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UTHealth researchers find cause for rare type of bleeding disorder

Fifteen years ago, a hematologist came to Dianna Milewicz, M.D., Ph.D., with a puzzle: Multiple generations of an East Texas family suffered from a moderately severe bleeding disorder, but it wasn't hemophilia.

28 Aug 2013

'Helper cells' improve survival rate of transplanted stem cells, finds study

Like volunteers handing out cups of energy drinks to marathon runners, specially engineered "helper cells" transplanted along with stem cells can dole out growth factors to increase the stem cells' endurance, at least briefly, Johns Hopkins researchers report.

28 Aug 2013

New compound offers way to treat migraine and other disorders of central nervous system

For many migraine sufferers, bright lights are a surefire way to exacerbate their headaches. And for some night-shift workers, just a stroll through a brightly lit parking lot during the morning commute home can be enough to throw off their body's daily rhythms and make daytime sleep nearly impossible. But a new molecule that selectively blocks specialized light-sensitive receptors in the eyes could help both these groups of people, without affecting normal vision.

28 Aug 2013

Researchers find specific protein in nearly all high-grade meningiomas

Johns Hopkins researchers say they have found a specific protein in nearly 100 percent of high-grade meningiomas -- the most common form of brain tumor -- suggesting a new target for therapies for a cancer that does not respond to current chemotherapy.

28 Aug 2013

Novel Parkinson’S Target Uncovered

Researchers from Johns Hopkins and the National Cancer Institute (NCI) highlighted a novel mechanism underlying Parkinson's disease while simultaneously putting to rest a previously held theory regarding progression of the disorder. They also identified a compound that alleviates the disease's symptoms in mice.

27 Aug 2013

Sigma Life Science releases genome editing tool for screening and exploratory studies

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, released Sigma CRISPRs, an inexpensive mammalian genome editing tool suitable for screening and exploratory studies.

27 Aug 2013

2ml deep well plate launched by Porvair Sciences

Porvair Sciences has developed the first 96-well round deep well plate that genuinely delivers 2.00 ml liquid capacity / well in an automation compatible SLAS / ANSI footprint. The revolutionary "common wall" design provides a full 2ml round well, round bottom well within a 45mm height limit, thus ensuring full compatibility with most plate handling equipment.

From Porvair Sciences Limited 27 Aug 2013

Research finding could lead to potential treatment for lymphedema

The molecule interleukin-7 is an important immune messenger protein which ensures that a sufficient number of T cells are present in our body for immune defence. Researchers from ETH Zurich have now demonstrated that IL-7 has another important function: it enhances the drainage function of lymphatic vessels, which collect fluid that has leaked out of blood vessels into the body tissue and return it to the bloodstream.

27 Aug 2013

Study reveals role of cadherin receptor BT-R3 in killing action of Cry4B mosquito toxin

Researchers at The University of Texas at Dallas (UTD), led by Dr. Lee Bulla, have demonstrated for the first time the selective cytotoxicity of Bacillus thuringiensis subsp. israelensis Cry4B toxin is mediated by BT-R3.

27 Aug 2013

ASO may correct striatal transcriptional abnormalities and improve behavioral problems in HD mice

Findings from postmortem studies of the brains of Huntington's Disease (HD) patients suggest that transcriptional dysregulation may be an early step in the pathogenesis of HD before symptoms appear. Other studies report transcriptional alterations in the brains of some mouse models of HD.

27 Aug 2013

Scientists finds link between protein phosphorylation and Parkinson's disease

Clues left at the scene of the crime don't always point to the guilty party, as EPFL researchers investigating Parkinson's disease have discovered. It is generally accepted that the disease is aggravated when a specific protein is transformed by an enzyme.

27 Aug 2013

Research Institute at Nationwide Children's Hospital to receive transition-to-scale grants

he Saving Lives at Birth: A Grand Challenge for Development recently shortlisted 53 finalists from around the world from more than 400 entries. Only 22 teams were awarded grants for their bold, new ideas to save the lives of mothers and newborns in developing countries.

27 Aug 2013

Comprehensive test of biomarkers have prognostic and diagnostic value in Parkinson's disease

Perelman School of Medicine researchers at the University of Pennsylvania report the first biomarker results reported from the Parkinson's Progression Markers Initiative (PPMI), showing that a comprehensive test of protein biomarkers in spinal fluid have prognostic and diagnostic value in early stages of Parkinson's disease.

27 Aug 2013

HIV-infected people who carry gene face greater risk of contracting cryptococcal disease

HIV-infected people who carry a gene for a specific protein face a 20-fold greater risk of contracting cryptococcal disease, according to a study published in mBio-, the online open-access journal of the American Society for Microbiology.

27 Aug 2013

Scientists prove 50-year-old hypothesis of RNA 'higher-order' structure

When Francis Crick and James Watson discovered the double helical structure of deoxyribonucleic acid (DNA) in 1953, it began a genetic revolution to map, study, and sequence the building blocks of living organisms.

27 Aug 2013

Engineers create biodegradable needles that penetrate skin and precisely deliver tuberculosis test

Each year, millions of people in the United States get a tuberculosis skin test to see if they have the infection that still affects one third of the world's population. But the standard diagnostic test is difficult to give, because a hypodermic needle must be inserted at a precise angle and depth in the arm to successfully check for tuberculosis.

27 Aug 2013

G Protein News and Research

UTHealth researchers find cause for rare type of bleeding disorder

'Helper cells' improve survival rate of transplanted stem cells, finds study

New compound offers way to treat migraine and other disorders of central nervous system

Researchers find specific protein in nearly all high-grade meningiomas

Novel Parkinson’S Target Uncovered

Sigma Life Science releases genome editing tool for screening and exploratory studies

2ml deep well plate launched by Porvair Sciences

Research finding could lead to potential treatment for lymphedema

Study reveals role of cadherin receptor BT-R3 in killing action of Cry4B mosquito toxin

ASO may correct striatal transcriptional abnormalities and improve behavioral problems in HD mice

Scientists finds link between protein phosphorylation and Parkinson's disease

Research Institute at Nationwide Children's Hospital to receive transition-to-scale grants

Comprehensive test of biomarkers have prognostic and diagnostic value in Parkinson's disease

HIV-infected people who carry gene face greater risk of contracting cryptococcal disease

Scientists prove 50-year-old hypothesis of RNA 'higher-order' structure

Engineers create biodegradable needles that penetrate skin and precisely deliver tuberculosis test

Unique computer technology opens up discovery of smarter drugs to treat illnesses

TSRI scientists find way to use new DNA-editing technology for DNA sequencing

UAB study points to protein pathway that could lead to new treatments for diabetes

Researchers make significant step in understanding and imaging protein synthesis

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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