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Study reveals the mechanism of common DNA mutations

Researchers at The Ohio University have uncovered the mechanism by which thymine and guanine, the most commonly mutated bases in DNA, become damaged.

2 Feb 2018

New ChIPseq kit is optimized for fresh and frozen tissue samples

The new, high-performance Chromatrap ChIP-Seq kit (v.1.5) is optimized to work from fresh and frozen extracted tissue, as well as cell lines.

From Chromatrap® - Porvair Sciences Ltd 2 Feb 2018

Study unravels developmental splicing program that promotes neuronal maturation

Neurons, or nerve cells, in the brain communicate with each other by transmitting electric signals, or firing action potentials, through long processes named axons (which send out signals) and dendrites (which receive signals).

1 Feb 2018

Two bacterial species collaborate to drive development of colon cancers

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy research team finds.

1 Feb 2018

Stealth gene shuttles open up new avenues to treat aggressive cancers

Viruses have their own genetic material and can infect human cells in a very specific manner. They will then reproduce as directed by their own genes but using the resources of the host cell.

31 Jan 2018

Discovery of molecular nets may lead to new treatment approach for heart failure

Local researchers have discovered that a group of molecules, called chondroitin sulfate, normally found only in connective tissues such as the cartilage, accumulates and causes inflammation in the hearts of patients with heart failure.

31 Jan 2018

Long-term intake of sunflower, fish oils affects the liver

An international group of scientists led by the University of Granada (UGR) has demonstrated that the long-term intake of sunflower or fish oils damages the liver and can cause a series of alterations in it, giving rise to non-alcoholic steatohepatitis.

31 Jan 2018

Study provides novel insights into evolutionary pathways of pancreatic cancer

Pancreatic cancer is a form of cancer associated with the highest mortality rates in the world. Genetic changes that could explain his aggressiveness and early metastasis had not been found yet.

30 Jan 2018

Researchers sequence human genome using pocket-sized device

Scientists have assembled the most complete human genome to date using a pocket-sized, portable DNA sequencer.

From Oxford Nanopore Technologies 30 Jan 2018

Muscles possess 'memory' of earlier growth at the DNA level, study shows

A study led by researchers at Keele University has shown for the first time that human muscles possess a 'memory' of earlier growth - at the DNA level.

30 Jan 2018

Role of genetics behind immune disease risk could be missed, scientists suggest

The role of genetics in the risk of having an immune disease could be missed in research, scientists suggest.

29 Jan 2018

My grandmother was Italian. Why aren’t my genes Italian?

Maybe you got one of those find-your-ancestry kits over the holidays. You’ve sent off your awkwardly collected saliva sample, and you’re awaiting your results.

29 Jan 2018

Viral replication process weak spot may help develop cure for infections

Researchers at the Morgridge Institute for Research believe they have identified a weak spot in the replication process of positive-strand RNA viruses, which could yield treatment for viral infections such as Zika, Polio, Chikungunya, Hepatitis C and even common cold viruses.

29 Jan 2018

Scientists decipher molecular mechanism of the cell with relevance for cancer development

Achievement in the field of cancer research: Biologists and chemists at the University of Konstanz decipher a molecular mechanism of the cell with relevance for the development of cancer and the fight against that disease.

27 Jan 2018

Global effort toward HIV cure published in Special Issue of AIDS Research and Human Retroviruses

Researchers have shown that despite effective combined antiretroviral therapy, HIV can hide in the spleen of patients with no detectable HIV in their blood.

27 Jan 2018

Discovery may offer new therapeutic approach for kids with Prader-Willi syndrome

Stem cell researchers at UConn Health have reversed Prader-Willi syndrome in brain cells growing in the lab, findings they recently published in the Human Molecular Genetics.

27 Jan 2018

Small tweak to mammal's DNA can cause significant physical changes, study finds

The difference between webbed toes and distinct digits may be the result of not just genetic information, but of how the genes regulate that information. Researchers at the National Institute of Genetics, Research Organization of Information and Systems in Japan found that a small, non-specific tweak to a mammal's DNA can potentially cause specific and significant physical changes.

27 Jan 2018