Genes News and Research

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Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer

Biomarker testing surveys specific disease-associated molecules to predict treatment response and disease progression; however its use has complicated the diagnosis of non-small-cell lung cancer (NSCLC).

15 Mar 2021

New cancer immunotherapy uses engineered T cells to target a common genetic alteration

Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers.

15 Mar 2021

Scientists discover how novel pathogens promote colorectal cancer development

Do BMMFs, the novel infectious agents found in dairy products and bovine sera, play a role in the development of colorectal cancer? Scientists led by Harald zur Hausen detected the pathogens in colorectal cancer patients in close proximity to tumors.

15 Mar 2021

MGH researchers uncover new clues about X chromosome inactivation

Researchers at Massachusetts General Hospital have uncovered new clues that add to the growing understanding of how female mammals, including humans, "silence" one X chromosome.

15 Mar 2021

Exercise during pregnancy can disrupt the vicious cycle of parents-to-child transmission of diseases

Exercise during pregnancy may let mothers significantly reduce their children's chances of developing diabetes and other metabolic diseases later in life, new research suggests.

15 Mar 2021

The role of nanotechnology in the fight against COVID-19

Appearing in the journal Nanomedicine, the review summarized all the exciting advances made using diverse nanomaterials (polymeric, inorganic self-assembling materials and peptide-based) towards COVID-19 prevention, diagnosis and therapy.

15 Mar 2021

Which biomarkers can help predict severe COVID-19?

The ability to detect potentially fatal illness early on in the course of the disease would enable a swift prioritization of these high-risk individuals for treatment. A new preprint on the medRxiv* server presents an array of biomarkers that may help achieve this laudable goal.

15 Mar 2021

Study shows evidence-based interventions can improve infant brain health

In the world of neurodevelopment, one thing is clear: the earlier the intervention the better. Infancy is a critical time in brain development, and neuroscientists are increasingly identifying factors that can negatively impact cognition and ones that can improve cognition early in life.

15 Mar 2021

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

In a recent bioRxiv preprint research paper, Botond Z. Igyártó and colleagues from Thomas Jefferson University demonstrated the inflammatory nature of the lipid nanoparticles (LNPs).

15 Mar 2021

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

In a methodologically trailblazing paper published in the journal Nature Genetics, a team of Belgian scientists uncovered an assembly of coronavirus host factors that may be exploited to develop drugs against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also potentially forthcoming zoonotic coronaviruses.

14 Mar 2021

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells.

14 Mar 2021

Novel computer-guided design tool helps increase the efficiency of cell conversions

There is a great need to generate various types of cells for use in new therapies to replace tissues that are lost due to disease or injuries, or for studies outside the human body to improve our understanding of how organs and tissues function in health and disease.

13 Mar 2021

Le Bonheur and UTHSC sign agreement to obtain genetic information from 25,000 DNA samples

As research into genetic causes of disease began to grow, Le Bonheur Pediatrician-in- Chief Jon McCullers, MD, knew it was time to start building a pediatric DNA biorepository.

13 Mar 2021

Random cellular changes play vital role in longevity beyond genetics and environment

A new model of aging takes into account not only genetics and environmental exposures but also the tiny changes that randomly arise at the cellular level.

13 Mar 2021

Research provides a new cornerstone of malaria's evolution with humans

New bioarchaeological research shows malaria has threatened human communities for more than 7000 years, earlier than when the onset of farming was thought to have sparked its devastating arrival.

13 Mar 2021

Impact of type I interferon (IFN) autoantibodies in critical COVID-19

A new preprint discusses the pathogenesis of this critical COVID-19 with reference to autoimmune phenomena involving the key antiviral type I interferon pathway.

12 Mar 2021

SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment, study finds

Researchers have found that SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment. Therefore, strategies such as focusing on limiting the production of IFN, rather than its function, could restrict the mechanism of SARS-CoV-2 that increases its viral load with delayed or absent symptoms.

12 Mar 2021

Genes News and Research

Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer

New cancer immunotherapy uses engineered T cells to target a common genetic alteration

Scientists discover how novel pathogens promote colorectal cancer development

MGH researchers uncover new clues about X chromosome inactivation

Exercise during pregnancy can disrupt the vicious cycle of parents-to-child transmission of diseases

The role of nanotechnology in the fight against COVID-19

Which biomarkers can help predict severe COVID-19?

Study shows evidence-based interventions can improve infant brain health

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

Novel computer-guided design tool helps increase the efficiency of cell conversions

Le Bonheur and UTHSC sign agreement to obtain genetic information from 25,000 DNA samples

Random cellular changes play vital role in longevity beyond genetics and environment

Research provides a new cornerstone of malaria's evolution with humans

Impact of type I interferon (IFN) autoantibodies in critical COVID-19

SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment, study finds

Novel tool can add or remove sugar from proteins

Deforestation in the Amazon increases diversity of antibiotic-resistant bacteria

Living in neighborhoods with high rates of violence and poverty alters gene activity

eBook: Using iPSCs models for human disease research and drug discovery eBook

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