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Intake of Bimuno in early life benefits brain development

Clasado Biosciences Limited, the producers and suppliers of Bimuno® (B-GOS), a unique patented trans-galactooligosaccharide complex, and the Department of Psychiatry, University of Oxford, today announce the results of their latest pre-clinical study, demonstrating for the first time a major role of B-GOS in modulating brain development at the molecular level in early life stages.

11 Jan 2016

UTA researchers map out chemical mechanism of key enzyme found in autism, Alzheimer's and Down syndrome

Biochemists at The University of Texas at Arlington are mapping the catalytic processes of sulfur-oxidizing enzymes to improve understanding of the chemical imbalances found in patients with autism, Alzheimer's disease and Down syndrome.

11 Jan 2016

U-M research could lead to new ways of fighting X-linked diseases in girls and women

Nearly every girl and woman on Earth carries two X chromosomes in nearly every one of her cells -- but one of them does (mostly) nothing. That's because it's been silenced, keeping most of its DNA locked up and unread like a book in a cage.

11 Jan 2016

Researchers reveal specific enzyme responsible for sensing energy source that fuels growth of cancer cells

An international research team formed by a University of Cincinnati cancer researcher has shown for the first time that a specific enzyme is responsible for sensing the available supply of GTP, an energy source that fuels the uncontrolled growth of cancer cells. The research underscores the enzyme's potential to become a therapeutic target for future cancer drugs.

11 Jan 2016

NUS-led study discovers potential therapeutic approach against colorectal cancer

A study led by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has demonstrated the efficiency of a small molecule drug, PRIMA-1met, in inhibiting the growth of colorectal cancer cells. Colorectal cancer is the cancer of the large intestine (colon and rectum) and is the most common cancer in Singapore.

11 Jan 2016

Anthony Nolan introduces new tissue typing method that could revolutionise stem cell transplantation

Anthony Nolan has today launched a new tissue typing method that could significantly improve stem cell transplant outcomes.

8 Jan 2016

DNA damage may lead to mutation and changes in cell

A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly damaged by things from the outside environment, like sunlight, cigarette smoke and radiation. However, more recently researchers have discovered that sources from within the cell itself can sometimes be even more damaging.

7 Jan 2016

Jubilant Biosys, Sanofi partner to develop small molecule inhibitors in metabolic disorders therapeutic area

Jubilant Biosys Ltd, a Bengaluru-based subsidiary of Jubilant Life Sciences Ltd, and Sanofi Deutschland GmbH, Frankfurt, Germany, announced a strategic alliance to discover and develop small molecule inhibitors for multiple targets in the metabolic disorders therapeutic area.

7 Jan 2016

Combining NELL-1 with BMP2 therapy may promote bone development

Bone morphogenetic protein-2 (BMP2) is used clinically to promote bone repair. However, the high BMP2 concentrations required to stimulate bone growth in humans may produce life-threatening adverse effects such as cervical swelling in spinal fusion procedures, a problem that prompted an FDA warning in 2008.

7 Jan 2016

DURECT reports successful completion of DUR-928 Phase 1 study for acute use indications

DURECT Corporation today announced the successful completion of a Phase 1 clinical trial with an injectable formulation of DUR-928 intended for acute use indications. DUR-928 is an endogenous, small-molecule, new chemical entity (NCE), which may have broad applicability in metabolic diseases such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), and in acute organ injuries such as acute kidney injury (AKI).

6 Jan 2016

Lipoprotein nanoplatelets important for imaging biological molecules and cells

An interdisciplinary research team from the University of Illinois at Urbana-Champaign has developed a new material composite derived from quantum dots. These lipoprotein nanoplatelets are rapidly taken up by cells and retain their fluorescence, making them particularly well-suited for imaging cells and understanding disease mechanisms.

6 Jan 2016

FDA permits Sound Pharmaceuticals to start SPI-1005 clinical trial for treatment of Meniere's Disease

Sound Pharmaceuticals is pleased to announce that it began enrolling a clinical trial to test SPI-1005 in the treatment of Meniere's Disease (MD). MD or idiopathic endolymphatic hydrops is an inner ear disease that involves episodic vertigo, sensorineural hearing loss, and tinnitus.

5 Jan 2016

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on gastrointestinal and cardio-renal diseases, today announced positive results of an open label clinical study evaluating the pharmacodynamic (PD) activity of RDX022 in healthy adult volunteers.

5 Jan 2016

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

My laboratory’s long standing interest is the study of the signaling capabilities of stem cells, both under homeostatic conditions

From Beckman Coulter Life Sciences - Flow Cytometry 5 Jan 2016

New study describes STING protein's role in potential suppression of colorectal cancer

A new study published today by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine reports on a key finding about the immune system's response to tumor development following studies on colorectal cancer.

4 Jan 2016

Novel imaging-based method as accurate as current standard-of-care for breast cancer treatment

A new study shows that a novel imaging-based method for defining appropriateness of breast cancer treatment is as accurate as the current standard-of-care and could reduce the need for invasive tissue sampling. The results suggest that the method might lead to more optimal treatment of individual patients.

31 Dec 2015

Researchers use dynamic time-series data to help improve accuracy of genome mapping

If you already have the sequenced map of an organism's genome but want to look for structural oddities in a sample, you can check the genomic barcode -- a series of distances between known, targeted sites -- by cutting a DNA sequence at those sites and examining the distance between the cuts.

30 Dec 2015

ORNL's cell-free protein synthesis system can help save lives of soldiers injured in remote locations

Lives of soldiers and others injured in remote locations could be saved with a cell-free protein synthesis system developed at the Department of Energy's Oak Ridge National Laboratory.

30 Dec 2015

Infusing small dose of cytokine can prevent or reverse diabetes-related kidney failure

Diabetes is the leading cause of kidney failure, and scientists have found that infusing just a small dose of a cytokine, thought to help cause that failure, can instead prevent or reverse it.

29 Dec 2015

Researchers identify new gene that helps maintain chromosome number in cells

Molecular biologists at UT Southwestern Medical Center have identified a gene called NORAD that helps maintain the proper number of chromosomes in cells, and that when inactivated, causes the number of chromosomes in a cell to become unstable, a key feature of cancer cells.

26 Dec 2015

Molecule News and Research

Intake of Bimuno in early life benefits brain development

UTA researchers map out chemical mechanism of key enzyme found in autism, Alzheimer's and Down syndrome

U-M research could lead to new ways of fighting X-linked diseases in girls and women

Researchers reveal specific enzyme responsible for sensing energy source that fuels growth of cancer cells

NUS-led study discovers potential therapeutic approach against colorectal cancer

Anthony Nolan introduces new tissue typing method that could revolutionise stem cell transplantation

DNA damage may lead to mutation and changes in cell

Jubilant Biosys, Sanofi partner to develop small molecule inhibitors in metabolic disorders therapeutic area

Combining NELL-1 with BMP2 therapy may promote bone development

DURECT reports successful completion of DUR-928 Phase 1 study for acute use indications

Lipoprotein nanoplatelets important for imaging biological molecules and cells

FDA permits Sound Pharmaceuticals to start SPI-1005 clinical trial for treatment of Meniere's Disease

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

New study describes STING protein's role in potential suppression of colorectal cancer

Novel imaging-based method as accurate as current standard-of-care for breast cancer treatment

Researchers use dynamic time-series data to help improve accuracy of genome mapping

ORNL's cell-free protein synthesis system can help save lives of soldiers injured in remote locations

Infusing small dose of cytokine can prevent or reverse diabetes-related kidney failure

Researchers identify new gene that helps maintain chromosome number in cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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