Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Low-glycemic load diets may make dieting easier

Low-glycemic load diets, those low in sugars with moderate levels of carbohydrates and not as low in fat and protein, may lower metabolism less when compared with low-fat diets, making the dieters feel less tired, cold and hungry, as well as improve cardiovascular risk factors

24 Nov 2004

Having diabetes raises a woman's risk of having a heart attack to nearly 10 times

Having diabetes raises a woman's risk of having a heart attack to nearly 10 times that of other women, according to a study in the December issue of Diabetes Care. The study also describes why women with diabetes are at much higher risk than men with diabetes when it comes to having cardiac events.

23 Nov 2004

Experimental compound prevents cholesterol gallstone disease

A promising experimental compound prevents cholesterol gallstone disease in mice by stimulating the biochemical pathway that controls bile acid secretion by the liver, according to new studies by Howard Hughes Medical Institute researchers.

23 Nov 2004

Information about serious adverse effects of cerivastatin were known within months after drug launched

A review of the published literature and of internal company documents from the manufacturer of cerivastatin, a cholesterol lowering drug removed from the market in 2001, suggests that information about serious adverse effects of this medication was known to the company within months after this drug was launched

23 Nov 2004

Patients taking the lipid-lowering medications have a relatively low risk of developing rhabdomyolysis

Patients taking the lipid-lowering medications atorvastatin, pravastatin, and simvastatin to reduce cholesterol levels, have a relatively low risk of developing rhabdomyolysis, (a disorder that causes the breakdown of muscle), according to a new study in the December 1 issue of JAMA.

23 Nov 2004

Risk of a blocked vessel stroke increases nearly twofold in young women with a history of stroke

Young women with a family history of stroke in their parents or siblings may be at increased risk for stroke themselves, according to a new report.

23 Nov 2004

Capsules may be effective in treating bipolar disorder

University of North Carolina at Chapel Hill researchers have announced study results finding that a formulation of three-beaded extended-release carbamazepine capsules (ERC-CBZ) was effective, safe and tolerable in the treatment of bipolar I disorder

19 Nov 2004

FDA Vioxx fiasco raises questions about AIDS drug approvals for developing world

AIDS Healthcare Foundation (AHF), today noted that the current "FDA fiasco" involving the agency's initial approval and subsequent recall of Merck's troubled arthritis drug, Vioxx, raises serious questions about the FDA's ongoing parallel role in the approval of generic AIDS drugs for widespread use in Africa and the developing world.

19 Nov 2004

Computerized reminder systems increase influenza and pneumococcal vaccination rates

Computer-based standing orders are more effective than computerized reminders to physicians in increasing influenza and pneumococcal vaccine administration for hospitalized patients, according to an article in the November 17 issue of JAMA.

17 Nov 2004

Concord grapes increase good cholesterol

Drinking Concord grape juice significantly increased HDL--the good cholesterol--and significantly lowered two markers of inflammation in people with stable coronary artery disease, according to results of a study presented in the November issue of the journal Arteriosclerosis, Thrombosis and Vascular Biology.

16 Nov 2004

White Paper aims to reduce the number of people who smoke

Health Secretary John Reid today published Choosing Health – the Government’s White Paper on improving public health in England.

16 Nov 2004

Startling new blood pressure findings - atherosclerosis slowed

A new study led by The Cleveland Clinic shows that giving blood pressure lowering medication to heart disease patients with a “normal” blood pressure dramatically reduces risk of adverse cardiac events and slows disease progression.

16 Nov 2004

Keeping fit lowers C-Reactive protein in people with metabolic syndrome

In people with signs of metabolic syndrome, including high blood pressure, high triglycerides, high cholesterol, elevated blood glucose and obesity, physical activity appears to reduce a marker for inflammation which has been linked to heart disease

16 Nov 2004

Computer vignette effective at measuring quality of physician practice

A new measurement tool called the computerized clinical vignette can help clinicians and policymakers assess and improve the quality of physician practice while potentially reducing costs, according to a study led by a researcher at the San Francisco VA Medical Center (SFVAMC).

16 Nov 2004

Four major U.S. ethnic groups less likely to have cholesterol controlled

Compared with non-Hispanic whites, non-Hispanic blacks and Hispanics who qualify for cholesterol-lowering drug treatment are less likely to have their “bad” LDL cholesterol controlled to recommended levels, researchers reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

The cholesterol-lowering drug atorvastatin slowed down mental decline and improved depressive symptoms in people with Alzheimer’s disease, according to a small pilot study reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Metabolic syndrome associated with cognitive decline in elderly persons

Elderly individuals with the metabolic syndrome, a grouping of several common conditions including abdominal obesity, low level of high-density lipoprotein (HDL, the “good cholesterol”), hypertension, and high triglyceride and blood sugar levels, are more likely to experience cognitive impairment than those without this syndrome, according to a study in the November 10 issue of JAMA.

10 Nov 2004

Medicare to reimburse preventive cholesterol screening

As the nation's leading cardiologists gather for the American Heart Association's Scientific Sessions 2004, the Centers for Medicare & Medicaid Service (CMS) has announced the 2005 Physician Fee Schedule, which guarantees access to preventive cholesterol screenings for 39 million Medicare-eligible beneficiaries.

9 Nov 2004

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

Results from a new study showed that coadministration of Zetia (ezetimibe) and fenofibrate significantly reduced LDL ("bad") cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C) and apo B1 in patients with mixed hyperlipidemia and high LDL cholesterol when compared to fenofibrate alone.

9 Nov 2004

FDA has warned consumers not to purchase or to consume Actra-Rx or Yilishen, promoted as "dietary supplements" for treating erectile dysfunction

The Food and Drug Administration today warned consumers not to purchase or to consume Actra-Rx or Yilishen, two products promoted and offered for sale on Web sites as "dietary supplements" for treating erectile dysfunction and enhancing sexual performance for men.

9 Nov 2004

Cholesterol News and Research

Further Reading

Low-glycemic load diets may make dieting easier

Having diabetes raises a woman's risk of having a heart attack to nearly 10 times

Experimental compound prevents cholesterol gallstone disease

Information about serious adverse effects of cerivastatin were known within months after drug launched

Patients taking the lipid-lowering medications have a relatively low risk of developing rhabdomyolysis

Risk of a blocked vessel stroke increases nearly twofold in young women with a history of stroke

Capsules may be effective in treating bipolar disorder

FDA Vioxx fiasco raises questions about AIDS drug approvals for developing world

Computerized reminder systems increase influenza and pneumococcal vaccination rates

Concord grapes increase good cholesterol

White Paper aims to reduce the number of people who smoke

Startling new blood pressure findings - atherosclerosis slowed

Keeping fit lowers C-Reactive protein in people with metabolic syndrome

Computer vignette effective at measuring quality of physician practice

Four major U.S. ethnic groups less likely to have cholesterol controlled

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

Metabolic syndrome associated with cognitive decline in elderly persons

Medicare to reimburse preventive cholesterol screening

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

FDA has warned consumers not to purchase or to consume Actra-Rx or Yilishen, promoted as "dietary supplements" for treating erectile dysfunction

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