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SARS-CoV-2 RNA and antibody detection in infected mothers’ breast milk

In a recent study published in the Journal of Medical Virology, Italian researchers investigated the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) and antibodies (Abs) in the milk of breastfeeding mothers with SARS-CoV-2 infections.

14 Sep 2022

Large molecules glom together into dense droplets to create squishy circuits in cells

An emerging field explores how groups of molecules condense together inside cells, the way oil droplets assemble and separate from water in a vinaigrette.

14 Sep 2022

Customized bivalent mRNA COVID boosters protect against BA.5 Omicron variant

In a recent study posted to the bioRxiv* pre-print server, researchers from Washington University School of Medicine, Moderna, Inc, and the U.S. National Institutes of Health tested two bivalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines based on the messenger ribonucleic acid (mRNA) platform.

14 Sep 2022

Scientists harness the potential of bacteria to help create synthetic cells with lifelike functionality

Scientists have harnessed the potential of bacteria to help build advanced synthetic cells which mimic real life functionality.

14 Sep 2022

Walnut consumption early on in life may lead to better health as we age

Researchers who reviewed 20 years of diet history and 30 years of physical and clinical measurements have found participants who ate walnuts early on in life showed a greater likelihood for being more physically active, having a higher quality diet, and experiencing a better heart disease risk profile as they aged into middle adulthood.

14 Sep 2022

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

In a new study, researchers investigated the interactions between sirtuin 5 (SIRT5) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein (Nsp14) protein.

14 Sep 2022

What is the impact of COVID-19 treatments targeting intracellular Neu1?

In a new study, researchers assessed the impact of targeting intracellular Neu1 on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib remain poorly understood. In this study, we demonstrated, for the first time, that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells.

14 Sep 2022

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

In a recent study published in the journal eBioMedicine, researchers in Denmark and Sweden administered a cationic liposome-adjuvanted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit vaccine as a subcutaneous (s.c.) prime-intranasal (i.n.) boost strategy to elicit mucosal immune responses among SARS-CoV-2-infected Syrian hamsters.

14 Sep 2022

Manuka honey could cure serious lung infections caused by drug-resistant bacterium

In a recent study published in the journal Microbiology, researchers demonstrated that incorporating Manuka honey into nebulized antibiotic treatment could effectively combat respiratory infections due to Mycobacterium abscessusus, offering a novel new therapeutic strategy for M. abscessus management.

13 Sep 2022

MIT researchers use new technique to gather insight into repetitive protein sequences

About 70 percent of all human proteins include at least one sequence consisting of a single amino acid repeated many times, with a few other amino acids sprinkled in. These "low-complexity regions" are also found in most other organisms.

13 Sep 2022

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Researchers at Oregon State University and Oregon Health & Science University have developed a promising, first-of-its-kind messenger RNA therapy for ovarian cancer as well as cachexia, a muscle-wasting condition associated with cancer and other chronic illnesses.

13 Sep 2022

Efficacy and safety of monoclonal antibodies against SARS-CoV-2 during pregnancy

In an article published in the journal Expert Opinion on Drug Safety, scientists have described the safety and efficacy profiles of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monoclonal antibodies in pregnant women with coronavirus disease 2019 (COVID-19).

13 Sep 2022

New drug marks cancer cells for destruction by the immune system

Tumor cells are notoriously good at evading the human immune system; they put up physical walls, wear disguises and handcuff the immune system with molecular tricks.

13 Sep 2022

Review highlights the role of retinol-binding protein-4 in non-alcoholic fatty liver disease

It is a known fact that consuming a large amount of alcohol, even for a few days, triggers fat accumulation in the liver and ultimately leads to alcohol-related liver diseases.

13 Sep 2022

Experimental drug prolongs survival, improves muscle function in mice severe Duchenne muscular dystrophy

Researchers at Johns Hopkins Medicine report that an experimental drug first developed to treat kidney disease prolongs survival and improves muscle function in mice genetically engineered to develop a severe form of Duchenne muscular dystrophy (DMD).

13 Sep 2022

In vitro skeletal muscle models could lead to personalized medicine for type 2 diabetes

Abnormally high blood sugar (glucose) levels can result in Type 2 diabetes when things go awry with the body's skeletal muscle, which plays a key role in regulating glucose.

13 Sep 2022

Study shows vaccine-derived poliovirus in infant with severe immunodeficiency

Researchers identified type 3 vaccine-derived poliovirus (VDPV) in an infant.

13 Sep 2022

Researchers join forces to 'map' specific variations in more than 25 key cardiac disease genes

One in 100 people have genetic variations that can cause potentially life-threatening heart conditions, including high cholesterol (lipid disorders), heart muscle disease (cardiomyopathies), and abnormal heart rhythms (arrhythmias).

13 Sep 2022

Brain organoids shed light into the evolution of the human brain

Animal studies on great apes have long been banned in Europe for ethical reasons. For the question pursued here, so-called organoids, i.e. three-dimensional cell structures a few millimeters in size that are grown in the laboratory, are an alternative to animal experiments.

13 Sep 2022

Protein C News and Research

SARS-CoV-2 RNA and antibody detection in infected mothers’ breast milk

Large molecules glom together into dense droplets to create squishy circuits in cells

Customized bivalent mRNA COVID boosters protect against BA.5 Omicron variant

Scientists harness the potential of bacteria to help create synthetic cells with lifelike functionality

Walnut consumption early on in life may lead to better health as we age

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

What is the impact of COVID-19 treatments targeting intracellular Neu1?

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

Manuka honey could cure serious lung infections caused by drug-resistant bacterium

MIT researchers use new technique to gather insight into repetitive protein sequences

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Efficacy and safety of monoclonal antibodies against SARS-CoV-2 during pregnancy

New drug marks cancer cells for destruction by the immune system

Review highlights the role of retinol-binding protein-4 in non-alcoholic fatty liver disease

Experimental drug prolongs survival, improves muscle function in mice severe Duchenne muscular dystrophy

In vitro skeletal muscle models could lead to personalized medicine for type 2 diabetes

Study shows vaccine-derived poliovirus in infant with severe immunodeficiency

Researchers join forces to 'map' specific variations in more than 25 key cardiac disease genes

Brain organoids shed light into the evolution of the human brain

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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