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Study finds no link between menopausal hormone therapy and increased risk of dementia

Use of menopausal hormone therapy (MHT, also known as hormone replacement therapy, HRT) is not associated with an increased risk of developing dementia, regardless of hormone type, dose, or duration, concludes a large UK study published by The BMJ.

30 Sep 2021

Hippocampus connects separate, distant events to form narrative memories, study shows

People love stories. We find it easier to remember events when they are part of an overarching narrative. But in real life, the chapters of a story don't follow smoothly one from another. Other things happen in between.

30 Sep 2021

New system synthetically reconnects neural circuits using neuropeptides from Hydra

For two people to communicate in a loud, crowded room, they need to be standing side by side. The same is often true for neurons in the brain. But the same way a cell phone allows two people to communicate clearly across the room, new research at the Marine Biological Laboratory (MBL) opened up a new channel of communication in the worm C. elegans brain.

30 Sep 2021

Instrument to measure risk of reverse zoonotic SARS-CoV-2 transmission events from humans to animals

A new study published on the medRxiv* preprint server presents a standardized survey instrument for evaluating risk factors associated with bidirectional zoonotic transmission of SARS-CoV-2 and pathogens. The instrument is particularly focused on settings where humans and animals share close contact.

30 Sep 2021

Wiggling worms offer new clues into the potential impact of diet on Alzheimer's

Worms don't wiggle when they have Alzheimer's disease. Yet something helped worms with the disease hold onto their wiggle in Professor Jessica Tanis's lab at the University of Delaware.

29 Sep 2021

New 'priming' approach may improve the efficacy of chemotherapy for pancreatic cancer

A new approach to 'prime' the tumor environment may improve how effective chemotherapy is for pancreatic ductal adenocarcinoma, one of the most aggressive forms of pancreatic cancer.

29 Sep 2021

Effect of biologic therapy on COVID-19 in children suffering from rheumatic diseases

A new study aimed to determine the course of SARS-CoV-2 infection in children suffering from rheumatic disease and were receiving bDMARD treatment.

29 Sep 2021

Study investigates the mechanism underlying kidney damage in COVID-19 patients

A review article published in the journal Frontiers in Physiology by researchers affiliated with the Federal University of São Paulo in Brazil discusses the mechanisms whereby SARS-CoV-2 damages the kidneys, potentially serving as a basis for further research in pursuit of treatments to prevent severe renal problems and even chronic kidney disease in COVID-19 patients.

29 Sep 2021

Understanding noise-related hearing loss through changes in RNA levels

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions.

29 Sep 2021

New facility established for testing innovative health nanotechnologies

A bespoke nationwide facility for testing innovative nanotechnologies for healthcare applications is to be established at the University of Strathclyde.

29 Sep 2021

Two proteins joined together using a free-standing, rigid link

Researchers at the Paul Scherrer Institute PSI are the first to have joined two proteins together by means of a free-standing, rigid link. The structural element holds the two protein molecules together at a defined distance and angle, much the way a barbell handle connects two weights.

29 Sep 2021

New analysis reveals distinct differences between molecular profiles of 3D and 2D cultured cells

Oncotarget published "Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells" which reported that to ascertain phenotypical differences between these two distinct culture conditions, these authors carried out a comparative proteomic analysis of a membrane fraction obtained from 3D- and 2D-cultured NSCLC model cell line NCI-H23.

29 Sep 2021

Combination of two drugs may help pancreatic and liver cancer patients

A drug candidate discovered and developed decades ago in the laboratory of UC Davis distinguished professor Bruce Hammock may help control the body's raging and often deadly inflammatory response to chemotherapy treatments, especially for pancreatic and liver cancer patients.

29 Sep 2021

Stringent lineage tracing is vital for nerve cell regeneration studies

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration. Their results, which are published in Cell, show that this tracing is far from routine in the field and suggest that earlier studies reporting "striking" regeneration results must be reexamined.

29 Sep 2021

Laboratory News and Research

Study finds no link between menopausal hormone therapy and increased risk of dementia

Hippocampus connects separate, distant events to form narrative memories, study shows

New system synthetically reconnects neural circuits using neuropeptides from Hydra

Instrument to measure risk of reverse zoonotic SARS-CoV-2 transmission events from humans to animals

Wiggling worms offer new clues into the potential impact of diet on Alzheimer's

New 'priming' approach may improve the efficacy of chemotherapy for pancreatic cancer

Effect of biologic therapy on COVID-19 in children suffering from rheumatic diseases

Study investigates the mechanism underlying kidney damage in COVID-19 patients

Understanding noise-related hearing loss through changes in RNA levels

New facility established for testing innovative health nanotechnologies

Two proteins joined together using a free-standing, rigid link

New analysis reveals distinct differences between molecular profiles of 3D and 2D cultured cells

Combination of two drugs may help pancreatic and liver cancer patients

Stringent lineage tracing is vital for nerve cell regeneration studies

Exposure to smoking and mutations in blood cells may lead to a rare cancer that affects immune cells

Clinical study tests novel topical corneal epithelial stem cell-derived product for treating dry eye disease

Study shows Delta variant is main variant causing vaccine breakthrough COVID-19 infections, irrespective of manufacturer

Southeast Asia - A hotspot of many viruses with potential to cause pandemics

Machine learning may predict zoonotic potential of viral genomes

BostonGene and MD Anderson collaborate to advance the development of multiplatform biomarker signatures

Pittcon 2024 - Advancing Science on the West Coast eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo