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New technology may offer alternative means of profiling tissues

Current cancer treatment courses often begin with tissue biopsies. Biopsies, however, which involve the physical resection of a small tissue sample, can lead to localized tissue injury, bleeding, inflammation, and stress, as well as increased risk of metastasis.

19 Nov 2019

CTF, DELopen jointly offer unique opportunities to neurofibromatosis research community

The Children's Tumor Foundation, an innovative and global neurofibromatosis (NF) research foundation announced today a collaboration with DELopen, a DNA-encoded library technology platform sponsored by WuXi AppTec, a leading global provider of R&D and manufacturing services enabling companies in the pharmaceutical, biotechnology and medical device industries.

19 Nov 2019

Rutgers Cancer Institute researchers awarded $2.3 million in American Cancer Society grants

More than $2.3 million in Research Scholar Grants from the American Cancer Society have been awarded to three Rutgers Cancer Institute of New Jersey researchers to examine cell metabolism and tumor formation in forms of breast cancer, lung cancer and leukemia.

19 Nov 2019

Surgery can improve survival rate for oldest patients with early stage lung cancer

Many patients with early stage lung cancer who are age 90 years and older do not receive treatment; however, surgery in this nonagenarian population should be considered because it could significantly increase the chances for 5-year survival, according to research published online today in The Annals of Thoracic Surgery.

19 Nov 2019

New drug combo may improve pancreatic cancer therapy

A new study by scientists at Sanford Burnham Prebys Medical Discovery Institute have discovered a combination of two cancer-fighting drugs that successfully worked on pancreatic tumor in mice, shrinking them significantly, and paving the way for a speedy clinical trial designed to test their efficacy in humans.

18 Nov 2019

Neural architecture search automates the development of deep learning-based models for cancer research

Argonne researchers have created a neural architecture search that automates the development of deep-learning-based predictive models for cancer data.

18 Nov 2019

'Dysbiosis' promotes the onset of colorectal cancer

The gastroenterology team at Henri-Mondor AP-HP Hospital and University Paris-Est Créteil, led by Professor Iradj Sobhani, together with teams from Inserm and the Institut Pasteur Molecular Microbial Pathogenesis Unit (U1202), led by Professor Philippe Sansonetti - holder of the Microbiology and Infectious Diseases Chair at the Collège de France -, have demonstrated that an imbalance in the gut microbiota, also known as "dysbiosis", promotes the onset of colorectal cancer.

18 Nov 2019

Research breakthrough may lead to new therapeutic targets for cancers

Computational modeling is the use of computers to simulate and study the behavior of complex systems. Computational approaches are widely adopted in the bioimedical sciences and can be used to sift through large volumes of complex data to extract recurrent patterns that may point to a disease's causes and effects.

15 Nov 2019

New mathematical model uses primary tumor size to predict metastasis

A new mathematical model uses the size of a cancer patient’s initial, primary tumor to predict whether undetectable secondary tumors are already present. Stefano Avanzini and Tibor Antal of the University of Edinburgh, U.K., present the model in PLOS Computational Biology.

15 Nov 2019

Research explains why immunotherapy fails against prostate cancer bone metastases

Prostate cancer that spreads to the bone triggers the destruction of bone tissue that, in turn, thwarts the effectiveness of immune checkpoint inhibitors by blocking the development of T cells that are crucial to successful treatment, researchers from The University of Texas MD Anderson Cancer Center report in Cell.

14 Nov 2019

Lithium corrects radiation damage to brain in young cancer patients

A new study on mice, published online in the journal Molecular Psychiatry, on November 14, 2019, shows that the intermittent use of lithium, which is widely used to stabilize the mood in conditions such as bipolar disorder, can correct memory and learning losses due to radiation therapy to the brain in very young animals, even when the lithium is given long after the injury.

14 Nov 2019

Inhaled nanoparticles can help treat lung cancer

Scientists have reported a new approach to treating lung cancer with inhaled nanoparticles developed at Wake Forest School of Medicine, part of Wake Forest Baptist Health.

14 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Study on sea sponge opens up possibilities to create new antitumor drugs

Chemists from Far Eastern Federal University's School of Natural Sciences developed a new method to synthesize biologically active derivatives of fascaplysin -- cytotoxic pigment of a sea sponge. For the first time, they got a sufficient amount of 3-bromofascaplysin and 3,10-dibromofascaplysin, which were known before but were not available for study.

14 Nov 2019

FDA grants acceptance to application for selumetinib as treatment for neurofibromatosis

AstraZeneca and MSD (Merck) announced today that the U.S. Food and Drug Administration (FDA) has granted acceptance to file status of its application for the MEK inhibitor selumetinib, for use in patients with plexiform neurofibromas, a common manifestation in the disease neurofibromatosis type one (NF1).

14 Nov 2019

Blocking metastasis-promoting enzyme can prevent spread of breast cancer

In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.

14 Nov 2019

Knocking out 'survival system' of cancer cells could improve effectiveness of melanoma treatment

The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the 'survival system' of cancer cells according to a study published in Nature Communications today.

14 Nov 2019

Cedars-Sinai surgeons detect and remove 25-pound cancerous ovarian tumor

Maria Robles Garcia was sure her uncomfortable abdominal symptoms weren't caused by irritable bowel syndrome or from being overweight, no matter that her local doctors repeatedly told her that was the case.

13 Nov 2019

Secondary surgery for recurrent ovarian cancer patients does not result in longer survival

Researchers from The University of Texas MD Anderson Cancer Center reported that secondary tumor-reduction, or cytoreduction, surgery followed by chemotherapy did not result in longer survival than chemotherapy alone in patients with platinum-sensitive recurrent ovarian cancer.

13 Nov 2019

New biomarker discovered in cancer stem cells

In the world of cancer biology, not all biomarkers are created equal. These molecules that alert doctors that an abnormal process may be underway can appear as an array of aberrant proteins, such as hormones, enzymes or signaling molecules, and vary from patient to patient. Because they are a mixed bag, no one drug exists to attack them.

13 Nov 2019

Tumor News and Research

New technology may offer alternative means of profiling tissues

CTF, DELopen jointly offer unique opportunities to neurofibromatosis research community

Rutgers Cancer Institute researchers awarded $2.3 million in American Cancer Society grants

Surgery can improve survival rate for oldest patients with early stage lung cancer

New drug combo may improve pancreatic cancer therapy

Neural architecture search automates the development of deep learning-based models for cancer research

'Dysbiosis' promotes the onset of colorectal cancer

Research breakthrough may lead to new therapeutic targets for cancers

New mathematical model uses primary tumor size to predict metastasis

Research explains why immunotherapy fails against prostate cancer bone metastases

Lithium corrects radiation damage to brain in young cancer patients

Inhaled nanoparticles can help treat lung cancer

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Study on sea sponge opens up possibilities to create new antitumor drugs

FDA grants acceptance to application for selumetinib as treatment for neurofibromatosis

Blocking metastasis-promoting enzyme can prevent spread of breast cancer

Knocking out 'survival system' of cancer cells could improve effectiveness of melanoma treatment

Cedars-Sinai surgeons detect and remove 25-pound cancerous ovarian tumor

Secondary surgery for recurrent ovarian cancer patients does not result in longer survival

New biomarker discovered in cancer stem cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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