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Using 'click chemistry' to create novel multi-protein anti-cancer agents

A potent anti-cancer therapy has been created using Nobel prize-winning "click chemistry", where molecules click together like LEGO bricks, in a new study by UCL and Stanford University researchers.

24 Jul 2023

USC study reveals key details about how cancer cells metastasize

A surprising finding from USC reveals key details about how cancer cells metastasize and suggests new therapeutic approaches for halting their spread.

24 Jul 2023

Discovery redefines current understanding of immune cell landscape in the human cornea

University of Melbourne researchers have discovered that the sentinels guarding the healthy human cornea from pathogens and inflammation are T cells, and not another type of immune cells called dendritic cells, as previously thought.

24 Jul 2023

New understanding of wasting could lead to better treatments for infections

Although infections can present with many different symptoms, one common symptom is the loss of fat and muscle, a process called wasting.

24 Jul 2023

Cancer-causing gene also plays a crucial role in aging, study finds

A gene called Myc (pronounced "mick") that is among the most important drivers of cancer in both mice and humans also plays a newly discovered crucial role in aging, according to a new Cell Reports study by researchers at UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine.

24 Jul 2023

Lactate plays a critical role in helping neural stem cells develop into specialized neurons

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

24 Jul 2023

Arming phages with heterologous effectors paves the way for successful UTI treatment

Study demonstrated how phage can be engineered to produce bacteriocins and cell wall hydrolases as antimicrobial effector genes.

24 Jul 2023

Could alpha lipoic acid treat polycystic ovary syndrome?

Authors analyzed the efficacy of alpha lipoic acid (ALA) in treating polycystic ovary syndrome (PCOS).

24 Jul 2023

Study offers a comprehensive analysis of bacterial and fungal alterations in COVID-19

Researchers use nanopore sequencing to determine the fungal and bacterial microbiota in the lungs of COVID-19 and non-COVID-19 patients.

24 Jul 2023

Research reveals therapeutic potential of novel compound in inhibiting oncogene translation

Cutting-edge research at the Luxembourg Institute of Health reveals the ground-breaking therapeutic potential of the compound FL3 in inhibiting oncogene translation and rewiring cancer cell metabolism, opening up new therapeutic opportunities for leukemia patients.

24 Jul 2023

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University Singapore (NTU Singapore) and Massachusetts Institute of Technology (MIT), have discovered a new stress signaling system that enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics.

24 Jul 2023

Fly-to-bedside resource offers new hope for COVID-19 treatments

Millions of deaths and ongoing illnesses caused by the COVID-19 pandemic have prompted scientists to seek new ways of understanding how viruses so skillfully enter and reprogram human cells.

21 Jul 2023

Researchers uncover novel targets for treatment of schistosomiasis

The worms that cause schistosomiasis (Schistosoma mansoni) are unusual in several ways, especially the fact that male and female adults must stay paired together throughout their lives for reproduction to be successful.

21 Jul 2023

Muscle-building supplement may help protect memory and prevent Alzheimer's disease

The secret to protecting your memory may be a staple of a bodybuilder's diet. RUSH researchers recently discovered that a muscle-building supplement called beta-hydroxy beta-methylbutyrate, also called HMB, may help protect memory, reduce plaques and ultimately help prevent the progression of Alzheimer's disease.

21 Jul 2023

IU team makes significant contributions to constructing a Human Reference Atlas

Katy Börner's team from the Luddy School of Informatics, Computing, and Engineering's Cyberinfrastructure for Network Science Center has made significant contributions to constructing a Human Reference Atlas and has led or co-authored six research articles in a just-released HuBMAP package in Nature.

21 Jul 2023

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.

21 Jul 2023

Extracellular vesicles may drive fibrosis in scleroderma

Extracellular vesicles, responsible for cell-to-cell communication, might be a driver of fibrosis in systemic sclerosis, according to a recent paper in Arthritis and Rheumatology.

21 Jul 2023

Penn state researchers receive $2 million NIH grant to develop new bioprinting technology

Developing technology to quickly and efficiently bioprint human tissues at scale is the goal of a new project led by Penn State researchers.

21 Jul 2023

Scripps Research scientists develop AI tool to track the detailed evolution of viral pandemics

Scripps Research scientists have developed a machine-learning system - a type of artificial intelligence (AI) application - that can track the detailed evolution of epidemic viruses and predict the emergence of viral variants with important new properties.

21 Jul 2023

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS).

21 Jul 2023

B Cell News and Research

Using 'click chemistry' to create novel multi-protein anti-cancer agents

USC study reveals key details about how cancer cells metastasize

Discovery redefines current understanding of immune cell landscape in the human cornea

New understanding of wasting could lead to better treatments for infections

Cancer-causing gene also plays a crucial role in aging, study finds

Lactate plays a critical role in helping neural stem cells develop into specialized neurons

Arming phages with heterologous effectors paves the way for successful UTI treatment

Could alpha lipoic acid treat polycystic ovary syndrome?

Study offers a comprehensive analysis of bacterial and fungal alterations in COVID-19

Research reveals therapeutic potential of novel compound in inhibiting oncogene translation

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

Fly-to-bedside resource offers new hope for COVID-19 treatments

Researchers uncover novel targets for treatment of schistosomiasis

Muscle-building supplement may help protect memory and prevent Alzheimer's disease

IU team makes significant contributions to constructing a Human Reference Atlas

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Extracellular vesicles may drive fibrosis in scleroderma

Penn state researchers receive $2 million NIH grant to develop new bioprinting technology

Scripps Research scientists develop AI tool to track the detailed evolution of viral pandemics

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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