Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

As off-label use spreads, supplies of niche drugs and patients’ patience grow short

Medical treatment has knocked down tumors in 6-year-old Easton Daniels' brain, but the drug used also wiped out his immune system.

24 Sep 2019

Fullerene compounds effectively combat dangerous viral infections

Scientists from the Skoltech Center for Energy Science and Technology and the Institute of Problems of Chemical Physics of RAS in collaboration with researchers from four other Russian and foreign research centers have discovered a new reaction that helps obtain water-soluble fullerene derivatives which effectively combat flu viruses, human immunodeficiency virus, herpes simplex virus, and cytomegalovirus.

23 Sep 2019

Study uncovers new factor in the development of childhood lymphoma

A study recently published in the renowned journal Blood, led by Kaan Boztug, Scientific Director of the St. Anna Children's Cancer Research Institute, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Adjunct Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Associate Professor at the Medical University of Vienna, together with scientists from Israel, Germany, Turkey, Colombia, Argentina and the USA, investigated four patients from independent families with malignancy, autoimmunity and immunodeficiency.

19 Sep 2019

Cellular metabolic overactivity leads to inflammation, research reveals

Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased.

16 Sep 2019

Needle stick injuries are common and can transmit many blood-borne pathogens

Needle stick injuries (NSIs) can transmit more than 20 blood-borne pathogens, including HIV, hepatitis B virus (HBV), hepatitis C virus (HCV) and, more rarely, malaria, human T cell leukemia virus and Ebola.

25 Aug 2019

Despite failed promises, stem cell advocates again want taxpayers to pony up billions

Californians voted in 2004 to shell out billions of dollars in taxpayer money to fund cutting-edge stem cell treatments.

16 Aug 2019

Chlamydia vaccine shows promise after a successful clinical trial

A vaccine against the sexually transmitted infection (STI) chlamydia is now a substantial step closer to reality after successfully passing its Phase 1 clinical trial.

14 Aug 2019

Deadly protein combination reveals new drug targets for viral infections

New research from Cornell University details how two highly lethal viruses have greater pathogenic potential when their proteins are combined.

14 Aug 2019

Research reveals potential target for therapies to prevent severe allergic reactions

Allergies can be life-threatening when they cause anaphylaxis, an extreme reaction with constriction of the airways and a sudden drop in blood pressure.

2 Aug 2019

Researchers explore how HIV spreads in 3D tissue-like environments

The spread of pathogens like the human immunodeficiency virus (HIV) is often studied in a test tube, i.e. in two-dimensional cell cultures, even though it hardly reflects the much more complex conditions in the human body.

25 Jul 2019

New vaccine shows promise against toughest HIV strains

A new study reports successful immunization against a so-far invincible “death star” strain of an HIV-related laboratory virus (SIVmac239) and another tough strain. The new approach also achieves long-term protection with a single dose, showing that gene therapy could allow broad and durable protection, based on a modified form of the CD4 protein that allows HIV entry into human cells.

24 Jul 2019

HIV DNA persists in spinal fluid despite treatment, linked to cognitive impairment

Many people living with the human immunodeficiency virus (HIV) and using antiretroviral therapy (ART) may still have cells sheltering the virus lurking in the cerebrospinal fluid, a new study has found.

16 Jul 2019

People living with HIV have increased risk for heart diseases and face health challenges

Effective antiretroviral therapy has changed the human immunodeficiency virus (HIV) from a progressive, fatal disease to a chronic, manageable condition that is associated with higher rates of heart attacks, strokes, heart failure, sudden cardiac deaths, and other diseases compared to people without HIV, according to a new scientific statement from the American Heart Association published in the Association journal Circulation.

3 Jun 2019

University of Freiburg to receive 25.8 million euros for collaborative research centers

The Deutsche Forschungsgemeinschaft has approved grant applications for two collaborative research centers at the University of Freiburg: one for continued grant funding, and one for initial grant funding.

24 May 2019

University of Miami establishes AIDS Research Center to curb HIV epidemic

The United Nation's goal of ending AIDS around the world by 2030 is undeniably ambitious, but within tantalizing reach.

23 May 2019

Monkey-infecting virus shows promise as potential component of future HIV vaccine

A protein from Simian Immunodeficiency Virus, which can infect monkeys and apes, has shown promise as a potential component of a vaccine against Human Immunodeficiency Virus, in a new study from scientists at Scripps Research in La Jolla, California.

22 May 2019

CU Anschutz researchers identify new immunodeficiency disease

A new immunodeficiency disease caused by a novel genetic mutation has been identified by researchers at the University of Colorado Anschutz Medical Campus providing unique insights into cell biology.

6 May 2019

Breakthrough antibody treatment suppresses HIV without antivirals

A new research paper describes how an antibody that prevents HIV binding to human immune cells was shown to be able to suppress levels of HIV for up to four months.

18 Apr 2019

New gene therapy cures babies with fatal 'Bubble Boy' disease

A new gene therapy created by US researchers appears to have cured eight infant boys born with a rare genetic disorder referred to as “Bubble Boy” disease.