Clinical Trial News and Research

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FDA permits first digital therapeutic device for treatment of substance use disorders

The United States Food and Drug Administration (US FDA) yesterday – 14th of September 2017, permitted the marketing of an application developed for mobiles that would help in the treatment of substance use disorders (SUD).

14 Sep 2017

FDA grants accelerated approval to new drug for treating relapsed follicular lymphoma

The U.S. Food and Drug Administration today granted accelerated approval to Aliqopa (copanlisib) for the treatment of adults with relapsed follicular lymphoma who have received at least two prior treatments known as systemic therapies.

14 Sep 2017

Patients diagnosed with glioblastoma benefit from care at high-volume centers, study suggests

Patients diagnosed at high-volume centers are up to 40 percent more likely to receive treatment for glioblastoma, according to a study from researchers at the University of Illinois at Chicago.

14 Sep 2017

New clinical trial begins testing Epigem’s instrument for detection, cure of rare anemias

Epigem today announced that one of its development instruments, MeChem, is being tested in a new clinical trial into the detection and cure of rare anemias. The company has filed two patents relating to the test methods and the associated system.

14 Sep 2017

Clinical trial evaluates key-hole and open surgery in pancreatic cancer patients

A randomized clinical trial has compared key-hole (laparoscopic) surgery and open surgery in pancreatic cancer patients undergoing pancreaticoduodenectomy, or the Whipple procedure.

14 Sep 2017

Michigan Medicine researchers receive $3.5m to combat fatigue in MS patients

A new clinical trial will explore three interventions in improving one of the most disabling symptoms for people with multiple sclerosis: fatigue.

14 Sep 2017

Modified blood thinner may be first promising method to prevent repercussions after TBI

A chemically modified version of the common blood thinner heparin may be the first promising method of preventing the harmful cascade of destruction to brain tissue that commonly follows traumatic brain injury (TBI), according to new research findings.

13 Sep 2017

Researchers overcome major stumbling blocks in developing HIV vaccine

An international team of researchers has demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV: the ability to generate immune cells that stay in circulation long enough to respond to and stop virus infection.

13 Sep 2017

Combination immunotherapy shows better overall survival in kidney cancer patients

A combination immunotherapy treatment showed better overall survival in patients with previously untreated advanced or metastatic renal cell carcinoma than current therapy, according to results from a phase 3 clinical trial presented at the Presidential Symposium of the European Society for Medical Oncology's 2017 Congress in Spain.

13 Sep 2017

Study: New oral drug helps control glucose, reduces need for insulin in patients with type 1 diabetes

A University of Colorado Anschutz Medical Campus study finds sotagliflozin helps control glucose and reduces the need for insulin in patients with type 1 diabetes.

13 Sep 2017

Tulane University researchers develop new drug effective against malaria

Tulane University researchers have developed a new drug that is effective against non-severe cases of malaria, according to results from an FDA-supervised clinical trial published in the latest issue of The Lancet Infectious Diseases.

13 Sep 2017

Study finds potential preventive for chemotherapy-induced peripheral neuropathy

Chemotherapy-induced peripheral neuropathy, or CIPN, is a common side effect of cancer treatment that causes shooting or burning pain, numbness, tingling and cold sensitivity of the hands and feet for many cancer patients.

13 Sep 2017

VUMC and Bayer agree on strategic research alliance to develop new therapies for kidney diseases

Vanderbilt University Medical Center and Bayer have agreed on a five-year strategic research alliance to evaluate new drug candidates for the treatment of kidney diseases, with the goal of accelerating the translation of innovative approaches from the laboratory to pre-clinical development.

12 Sep 2017

People with severe emphysema may breathe better after EBV therapy, study shows

People with severe emphysema may breathe better after a minimally invasive procedure that places valves in the airways leading to diseased portions of their lungs, according to a randomized, controlled trial published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

12 Sep 2017

Combination therapy found to be effective adjuvant treatment option in melanoma patients

Combination targeted adjuvant therapy with dabrafenib and trametinib doubles relapse-free survival in patients with stage III BRAF-mutant melanoma, according to late-breaking results from the COMBI-AD trial presented today at the ESMO 2017 Congress in Madrid and published in the New England Journal of Medicine.

11 Sep 2017

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Pembrolizumab has shown a promising response rate in patients with pretreated metastatic gastric cancer, according to late-breaking results from the KEYNOTE-059 trial presented today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Combination treatment provides positive results for people with advanced melanoma

In a two-year UCLA-led study, nearly two-thirds of people with advanced melanoma responded positively to a treatment that combines the immunotherapy drug pembrolizumab with a herpes virus called talimogene laherpareovec, or T-VEC.

8 Sep 2017

Researchers define how cancer drug works in cells, mice and man

Science is very good at determining how drugs work in experimental models. New research out of Dartmouth's Norris Cotton Cancer Center led by Alan Eastman, PhD, helps to bridge the gap when it comes to ensuring that drugs work by the same mechanism in human patients.

7 Sep 2017

Predators in the scientific world plaguing research work finds major investigation

According to new research that looks at the research world itself, there is a huge percentage of journals that are publishing thousands of research papers of little value and poor quality. The results from this investigation were published yesterday, 7th September 2017 in the journal Nature in a study entitled, “Stop this waste of people, animals and money”.

6 Sep 2017

Reduced dose of chemotherapy has no effect on overall survival of liver cancer patients

Patients with the most common type of liver cancer who are taking the chemotherapy drug sorafenib can begin their treatment with a lower dose than is currently considered standard, and it will not affect how long they live when compared to patients who start on the full dose.

6 Sep 2017

Clinical Trial News and Research

FDA permits first digital therapeutic device for treatment of substance use disorders

FDA grants accelerated approval to new drug for treating relapsed follicular lymphoma

Patients diagnosed with glioblastoma benefit from care at high-volume centers, study suggests

New clinical trial begins testing Epigem’s instrument for detection, cure of rare anemias

Clinical trial evaluates key-hole and open surgery in pancreatic cancer patients

Michigan Medicine researchers receive $3.5m to combat fatigue in MS patients

Modified blood thinner may be first promising method to prevent repercussions after TBI

Researchers overcome major stumbling blocks in developing HIV vaccine

Combination immunotherapy shows better overall survival in kidney cancer patients

Study: New oral drug helps control glucose, reduces need for insulin in patients with type 1 diabetes

Tulane University researchers develop new drug effective against malaria

Study finds potential preventive for chemotherapy-induced peripheral neuropathy

VUMC and Bayer agree on strategic research alliance to develop new therapies for kidney diseases

People with severe emphysema may breathe better after EBV therapy, study shows

Combination therapy found to be effective adjuvant treatment option in melanoma patients

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Combination treatment provides positive results for people with advanced melanoma

Researchers define how cancer drug works in cells, mice and man

Predators in the scientific world plaguing research work finds major investigation

Reduced dose of chemotherapy has no effect on overall survival of liver cancer patients

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