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Amyloid precursor protein fragment may be a biomarker for autism

Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry and the Silver Child Development Center.

4 Jan 2012

NYUCI experts present latest research findings about hematologic cancers at 53rd ASH meeting

Experts from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, presented their latest research findings about hematologic cancers at the 53rd ASH Annual Meeting and Exposition held December 10-13, 2011 in San Diego, California.

14 Dec 2011

Study explores critical role of 14-3-3σ in halting breast cancer progression

New research out of McGill University's Goodman Cancer Research Centre provides compelling new evidence that a gene known as 14-3-3σ plays a critical role in halting breast cancer initiation and progression.

30 Nov 2011

MC3R gene plays an important role in maintaining steady weight

Against the backdrop of the growing epidemic of obesity in the United States, scientists from the Florida campus of The Scripps Research Institute have made an important new discovery regarding a specific gene that plays an important role in keeping a steady balance between our food intake and energy expenditure. The study may help scientists better understand the keys to fighting obesity and related disorders such as diabetes.

24 Nov 2011

New clues about connections among fat, inflammation and insulin resistance

In a new study, scientists report that they substantially curbed weight gain, improved metabolism, and improved the efficacy of insulin in mice by engineering them to express a specific human enzyme in their fat tissue. Although the obesity prevention came at the significant cost of widespread inflammation, the research offers new clues about the connections among obesity, insulin resistance and type 2 diabetes, and inflammation.

14 Nov 2011

New cellular targets for devastating neurological disorder

In a paper published in the November 9 issue of The Journal of Neuroscience, researchers at the University of California, San Diego School of Medicine and University of Washington describe in deeper detail the pathology of a devastating neurological disorder, but also reveal new cellular targets for possibly slowing its development.

10 Nov 2011

Infinity third quarter total revenue increases marginally to $23.3 million

Infinity Pharmaceuticals, Inc. today highlighted its recent clinical and business progress and announced its third quarter 2011 financial results.

9 Nov 2011

Viagra may improve antitumor immunity in people with melanoma

At first it sounds like good news: The body's own immune system gets active in almost every cancer - however, not necessarily for the benefit of the patient. "We distinguish between two different types of immune response," says Professor Dr. Viktor Umansky, immunologist at DKFZ and University Medical Center Mannheim. "On the one hand, cells of the immune system specifically attack tumor cells.

9 Nov 2011

Hirano bodies may play a protective role in progression of Alzheimer's

Hirano bodies are almost indescribably tiny objects found in nerve cells of people suffering from conditions such as Alzheimer's, mad cow and Lou Gehrig's diseases. Yet for decades, researchers weren't sure if these structures helped cause the conditions or appeared after onset of the disease and had some other role.

8 Nov 2011

Cerebellum contributes to creation of cognitive map in the hippocampus

The cerebellum is far more intensively involved in helping us navigate than previously thought. To move and learn effectively in spatial environments our brain, and particularly our hippocampus, creates a "cognitive" map of the environment. The cerebellum contributes to the creation of this map through altering the chemical communication between its neurones. If this ability is inactivated, the brain is no longer able to to create an effective spatial representation and thus navigation in an environment becomes impaired.

4 Nov 2011

Eliminating senescent cells could prevent or delay onset of age-related disorders

Researchers at Mayo Clinic have shown that eliminating cells that accumulate with age could prevent or delay the onset of age-related disorders and disabilities. The study, performed in mouse models, provides the first evidence that these "deadbeat" cells could contribute to aging and suggests a way to help people stay healthier as they age.

3 Nov 2011

Advanced papillary thyroid cancer patients with BRAFV600E gene mutation at higher risk

Individuals with advanced papillary thyroid cancer (PTC) that are associated with the BRAFV600E gene mutation have a higher risk of recurrent disease and progression to more advanced, poorly differentiated thyroid cancer, according to data presented today at the 81st Annual Meeting of the American Thyroid Association (ATA).

28 Oct 2011

Researchers may have solved 100-year-old puzzle to safely open and close the blood-brain barrier

Cornell University researchers may have solved a 100-year puzzle: How to safely open and close the blood-brain barrier so that therapies to treat Alzheimer's disease, multiple sclerosis and cancers of the central nervous system might effectively be delivered.

14 Sep 2011

UB transgenic mouse model of Timothy Syndrome improves understanding of autism

The first transgenic mouse model of a rare and severe type of autism called Timothy Syndrome is improving the scientific understanding of autism spectrum disorder in general and may help researchers design more targeted interventions and treatments.

12 Sep 2011

ATA announces five recipients of 2011 thyroid cancer research grants

The American Thyroid Association (ATA) announced the five recipients of its 2011 research grants, each of whom will receive up to $25,000 annually for up to two years. Three of the five recipients were awarded special ATA ThyCa grants for research projects that focus on thyroid cancer. These grants are funded by ThyCa: Thyroid Cancer Survivors, Inc.

8 Sep 2011

Donald Danforth Center receives $11.9M funding for Virus Resistant Cassava for Africa project

The Donald Danforth Plant Science Center announced today that it has received additional funding totaling $11.9 million for the Virus Resistant Cassava for Africa (VIRCA) project to advance its work to improve the health and wellbeing of farmers, their families, and other consumers of cassava living in Sub Saharan Africa.

8 Sep 2011

Scientists discover two opposing neuronal regulatory circuits for generation, elimination of fear

Emotional balance is regulated by molecular factors behind stress response. When healthy people are faced with threatening situations, they react with a suitable behavioural response and do not descend into a state of either panic or indifference, as is the case, for example, with patients who suffer from anxiety.

7 Sep 2011

Study: Bone marrow transplantation may prolong period of cancer-free survival

Bone marrow transplantation with genetically modified cells may prolong the period of cancer-free survival, suggests a study led by Dr. Vivek Rangnekar, associate director of translational research for the Markey Cancer Center at the University of Kentucky.

25 Aug 2011

Green tea shows promise against two types of tumors, HHS

A compound found in green tea shows great promise for the development of drugs to treat two types of tumors and a deadly congenital disease. The discovery is the result of research led by Principal Investigator, Dr. Thomas Smith at The Donald Danforth Plant Science Center and his colleagues at The Children's Hospital of Philadelphia.

16 Aug 2011

Caffeine in sunscreens may protect from skin cancer: Study

Studies have revealed that drinking caffeinated beverages reduces one’s chances of developing some types of cancer, including UV-associated skin cancer. Now, researchers propose a possible mechanism for this observation—the inhibition of a DNA repair pathway that sensitizes cells to death after sun exposure.

15 Aug 2011