Clinical Trial News and Research

RSS

UZH leads Europe's largest research on aging

What began in 2012 is now entering its final stages: Europe's largest study on aging. The international research network behind the DO-HEALTH study is led by Heike Bischoff-Ferrari, Professor of Geriatric Medicine and Aging Research at the University of Zurich, and Head of the Department of Geriatrics at the UniversityHospital Zurich and the Waid City Hospital in Zurich, Switzerland.

20 Nov 2017

Drug used to prevent and treat malaria may also be effective for Zika virus

A new collaborative study led by researchers at Sanford Burnham Prebys Medical Discovery Institute and UC San Diego School of Medicine has found that a medication used to prevent and treat malaria may also be effective for Zika virus.

17 Nov 2017

Researchers develop computer program to find new indications for old drugs

Researchers at the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine have developed a computer program to find new indications for old drugs.

16 Nov 2017

Skin patch offers hope for people with peanut allergy

People who suffer from life-threatening peanut allergies may soon be able to cure their condition by wearing a skin patch, according to the findings of a phase 2 trial.

16 Nov 2017

FDA approves drug to treat pediatric, adult patients with rare Sly syndrome

The U.S. Food and Drug Administration today approved Mepsevii (vestronidase alfa-vjbk) to treat pediatric and adult patients with an inherited metabolic condition called mucopolysaccharidosis type VII (MPS VII), also known as Sly syndrome. MPS VII is an extremely rare, progressive condition that affects most tissues and organs.

15 Nov 2017

Stem cell therapy fails to improve walking ability in people with PAD

A stem cell therapy did not improve walking ability in people with peripheral artery disease, although exercise did lead to significant improvements, according to the results of a new Northwestern Medicine clinical trial.

15 Nov 2017

Clinical trial results could lead to treatment of heart disease in Duchenne muscular dystrophy patients

After boys and young men with Duchenne muscular dystrophy received cardiac progenitor cell infusions, medical tests indicated that the patients' hearts appeared improved, results from a new study show. Patients in the study also scored higher on arm strength tests after receiving the cell infusions.

15 Nov 2017

Live births more likely to occur in women with sufficient vitamin D, research finds

Researchers are calling for a randomized clinical trial to investigate the potential role of vitamin D supplementation in improving live birth rates following assisted reproduction treatment.

15 Nov 2017

Aggressive testing unnecessary for patients who go to ER with chest pain, study suggests

Patients who go to the emergency room (ER) with chest pain often receive unnecessary tests to evaluate whether they are having a heart attack, a practice that provides no clinical benefit and adds hundreds of dollars in health-care costs, according to a new study from researchers at Washington University School of Medicine in St. Louis.

15 Nov 2017

Machine learning could detect therapeutic effects with greater sensitivity than conventional tests

Machine learning could improve our ability to determine whether a new drug works in the brain, potentially enabling researchers to detect drug effects that would be missed entirely by conventional statistical tests, finds a new UCL study published in Brain.

15 Nov 2017

MDA announces 13 new research grants to advance treatment for neuromuscular diseases

The Muscular Dystrophy Association today announced 13 new research and development grants totaling $3.5 million to accelerate the development of treatments for muscular dystrophy, ALS and related life-threatening diseases.

14 Nov 2017

Monoclonal antibody effectively blocks development of graft-versus-host disease, research shows

Newly published research provides preclinical proof-of-concept for the ability of PRO 140, a humanized anti-CCR5 monoclonal antibody under development by CytoDyn Inc., to effectively block the development of graft-versus-host disease (GvHD), a potentially lethal complication of bone marrow stem cell (BMSC) transplantation.

14 Nov 2017

Anti-parasite drug acts like tailored medicine against colon, prostate cancer

Medicine against parasites like Tapeworms and Giardia, contains a substance that kills Prostate- and colon cancer.

14 Nov 2017

PCSK9 inhibitor offers clinical benefit to patients with peripheral artery disease

Patients with peripheral artery disease (PAD) are at high risk of heart attack, stroke and cardiovascular death. In addition, PAD patients can suffer major adverse limb events, such as acute limb ischemia - the equivalent of a heart attack in the leg - that can lead to limb loss.

14 Nov 2017

Scientists invent new way of folding and protecting recombinant proteins

A team from the NUS Yong Loo Lin School of Medicine has invented a fundamentally new way of folding and protecting recombinant proteins.

13 Nov 2017

Corneal donor tissue can be safely stored for longer period, study finds

Results from a large, national clinical trial show that corneal donor tissue can be safely stored for 11 days without negatively impacting the success of transplantation surgery to restore vision in people with diseases of the cornea.

10 Nov 2017

Patients with extreme swings in blood pressure more likely to die than those with less variances

Extreme ups and downs in systolic blood pressure may be just as deadly as having consistently high blood pressure, according to a new study from the Intermountain Medical Center Heart Institute in Salt Lake City.

9 Nov 2017

RUDN chemists obtain unusual organic compounds that could be used in pharmaceutics

Researchers from RUDN University conducted an effective three-component reaction, obtaining unusual organic compounds. The latter are structurally similar to a number of biologically active compounds - which makes it possible to use them in pharmaceutics.

9 Nov 2017

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

An analysis of the medical records of patients treated at Massachusetts General Hospital (MGH) for an often-mysterious condition involving damage to small nerve fibers supports the hypothesis that some cases are caused by autoimmune disease and also identifies the first effective treatment option.

9 Nov 2017

New gene therapy trial for X-linked myotubular myopathy offers hope to children

Ann & Robert H. Lurie Children's Hospital of Chicago is one of the few centers participating in ASPIRO, an international Phase 1/2 clinical trial of a gene therapy product called AT132 for X-linked myotubular myopathy – a rare disease characterized by severe muscle weakness, breathing difficulty and early death.

8 Nov 2017

Clinical Trial News and Research

UZH leads Europe's largest research on aging

Drug used to prevent and treat malaria may also be effective for Zika virus

Researchers develop computer program to find new indications for old drugs

Skin patch offers hope for people with peanut allergy

FDA approves drug to treat pediatric, adult patients with rare Sly syndrome

Stem cell therapy fails to improve walking ability in people with PAD

Clinical trial results could lead to treatment of heart disease in Duchenne muscular dystrophy patients

Live births more likely to occur in women with sufficient vitamin D, research finds

Aggressive testing unnecessary for patients who go to ER with chest pain, study suggests

Machine learning could detect therapeutic effects with greater sensitivity than conventional tests

MDA announces 13 new research grants to advance treatment for neuromuscular diseases

Monoclonal antibody effectively blocks development of graft-versus-host disease, research shows

Anti-parasite drug acts like tailored medicine against colon, prostate cancer

PCSK9 inhibitor offers clinical benefit to patients with peripheral artery disease

Scientists invent new way of folding and protecting recombinant proteins

Corneal donor tissue can be safely stored for longer period, study finds

Patients with extreme swings in blood pressure more likely to die than those with less variances

RUDN chemists obtain unusual organic compounds that could be used in pharmaceutics

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

New gene therapy trial for X-linked myotubular myopathy offers hope to children

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer