the 59th American Society of Hematology Annual Meeting and Exposition in Atlanta.

12 Dec 2017

Parkinson's progression delayed through high-intensity exercise, study says

A new phase 2, multi-site trial conducted at the Northwestern Medicine and University of Colorado School of Medicine suggests that for people with early-stage Parkinson's disease, high-intensity exercise three times a week is safe and can delay the worsening of motor symptoms.

12 Dec 2017

High-intensity exercise decreases worsening of motor symptoms in Parkinson's patients

High-intensity exercise three times a week is safe for individuals with early-stage Parkinson's disease and decreases worsening of motor symptoms, according to a new phase 2, multi-site trial led by University of Colorado Anschutz Medical Campus and Northwestern Medicine scientists.

12 Dec 2017

Huntington's disease drug clears initial hurdles - raising hopes

Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the cause behind this dreaded disease has been found to be effective, safe and well tolerated in a human clinical trial that was conducted by UCL scientists.

11 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

Butler Hospital launches international Alzheimer's disease prevention study

The Memory and Aging Program at Butler Hospital, a member of Care New England and a major teaching affiliate of The Warren Alpert Medical School of Brown University, enrolled one of the initial participants in an international Alzheimer's disease (AD) prevention study.

11 Dec 2017

Clinical Trial News and Research

FDA approves drug to increase blood pressure in adults with septic or distributive shock

Novel drug shows promise in treating metastatic kidney cancer

Two surgical procedures found to be equally effective in treating infants with hydrocephalus

New UGR study provides evidence for tramadol’s adverse effects on cycling performance

New scalp device delivering electric fields improves survival in patients with glioblastoma

Cervical pessary lowers rate of preterm birth

Electric fields therapy leads to better overall, progression-free survival in glioblastoma patients

Ketamine can stop suicidal thoughts finds new study

Study: Ketamine more effective than common sedative in reducing suicidal thoughts

Radiation therapy can be used to treat patients with life-threatening heart rhythm

IPM begins first clinical trial of vaginal rings to prevent HIV in women

Study finds barriers to stem cell transplant use among multiple myeloma patients from minority groups

Mayo Clinic study: Increasing physical activity decreases risk of death from lymphoma

Experts call for rigorous clinical trials in use of experimental fetal therapy

FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials

Parkinson's progression delayed through high-intensity exercise, study says

High-intensity exercise decreases worsening of motor symptoms in Parkinson's patients

Huntington's disease drug clears initial hurdles - raising hopes

Study: Combination targeted therapy has high response rates in AML patients

Butler Hospital launches international Alzheimer's disease prevention study

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