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Australian researchers develop new risk scoring system to predict childhood leukemia relapse

Australian researchers have developed a new risk scoring system for children with leukemia based on missing DNA fragments or 'microdeletions'.

1 Dec 2017

Researchers identify vulnerability for glioblastoma subtypes

Glioblastoma, the most common and aggressive form of brain cancer, typically fails to respond to treatment or rapidly becomes drug resistant.

1 Dec 2017

New targeted treatment could benefit patients with certain pancreatic tumors

Researchers at the University of Cincinnati College of Medicine have shown that a new targeted treatment could benefit patients with certain pancreatic tumors by preventing spread of the cancer and protecting their heart from damage--a direct result of the tumor.

1 Dec 2017

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Johns Hopkins Kimmel Cancer Center researchers and colleagues have identified a novel drug combination therapy that could prime nonsmall cell lung cancers to respond better to immunotherapy.

30 Nov 2017

New immunotherapy study shows positive results in chronic migraine sufferers

A new study of fremanezumab, an immunotherapy that counteracts one of the molecules released during migraine, was found successful in reducing the number of days that chronic migraine sufferers experienced headaches.

30 Nov 2017

Scientists find potential neurobiological marker to help recognize PTSD patients

Scientists at the Universities of Birmingham and Amsterdam hope to have found a new neurobiological marker to help recognize patients with post-traumatic stress disorder (PTSD).

30 Nov 2017

Tailored Activity Program for older veterans with dementia provides positive results

People with dementia often have behavioral symptoms. These include problems with memory, language, and decision-making abilities. People with dementia can also experience changes in mood, such as increased irritability, depression, and anxiety.

29 Nov 2017

AIDA project optimizes use of old antibiotics for better patient care

A European consortium of researchers studied five off-patent community and hospital antibiotics with modern methods. They integrated the results of three randomised controlled clinical trials with extensive non-clinical studies.

29 Nov 2017

University was tipped off to possible unauthorized trials of herpes vaccine

The university that employed a controversial herpes vaccine researcher has told the federal government it learned last summer of the possibility of his illegal experimentation on human subjects.

29 Nov 2017

Synthetic cannabis-like drug found to be safe and effective in treating sleep apnea

A synthetic cannabis-like drug in a pill was safe and effective in treating obstructive sleep apnea in the first large multi-site study of a drug for apnea funded by the National Institutes of Health. The study was conducted at Northwestern Medicine and the University of Illinois at Chicago.

28 Nov 2017

Capsule research could transform treatment for C. difficile infections

An Alberta-led clinical trial has shown Fecal Microbiota Transplant (FMT) is as effective in treating clostridium difficile (C. difficile) infections whether delivered by colonoscopy or by swallowing capsules.

28 Nov 2017

New findings offer hope for children with aggressive brain tumors

Findings published in Oncotarget offer new hope for children with highly aggressive brain tumors like atypical teratoid/rhabdoid tumor (AT/RT) and medulloblastoma.

28 Nov 2017

New cancer drug begins clinical trial in human patients with rare brain tumor

A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of patients with anaplastic astrocytoma, a rare malignant brain tumor, and glioblastoma multiforme, an aggressive late-stage cancer of the brain.

28 Nov 2017

Direct switch of COPD patients from Seretide to Novartis' Ultibro Breezhaler improves lung function

Novartis today announced positive results from the FLASH study examining the safety and efficacy of directly switching chronic obstructive pulmonary disease (COPD) patients from Seretide (salmeterol/fluticasone) 50/500 mcg to Ultibro Breezhaler (indacaterol/glycopyrronium) 110/50 mcg.

27 Nov 2017

Study highlights need for more clinical trials to improve treatment of children with heart disease

Less than one per cent of UK children born with congenital heart disease are enrolled in clinical trials looking to improve treatments, research funded by the British Heart Foundation and led by the University of Birmingham and Birmingham Children's Hospital has found.

23 Nov 2017

Researchers question exclusion of people with prior cancer history from clinical trials

A quarter of newly diagnosed cancer patients 65 or older are survivors who had a prior cancer – often preventing them from participating in clinical trials, researchers from UT Southwestern's Simmons Cancer Center have found.

22 Nov 2017

Physical fitness in children linked to greater volume of gray matter in brain regions

Researchers from the University of Granada have proven, for the first time in history, that physical fitness in children may affect their brain structure, which in turn may have an influence on their academic performance.

21 Nov 2017

$10 million gift creates new center at Northwestern University to study effects of environment on genes

A new $10 million gift from University trustees and supporters Louis A. Simpson '58 and Kimberly K. Querrey will create a center at Northwestern University Feinberg School of Medicine to study the effects of environment on the activation and expression of genes.

21 Nov 2017

Preclinical study shows clear path toward effective treatment for rare bone disease

Researchers at Sanford Burnham Prebys Medical Discovery Institute have led a preclinical study demonstrating that the drug palovarotene suppresses the formation of bony tumors (osteochondromas) in models of multiple hereditary exostoses (MHE).

20 Nov 2017

Experts endorse recommendations for restrictive blood transfusions

By analyzing data from randomized clinical trials comparing blood transfusion approaches, Johns Hopkins experts, along with colleagues at Cleveland Clinic and NYU Langone Medical Center, endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes.

20 Nov 2017

Clinical Trial News and Research

Australian researchers develop new risk scoring system to predict childhood leukemia relapse

Researchers identify vulnerability for glioblastoma subtypes

New targeted treatment could benefit patients with certain pancreatic tumors

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

New immunotherapy study shows positive results in chronic migraine sufferers

Scientists find potential neurobiological marker to help recognize PTSD patients

Tailored Activity Program for older veterans with dementia provides positive results

AIDA project optimizes use of old antibiotics for better patient care

University was tipped off to possible unauthorized trials of herpes vaccine

Synthetic cannabis-like drug found to be safe and effective in treating sleep apnea

Capsule research could transform treatment for C. difficile infections

New findings offer hope for children with aggressive brain tumors

New cancer drug begins clinical trial in human patients with rare brain tumor

Direct switch of COPD patients from Seretide to Novartis' Ultibro Breezhaler improves lung function

Study highlights need for more clinical trials to improve treatment of children with heart disease

Researchers question exclusion of people with prior cancer history from clinical trials

Physical fitness in children linked to greater volume of gray matter in brain regions

$10 million gift creates new center at Northwestern University to study effects of environment on genes

Preclinical study shows clear path toward effective treatment for rare bone disease

Experts endorse recommendations for restrictive blood transfusions

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