Cell News and Research

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Novel catalog of gene-isoform variation unveiled in the developing human brain

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain.

23 May 2024

Study demonstrates causal link between microbial factors and dysfunction of ISCs in colitis

In a study published in Cell Host & Microbe, a research team led by Prof. PAN Wen from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, in collaboration with research teams led by Prof. ZHU Shu and Prof. SONG Xinyang, demonstrated the causal link between microbial factors and dysfunction of intestinal stem cells (ISCs) in colitis.

23 May 2024

New genetic discoveries offer hope for targeted lupus therapies

Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient's immune system - a therapy that has its own serious risks.

23 May 2024

KFF Health News' 'What the Health?': Anti-abortion hard-liners speak up

With abortion shaping up as a key issue for the November elections, the movement that united to overturn Roe v. Wade is divided over going further, faster — including by punishing those who have abortions and banning contraception or IVF.

23 May 2024

Tailoring polymeric micelles for improved olaparib solubility and drug release

Olaparib is a selective poly (ADP-ribose) polymerase inhibitor. However, its clinical application is hindered by low solubility and undesired pharmacokinetic profiles (e.g., relatively short circulation).

23 May 2024

Breakthrough study reveals molecular drivers of Alzheimer's progression

According to the US Centers for Disease Control and Prevention, at least 5.8 million Americans are currently living with Alzheimer's disease, which is the most common form of dementia.

23 May 2024

New optogenetics approach may offer better muscle control with less fatigue

For people with paralysis or amputation, neuroprosthetic systems that artificially stimulate muscle contraction with electrical current can help them regain limb function.

23 May 2024

Investigating the evolution of cell division mechanisms in Ichthyosporea

Cell division is fundamental to life, enabling growth, reproduction, and survival across all organisms, from single-celled bacteria to complex multicellular animals.

23 May 2024

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Diseases that affect the brain and spinal cord can be particularly devastating, and finding new and more effective ways to treat these conditions is an important goal for researchers and clinicians alike.

23 May 2024

Study explores how different modes of cell division evolved in close relatives of fungi and animals

Cell division is one of the most fundamental processes of life. From bacteria to blue whales, every living being on Earth relies on cell division for growth, reproduction, and species survival.

23 May 2024

Sphere Fluidics appoints Curtis Nicholson as Director of Sales, EMEA, to support accelerated growth in key markets

Sphere Fluidics, a leading provider of innovative microfluidics-based solutions for single-cell analysis and isolation, today announced the appointment of Curtis Nicholson as Director of Sales for Europe, Middle East, and Africa (EMEA). Curtis’ appointment will strengthen the Company’s market position in these regions as it progresses ambitious plans for future growth and commercial success.

From Fluidic Sciences and Sphere Bio 23 May 2024

Does prenatal DHA supplementation increase infant fat mass?

Prenatal DHA supplementation increases infant total and central fat mass at 24 months, independent of gestational weight gain and offspring sex. Further research is needed to determine long-term effects.

22 May 2024

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Ferroptosis, an iron-dependent cell death mechanism, is identified as a key factor in severe COVID-19 lung disease, suggesting potential new therapeutic targets.

22 May 2024

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

Hepatocellular carcinoma (HCC), a prevalent form of cancer, profoundly influences the progression and prognosis of the disease through immune response mechanisms.

22 May 2024

LMU study identifies dual genetic pathways increasing cardiovascular disease risk

LMU researchers have discovered two independent ways by which genetic variants increase the risk of cardiovascular diseases.

22 May 2024

Emotional dysregulation identified as core symptom of ADHD

Cambridge scientists have shown that problems regulating emotions – which can manifest as depression, anxiety and explosive outbursts – may be a core symptom of attention deficit hyperactivity disorder (ADHD).

22 May 2024

100-year-old BCG vaccine protects individuals with type 1 diabetes from infectious diseases

In new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.

22 May 2024

Study reveals biological repercussions of UV-C radiation exposure from germicidal lamps

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 9, entitled, "Germicidal lamps using UV-C radiation may pose health safety issues: a biomolecular analysis of their effects on apoptosis and senescence."

22 May 2024

Study suggests miR-377 as potential therapeutic target for prostate cancer

A new research paper was published in Genes & Cancer on May 16, 2024, entitled, "Inhibitory effect of miR-377 on the proliferative and invasive behaviors of prostate cancer cells through the modulation of MYC mRNA via its interaction with BCL-2/Bax, PTEN, and CDK4."

22 May 2024

Single-cell analysis reveals insights into immune responses during xenotransplantation

Surgical teams at NYU Langone Health performed the world's first genetically modified pig kidney transplants into a human body in September and November 2021, and then transplanted two pig hearts in the summer of 2022.

22 May 2024

Cell News and Research

Novel catalog of gene-isoform variation unveiled in the developing human brain

Study demonstrates causal link between microbial factors and dysfunction of ISCs in colitis

New genetic discoveries offer hope for targeted lupus therapies

KFF Health News' 'What the Health?': Anti-abortion hard-liners speak up

Tailoring polymeric micelles for improved olaparib solubility and drug release

Breakthrough study reveals molecular drivers of Alzheimer's progression

New optogenetics approach may offer better muscle control with less fatigue

Investigating the evolution of cell division mechanisms in Ichthyosporea

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Study explores how different modes of cell division evolved in close relatives of fungi and animals

Sphere Fluidics appoints Curtis Nicholson as Director of Sales, EMEA, to support accelerated growth in key markets

Does prenatal DHA supplementation increase infant fat mass?

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

LMU study identifies dual genetic pathways increasing cardiovascular disease risk

Emotional dysregulation identified as core symptom of ADHD

100-year-old BCG vaccine protects individuals with type 1 diabetes from infectious diseases

Study reveals biological repercussions of UV-C radiation exposure from germicidal lamps

Study suggests miR-377 as potential therapeutic target for prostate cancer

Single-cell analysis reveals insights into immune responses during xenotransplantation

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