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A mutant SARS-CoV-2 subspecies from minks may evade antibody detection

In a recent research letter published on the bioRxiv preprint server, scientists from Japan discovered that the mutation of spike glycoprotein in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) derived from farmed minks can also be found in the group of individuals with coronavirus disease (COVID-19) and subsequently evade detection by our immune system.

30 Nov 2020

Virus induced lymphocytes show promise for COVID-19 and future pandemics

Researchers in the United States have conducted a study demonstrating the potential of a novel therapeutic approach to treating coronavirus disease 2019 (COVID-19). The therapy augments the body’s T cell response to the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by providing a boost of rapidly expanded virus-specific T cells.

30 Nov 2020

Mollusc-derived compounds potential medicines for COVID-19 and other respiratory diseases

A research team has reviewed the existing literature on compounds derived from molluscs used for treating respiratory diseases.

30 Nov 2020

What are the risks associated with human challenge trials for SARS-CoV-2 vaccine candidates?

Researchers from the University of Haifa, Israel, and WAW Statistical Consulting Ltd, UK, designed a model that helps determine the risks faced by participants in a hypothetical COVID-19 dosing study.

30 Nov 2020

IPM announces WHO's prequalification of dapivirine ring to reduce women’s HIV risk

The nonprofit International Partnership for Microbicides is pleased to announce the World Health Organization's prequalification of the dapivirine ring, a monthly vaginal ring to reduce women's HIV risk.

30 Nov 2020

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

Are SARS-CoV-2 protease inhibitors effective antivirals in treating COVID-19?

Many antiviral development studies have focused on the possibility of inhibiting the main viral protease (Mpro), and papain-like protease (PLpro), given their central role in viral replication. A new study draws attention to the high odds that these may not have anti-infective activity because of the redundant pathways present in human host cells.

30 Nov 2020

Steam inhalation therapy found to inactivate SARS-CoV-2 virions

Researchers have published a study on the efficacy of steam inhalations as another possible treatment to help mitigate SARS-CoV-2 infection.

30 Nov 2020

Resveratrol shows potential as SARS-CoV-2 antiviral, study finds

A recent study reveals that resveratrol, a phenolic compound produced by spermatophytes, can inhibit the viral replication SARS-CoV-2.

27 Nov 2020

SARS-CoV-2 spike protein shows slow but stable evolution, study finds

A new preprint published in November 2020 describes the seven different clades into which the virus has diversified.

27 Nov 2020

Monoclonal antibody HB27 shows potent neutralizing activity against SARS-CoV-2

A new study reports a very promising anti-SARS-CoV-2 monoclonal antibody, HB27, that appears to have two distinct mechanisms of action inhibiting the virus-host cell interaction and subsequent infection.

27 Nov 2020

N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

Researchers from the Harbin Institute of Technology, China, modeled the complexes formed between the RBD and the human ACE2 and monoclonal antibodies.

27 Nov 2020

Combining cell engineering with machine learning to design living medicines for cancer

Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research.

26 Nov 2020

Transgenic mouse model could recapitulate severe COVID-19 in humans

Researchers in the United States and Canada have described the potential for a transgenic mouse model to serve as an effective platform for the study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe disease course in humans.

26 Nov 2020

SARS-CoV-2 immunity can sustain for at least eight months, study finds

A new study by researchers at Monash University, Australia, has revealed that people who have been infected with COVID-19 showed sustained protection against reinfection for at least eight months.

26 Nov 2020

Novel CAR T-cell therapy shows promising early results in children with neuroblastoma

A novel CAR T-cell therapy developed by researchers at UCL and designed to target cancerous tumors, has shown promising early results in children with neuroblastoma, a rare form of childhood cancer.

25 Nov 2020

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

In a recent cutting-edge study, US researchers unveiled an anti-staphylococcal enterotoxin B monoclonal antibody that can be repurposed to target the cleavage site of the SARS-CoV-2 spike glycoprotein and, in turn, inhibit viral infection. Their findings are currently available on bioRxiv preprint server.

25 Nov 2020

Efficacy News and Research

A mutant SARS-CoV-2 subspecies from minks may evade antibody detection

Virus induced lymphocytes show promise for COVID-19 and future pandemics

Mollusc-derived compounds potential medicines for COVID-19 and other respiratory diseases

What are the risks associated with human challenge trials for SARS-CoV-2 vaccine candidates?

IPM announces WHO's prequalification of dapivirine ring to reduce women’s HIV risk

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

Are SARS-CoV-2 protease inhibitors effective antivirals in treating COVID-19?

Steam inhalation therapy found to inactivate SARS-CoV-2 virions

Resveratrol shows potential as SARS-CoV-2 antiviral, study finds

SARS-CoV-2 spike protein shows slow but stable evolution, study finds

Monoclonal antibody HB27 shows potent neutralizing activity against SARS-CoV-2

N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

Combining cell engineering with machine learning to design living medicines for cancer

Transgenic mouse model could recapitulate severe COVID-19 in humans

SARS-CoV-2 immunity can sustain for at least eight months, study finds

Novel CAR T-cell therapy shows promising early results in children with neuroblastoma

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

Iron infusion highly effective to treat anemia in low-income settings

Convalescent plasma therapy ineffective in treating severe COVID-19, study finds

Researchers explore prevention measures for SARS-CoV-2 transmission during international travel

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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