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Research uncovers novel anti-craving mechanism to treat cocaine relapse

Cocaine continues to be one of the most commonly abused illicit drugs in the United States. Pre-clinical literature suggests that targeting glucagon-like peptide-1 receptors (GLP-1Rs) in the brain may represent a novel approach to treating cocaine use disorder.

7 Dec 2020

How effective is social distancing in preventing SARS-CoV-2 transmission? A New York case study

A new study by researchers at the City University of Hong Kong examined the efficacy of non-pharmaceutical interventions (NPIs) on controlling the coronavirus disease 2019 (COVID-19) pandemic, the illness SARS-CoV-2 causes.

7 Dec 2020

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

A team of researchers at the Feinberg School of Medicine demonstrated that xylitol and grapefruit seed extract (GSE) could prevent SARS-CoV-2 infection. These can be used as a nasal spray to contain the spread of the coronavirus.

7 Dec 2020

The intranasal route of immunization may offer effective protection against SARS-CoV-2

Researchers at the School of Medicine, Washington University in Saint Louis, USA, showed that the intranasal route of immunization could provide a more efficient protection against SARS-CoV-2 compared to the intramuscular route (i.e. through ‘jabs’).

7 Dec 2020

No evidence for risk of vaccine-driven virulence evolution in SARS-CoV-2

Beyond the morbidity and mortality associated with the pandemic, COVID-19 has paralyzed the global economy.

7 Dec 2020

Novel modular design approach to antibody nanocage generation

A new study shows the benefits of using computational design to create antibody nanocages that have the required orientation.

7 Dec 2020

Failure to comply with COVID-19 containment measures penalizes the compliant as well

The COVID-19 pandemic is now in its second wave and deaths are surpassing the spring peak as winter sets in over much of the northern hemisphere.

7 Dec 2020

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

A new study indicates that the topoisomerase 1 (Top1) is intimately related to the lethal inflammation associated with SARS-CoV-2 infection in a large proportion of cases.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Clonal hematopoiesis can confer a health benefit in allogeneic transplants

Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer.

7 Dec 2020

Los Robles enrolls first patient in landmark trial for treatment of chronic subdural hematoma

Los Robles Health System is leading the way in neurovascular clinical trials enrolling the first patient in the nation in STEM, the Squid trial for the treatment of chronic subdural hematoma (cSDH).

5 Dec 2020

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

Since the novel coronavirus emerged at the end of last year, scientists around the world -- including Beth Israel Deaconess Medical Center (BIDMC) immunologist Dan Barouch, MD, PhD -- have been developing vaccines to protect against COVID-19 and to put an end to the global pandemic.

5 Dec 2020

Efficacy News and Research

Research uncovers novel anti-craving mechanism to treat cocaine relapse

How effective is social distancing in preventing SARS-CoV-2 transmission? A New York case study

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

The intranasal route of immunization may offer effective protection against SARS-CoV-2

No evidence for risk of vaccine-driven virulence evolution in SARS-CoV-2

Novel modular design approach to antibody nanocage generation

Failure to comply with COVID-19 containment measures penalizes the compliant as well

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Clonal hematopoiesis can confer a health benefit in allogeneic transplants

Los Robles enrolls first patient in landmark trial for treatment of chronic subdural hematoma

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

Is mask-wearing effective in preventing SARS-CoV-2 transmission?

New CRISPR-Cas9 variant improves efficiency of gene editing tool

Can melatonin help prevent severe COVID-19?

Scientists develop new bioinformatics pipeline to identify viruses in environmental samples

Pomegranate extract could inhibit the virus that causes COVID-19

Novel “multitope” vaccine shows promise in the fight against COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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