Clinical Trial News and Research

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Novartis partners with UC Berkeley to pursue 'undruggable' disease targets

Novartis has joined forces with researchers from the University of California, Berkeley, to develop new technologies for the discovery of next-generation therapeutics, pursuing the vast number of disease targets in cancer and other illnesses that have eluded traditional small-molecule compounds and are considered "undruggable."

28 Sep 2017

Study: Breast cancer clinical trials fail to establish control arm that meets current standard of care

Historically, randomized controlled trials have served as the state-of-the-art method for determining the efficacy and safety of new, innovative treatment regimens for patients with cancer and other diseases.

28 Sep 2017

Clinical trial demonstrates safety, efficacy of focused ultrasound to treat pediatric osteoid osteoma

Karun Sharma, MD, PhD, Director of Interventional Radiology, and colleagues at Sheikh Zayed Institute for Pediatric Surgical Innovation at Children's National Health System in Washington, DC, have completed their clinical trial to treat benign but painful bone tumors (osteoid osteoma) in children.

27 Sep 2017

FAU neuroscientist develops innovative program to prevent dementia

More than 5 million Americans today are affected by Alzheimer's disease (AD). If nothing is done to stop this upward trajectory, there will be more than 16 million people with AD in the United States and more than 60 million people with AD worldwide by 2050.

27 Sep 2017

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Merck KGaA, Darmstadt, Germany, and Pfizer Inc. today announced that the Japanese Ministry of Health, Labor, and Welfare (MHLW) has approved BAVENCIO (avelumab, genetically recombinant Injection 200mg/mL for intravenous use) as the first and only treatment indicated for curatively unresectable Merkel cell carcinoma (MCC), a rare and aggressive cancer, in Japan.

27 Sep 2017

Genetic testing can improve safety of common blood thinner, study shows

Warfarin is a blood thinner that is commonly prescribed to patients to prevent life-threatening blood clots. Despite its longtime use, warfarin remains tricky to dose because a person's genetic makeup influences how the drug is processed in the body.

27 Sep 2017

Trial identifies genetic fault that affects treatment response in leukemia patients

A genetic fault has been identified in people with an aggressive type of leukemia that can significantly affect how they respond to treatment.

27 Sep 2017

Drug combination produces synergistic effect against growth of triple-negative breast cancer

In the hunt for novel treatments against an aggressive form of breast cancer, researchers combined a new protein inhibitor with a chemotherapy drug to create a powerful combination that resulted in cancer cell death.

26 Sep 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

Review finds no increased cancer risk for people taking oral diabetes medication

People taking a new oral medication for Type 2 diabetes can breathe a sigh of relief concerning suspicions they might be at an increased risk for many types of cancer, according to Indiana University researchers.

26 Sep 2017

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Inspired by the Labyrinth of Greek mythology, a new chip etched with fluid channels sends blood samples through a hydrodynamic maze to separate out rare circulating cancer cells into a relatively clean stream for analysis. It is already in use in a breast cancer clinical trial.

21 Sep 2017

Novel gene therapy can inhibit, reverse multiple sclerosis in mouse models

Multiple sclerosis can be inhibited or reversed using a novel gene therapy technique that stops the disease's immune response in mouse models, University of Florida Health researchers have found.

21 Sep 2017

Wayne State research finds novel psychological therapy to be helpful for people with fibromyalgia

A novel psychological therapy that encourages addressing emotional experiences related to trauma, conflict and relationship problems has been found helpful for people with the chronic pain condition fibromyalgia.

21 Sep 2017

New sickle cell disease poll dispels long-held perceptions of African Americans

Pfizer Inc., the National Newspaper Publishers Association, and scholars from Howard University today announced results from a new national poll designed to deepen understanding and gauge perceptions around sickle cell disease (SCD) among African Americans.

21 Sep 2017

Study opens new door to potential treatments for highly lethal brain tumors

New research conducted in mice provides evidence that highly lethal brain tumors, called high-grade gliomas, stop growing when deprived of a specific molecule naturally produced when brain cells fire.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

Trial shows safety and tolerability of antisense oligomer for treatment of influenza A

A phase 1 clinical trial published in the British Journal of Clinical Pharmacology found that radavirsen -- an antisense oligomer that inhibits the production of certain influenza proteins -- is safe and well-tolerated in healthy individuals.

20 Sep 2017

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

In a multi-institutional collaborative study, scientists at The Wistar Institute and the Medical University of Vienna, Austria, have identified the role of tumor-infiltrating or tumor-associated B-cells ("TABs") in melanoma progression and resistance to targeted therapy.

20 Sep 2017

Research finds postpartum depressive symptoms in 45% of parents when newborns leave NICU

Almost half of parents whose children were admitted to Children's National Health System's neonatal intensive care unit experienced postpartum depressive symptoms, anxiety, and stress when their newborns were discharged from the hospital.

15 Sep 2017

Study suggests magnesium cream could be used to combat deficiencies

A new study by the University of Hertfordshire has revealed that a magnesium cream could be used as an alternative to tablets to combat major health problems including high blood pressure which are linked with deficiency.

From BetterYou Ltd 15 Sep 2017

Clinical Trial News and Research

Novartis partners with UC Berkeley to pursue 'undruggable' disease targets

Study: Breast cancer clinical trials fail to establish control arm that meets current standard of care

Clinical trial demonstrates safety, efficacy of focused ultrasound to treat pediatric osteoid osteoma

FAU neuroscientist develops innovative program to prevent dementia

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Genetic testing can improve safety of common blood thinner, study shows

Trial identifies genetic fault that affects treatment response in leukemia patients

Drug combination produces synergistic effect against growth of triple-negative breast cancer

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Review finds no increased cancer risk for people taking oral diabetes medication

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Novel gene therapy can inhibit, reverse multiple sclerosis in mouse models

Wayne State research finds novel psychological therapy to be helpful for people with fibromyalgia

New sickle cell disease poll dispels long-held perceptions of African Americans

Study opens new door to potential treatments for highly lethal brain tumors

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

Trial shows safety and tolerability of antisense oligomer for treatment of influenza A

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

Research finds postpartum depressive symptoms in 45% of parents when newborns leave NICU

Study suggests magnesium cream could be used to combat deficiencies

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