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New screening technique to test drug compounds used in Ewing sarcoma treatment

In Ewing sarcoma, cancer cells' DNA is unwound abnormally from a condensed, compact state. Once sections of genetic code are open, key genes are turned on to help direct aggressive and cancerous cell growth.

1 Mar 2016

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

The Centre for Addiction and Mental Health and Impel NeuroPharma have signed a licensing agreement to advance a new neuropeptide-based therapeutic approach shown to be effective in treating depression.

1 Mar 2016

Promising therapeutic strategy for relieving neuropathic pain

A specific molecule involved in maintaining pain after a nerve injury has been identified and blocked in mice by Hiroshima University researchers. These results reveal a promising therapeutic strategy for treating neuropathic pain.

1 Mar 2016

Rare disease day focuses on new approach to finding treatment

2,200 babies will be born in the UK on 29th February, of which 30 will die of a rare disease before they are five years old.

29 Feb 2016

Novel mitochondria-specific ceria nanoparticles can effectively suppress neuronal cell death

The brain is an enormous network of communication, containing over 100 billion nerve cells, or neurons, with branches that connect at more than 100 trillion points. They are constantly sending signals through a vast neuron forest that forms memories, thoughts and feelings; these patterns of activity form the essence of each person.

27 Feb 2016

Novel therapeutic approach to target monomeric Tau protein

Dementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

27 Feb 2016

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

UT Southwestern Medical Center researchers have designed and built a microscope capable of creating high-resolution, 3-D images of living cancer cells in realistic, controllable microenvironments.

27 Feb 2016

Researchers unravel biochemical action of antimalarial drug

Malaria is a worldwide menace. According to the Centers for Disease Control and Prevention, over 500,000 individuals died from malaria in 2013 alone. While treatments for the disease exist, cures can also take a hefty physical toll.

26 Feb 2016

Major breakthrough opens door to better understanding of molecular mechanisms of pancreatic cancer

Pancreatic cancer carries a very bleak prognosis for patients. However, a recent breakthrough by two research teams, including one at the Hôpital Maisonneuve-Rosemont (CIUSSS-EST, Montreal) and University of Montreal, has opened the door to a better understanding of the molecular mechanisms that cause this cancer to develop.

26 Feb 2016

Baxalta seeks FDA approval for ADYNOVATE to treat children with hemophilia A and for use in surgical settings

Baxalta Incorporated, a global biopharmaceutical leader dedicated to delivering transformative therapies to patients with orphan diseases and underserved conditions, announced today that it has submitted supplemental Biologics License Applications (sBLAs) to the U.S. Food and Drug Administration seeking approval for the use of ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] to treat children under the age of 12 with hemophilia A and for use in surgical settings.

26 Feb 2016

Researchers launch clinical trials to test novel cellular-immunotherapy to treat three types of blood cancer

Cancer immunology is based upon boosting the body's own immune system to vanquish malignancies. It is among the fastest growing areas of oncology research. Researchers at UC San Diego Moores Cancer Center have launched three clinical trials to test the safety and efficacy of a novel cellular-immunotherapy that uses modified T cells - one of the immune system's primary weapons - to treat three different types of blood cancer that often defy existing therapies.

24 Feb 2016

SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

Researchers at the Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona (IBB-UAB), in collaboration with the biopharmaceutical company SOM Biotech, located in the Barcelona Science Park (PCB), have published, in Nature Communications, the results of a drug repositioning study in which they describe a powerful drug, SOM0226 (tolcapone) that could significantly improve the pharmacological treatment of familial transthyretin amyloidosis (ATTR).

24 Feb 2016

Hiroshima University researchers identify new class of cancer-causing genetic variations

Researchers at Hiroshima University have opened the door to finding a new class of cancer-causing genetic variations.

23 Feb 2016

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Chemotherapy isn't supposed to make your hair fall out -- it's supposed to kill cancer cells. A new molecular delivery system created at U of T Engineering could help ensure that chemotherapy drugs get to their target while minimizing collateral damage.

22 Feb 2016

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer's disease and improvements in monitoring the effects of medication.

22 Feb 2016

New approach could open door to more personalized medications for diabetes patients

New research from the University of Copenhagen points to an entirely new approach for designing insulin-based pharmaceuticals. The approach could open the door for more personalized medications with fewer side effects for Type 1 Diabetes patients.

19 Feb 2016

New drug combination shows promise for patients with non-small cell lung cancer

Lung cancer is the most common cause of cancer-related death in the United States resulting in more than 158,000 deaths each year. With a 5-year survival rate at only 18 percent, the development of new and improved treatment options is needed.

18 Feb 2016

Caltech researchers identify gene that causes severe insomnia when overactivated

Caltech biologists have performed the first large-scale screening in a vertebrate animal for genes that regulate sleep, and have identified a gene that when overactivated causes severe insomnia. Expression of the gene, neuromedin U (Nmu), also seems to serve as nature's stimulant--fish lacking the gene take longer to wake up in the morning and are less active during the day.

18 Feb 2016

Small chemical change to existing antibacterial drug may result in better treatment for TB

Researchers with Vanderbilt University have discovered that one small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis.

17 Feb 2016

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Potsdam-Rehbruecke - Like sucrose (table sugar), the natural disaccharide isomaltulose (PalatinoseTM) consists of glucose and fructose, but it is apparently more suitable for people with type 2 diabetes with regard to regulating blood glucose levels.

17 Feb 2016

Molecule News and Research

New screening technique to test drug compounds used in Ewing sarcoma treatment

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

Promising therapeutic strategy for relieving neuropathic pain

Rare disease day focuses on new approach to finding treatment

Novel mitochondria-specific ceria nanoparticles can effectively suppress neuronal cell death

Novel therapeutic approach to target monomeric Tau protein

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

Researchers unravel biochemical action of antimalarial drug

Major breakthrough opens door to better understanding of molecular mechanisms of pancreatic cancer

Baxalta seeks FDA approval for ADYNOVATE to treat children with hemophilia A and for use in surgical settings

Researchers launch clinical trials to test novel cellular-immunotherapy to treat three types of blood cancer

SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

Hiroshima University researchers identify new class of cancer-causing genetic variations

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

New approach could open door to more personalized medications for diabetes patients

New drug combination shows promise for patients with non-small cell lung cancer

Caltech researchers identify gene that causes severe insomnia when overactivated

Small chemical change to existing antibacterial drug may result in better treatment for TB

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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