Genes News and Research

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Lifelong tracking of fish reveals early behavioral signals of aging

Scientists tracking the entire life of the African turquoise killifish have discovered that behavior alone can predict whether an animal will live a long or short life.

12 Mar 2026

Gut microbes may drive memory decline during aging by disrupting vagal brain signaling

Researchers identified in mice a microbiome–gut–brain pathway in which age-associated changes in gut microbes increase medium-chain fatty acids that impair vagal sensory signaling and hippocampal activity. These interoceptive disruptions weaken memory formation, revealing a microbial mechanism that contributes to cognitive decline during aging.

12 Mar 2026

New imaging method maps gene activity across entire zebrafish embryo

How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development?

12 Mar 2026

New study identifies specific brain cells most vulnerable to ALS and dementia

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) belong to a spectrum of neurodegenerative diseases with overlapping symptoms, characterized by muscle wasting, paralysis, dementia, and other serious impairments.

12 Mar 2026

Does coffee disrupt sleep? Large population study suggests the impact may be minimal

A large cross-sectional analysis of 25,381 Swedish adults aged 50–64 found that habitual coffee consumption showed only very weak associations with sleep quality and daytime sleepiness. Genetic analyses confirmed known coffee-related variants and suggested that long-term caffeine exposure may lead to adaptation in the brain’s adenosine signaling system.

11 Mar 2026

Detailed APOL1 gene analysis in Black patients improves kidney disease diagnosis

A closer examination of the APOL1 gene in Black patients with kidney disease can provide more accurate diagnoses than current protocols, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

11 Mar 2026

Scientists map epigenetic changes across aging brain cells

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

11 Mar 2026

DNA-based barcoding reveals which nanoparticles successfully deliver genetic therapies

Drug delivery researchers have vastly improved the potential of genetic therapies by overcoming the challenge of consistently getting genes and gene-editing tools where they need to be within cells.

11 Mar 2026

New review reveals complex polygenic architecture underlying common epilepsies

An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common epilepsies, assembling evidence from genome-wide association studies, whole-exome sequencing projects, and advanced statistical modeling to illuminate the polygenic architecture that underpins these heterogeneous neurological disorders.

10 Mar 2026

AI and genetics reveal new insights into human language development

Learning French, reading the latest Andy Weir novel, hanging out with friends for St. Patrick's Day - language is central to all these everyday activities.

10 Mar 2026

New review calls for biologically grounded approach to psychiatric diagnosis

A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern medicine: psychiatry remains the only major clinical discipline that diagnoses complex illness primarily through conversation and symptom checklists, while fields such as oncology and cardiology long ago embraced laboratory markers, imaging, and molecular profiling.

10 Mar 2026

p38 MAPK drives epigenetic activation of fibrotic genes in lung fibroblasts

A new research paper was published in Volume 18 of Aging-US on March 3, 2026, titled "P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts."

10 Mar 2026

Transposable elements cause majority of lethal mutations in fruit flies

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University.

10 Mar 2026

Researchers discover protein that promotes natural dental pulp tissue regeneration

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth vitality.

10 Mar 2026

Environmental conditions influence how bacteria respond to antibiotic treatments

Antibiotic susceptibility in resistant bacteria is not static. New research shows that bacteria harboring resistance genes may respond differently to antibiotics if they are tested under conditions other than those used in standard laboratory assays.

10 Mar 2026

FOXJ1 gene may drive resistance to taxane chemotherapy in advanced prostate cancer

A gene called FOXJ1 may drive resistance to taxane chemotherapy during treatment for advanced prostate cancer, according to a new study led by investigators at Weill Cornell Medicine and Beth Israel Deaconess Medical Center.

10 Mar 2026

Adelaide University decodes the secrets of cancer survival

A new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.

10 Mar 2026

Enzyme helps maintain retinal progenitor cells during eye development

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain.

9 Mar 2026

Long-read whole genome sequencing uncovers new genetic variants linked to autism

Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder (ASD) by using long-read whole genome sequencing (LR-WGS), an emerging approach that reads large sections of the genome at once, making it easier for scientists to find new genetic variants and understand how genetic variants affect the function of a gene.

9 Mar 2026

Largest genetic study classifies 14 psychiatric disorders into five major groups

Although mental disorders have multifactorial causes, genetics can explain some of them, yet this field remains largely unexplored in terms of guiding diagnoses and treatments.

9 Mar 2026

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Genes News and Research

Lifelong tracking of fish reveals early behavioral signals of aging

Gut microbes may drive memory decline during aging by disrupting vagal brain signaling

New imaging method maps gene activity across entire zebrafish embryo

New study identifies specific brain cells most vulnerable to ALS and dementia

Does coffee disrupt sleep? Large population study suggests the impact may be minimal

Detailed APOL1 gene analysis in Black patients improves kidney disease diagnosis

Scientists map epigenetic changes across aging brain cells

DNA-based barcoding reveals which nanoparticles successfully deliver genetic therapies

New review reveals complex polygenic architecture underlying common epilepsies

AI and genetics reveal new insights into human language development

New review calls for biologically grounded approach to psychiatric diagnosis

p38 MAPK drives epigenetic activation of fibrotic genes in lung fibroblasts

Transposable elements cause majority of lethal mutations in fruit flies

Researchers discover protein that promotes natural dental pulp tissue regeneration

Environmental conditions influence how bacteria respond to antibiotic treatments

FOXJ1 gene may drive resistance to taxane chemotherapy in advanced prostate cancer

Adelaide University decodes the secrets of cancer survival

Enzyme helps maintain retinal progenitor cells during eye development

Long-read whole genome sequencing uncovers new genetic variants linked to autism

Largest genetic study classifies 14 psychiatric disorders into five major groups

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