Immune Response News and Research

RSS

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

New insights into mechanisms of mucosal mast cells in food allergies

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially life-threatening

29 Jan 2025

From gut health to metabolism: How sleep controls more than you think

Study reveals that sleep traits predict over 15% of body characteristics across 15 physiological systems, with visceral fat, cardiovascular health, and metabolism deeply intertwined with sleep patterns.

29 Jan 2025

Leukocyte count predicts severity of COVID-19 symptoms in older women

Thanks to advances in treatment options, a COVID-19 diagnosis is no longer as scary as it once was, at least for most people.

29 Jan 2025

Groundbreaking research reveals key gut cells involved in food tolerance

With every bite of food we take, our intestinal immune system must make a big decision. Tasked with defending us from foreign pathogens, these exquisitely sensitive cells somehow distinguish friend from foe-destroying invaders while tolerating food and helpful bacteria.

28 Jan 2025

New delivery system could improve the effectiveness of peptide-based cancer vaccines

Researchers at the Terasaki Institute for Biomedical Innovation have developed an innovative delivery system that could significantly improve the effectiveness of peptide-based cancer vaccines, according to a new study published in Advanced Functional Materials.

28 Jan 2025

Immune environment found to influence success of leukemia immunotherapy

A research team from Columbia Engineering and the Irving Institute for Cancer Dynamics made a pivotal discovery in the field of cancer immunotherapy.

24 Jan 2025

Researchers investigate a new combination therapy against cancer

A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer.

23 Jan 2025

Researchers discover how location affects immune cells' role in fighting disease

The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease.

22 Jan 2025

Study reveals how gut bacteria influence immune cell training and inflammation

A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the intestinal barrier and reach the bone marrow, where they induce epigenetic changes-modifications that alter gene activity without affecting DNA sequence-in the stem cells that give rise to immune cells.

22 Jan 2025

Long-covid patients are frustrated that federal research hasn’t found new treatments

Erica Hayes, 40, has not felt healthy since November 2020 when she first fell ill with covid.

22 Jan 2025

Study sheds light on the dynamics of non-persistent HPV infections

Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a study published January 21st in the open-access journal PLOS Biology by Samuel Alizon of the National Centre for Scientific Research (CNRS), France, and colleagues.

21 Jan 2025

Study finds anti-correlation of KLRG1 and PD-1 expression in tumor fighting T cells

A new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled "Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells."

21 Jan 2025

Study reveals how children's immune systems react to cancer

Researchers at Karolinska Institutet and the Astrid Lindgren Children's Hospital in Sweden have determined how children's immune systems react to different kinds of cancer depending on their age.

20 Jan 2025

Study uncovers key role of NSP4 in rotavirus disease severity

Researchers at Baylor College of Medicine and collaborating institutions have improved our understanding of how rotavirus, the most common cause of acute gastroenteritis in children, makes people sick.

17 Jan 2025

New discovery in HIV vaccine response reveals surprising antibody behavior

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.

17 Jan 2025

Mapping neuronal IL-1R1 expression reveals insights into brain function

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states.

17 Jan 2025

Cigarette smoke alters immune cell function in the lungs

Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of effective treatments.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

New approach shows promise in fighting multiple cancers

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven in which the tumor can grow. Treatments that target some of these pro-tumor actions are effective in a number of cancers, but only for some patients; in others, these treatments have little effect.

17 Jan 2025