Efficacy News and Research

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Dexamethasone use could reduce immune checkpoint inhibitor efficacy in glioblastoma patients

Bottom Line: Among patients with glioblastoma receiving an immune checkpoint inhibitor, those who received the corticosteroid dexamethasone at baseline for cerebral edema had significantly worse overall survival.

25 Nov 2020

Robust antibody response to SARS-CoV-2 can persist for eight months, study finds

A study conducted by researchers based in Italy suggests that SARS-CoV-2 induces durable and strong immunity in patients who had moderate to severe COVID-19.

25 Nov 2020

New drug lures stem cells to damaged tissue, improves treatment efficacy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a drug that can lure stem cells to damaged tissue and improve treatment efficacy--a scientific first and major advance for the field of regenerative medicine.

25 Nov 2020

Researchers assess the unique advantages of bacteria in cancer treatment

Announcing a new article publication for BIO Integration journal, the authors Meng Du; Jinsui Yu; Yaozhang Yang; Fei Yan and Zhiyi Chen from the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China and Shenzhen Institutes of Advanced Technology, Shenzhen, China, review the use of microbes in oncology.

24 Nov 2020

A review of Traditional Chinese herbal medicine in management of COVID-19

Now researcher have summarized the experiences with the use of traditional Chinese herbal medicines for the management of COVID-19. Their study titled, “Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis,” was published in the January 2021 issue of the journal Phytomedicine.

24 Nov 2020

Mefloquine shows potential as anti-SARS-CoV-2 drug

A team of scientists from Japan has identified the approved anti-material drug, mefloquine, as a potential candidate to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Specifically, mefloquine has been shown to prevent the entry of SARS-CoV-2 into host cells and reduce the viral load in vitro.

24 Nov 2020

Inexpensive molecule shows potential to fight antibiotic-resistant bacteria causing gonorrhea, meningitis

A team from the Institut national de la recherche scientifique (INRS) has demonstrated the effectiveness of an inexpensive molecule to fight antibiotic-resistant strains of the bacteria responsible for gonorrhea and meningococcal meningitis.

24 Nov 2020

Protection of upper respiratory tract will require vaccines that mimic natural infection by SARS-CoV-2

Recently, a team of researchers studied the transmission modes of SARS-CoV-2 and the protection against re-infection in ferret models in work published on the preprint server, bioRxiv.

24 Nov 2020

Study finds how the brain 're-wires' after neurological disease

Trinity College researchers are studying how the brain re-wires itself in neurological disease.

24 Nov 2020

Largest clinical trial launched to treat mild-to-moderate COVID-19 patients in Africa

Thirteen African countries and an international network of research institutions have joined forces to launch the largest COVID-19 clinical trial in mild-to-moderate outpatients in Africa.

24 Nov 2020

Potential treatment could reduce heart failure after a significant heart attack

While there are therapies to aid in overall heart health, there are very few preventative therapies for heart failure after a significant heart attack, a serious condition that has a very significant mortality.

24 Nov 2020

Sex steroids may play a protective role in COVID-19, shows study

A new paper from a UIC researcher shows evidence that suggests sex steroids may play a role in protecting against COVID-19 symptoms.

24 Nov 2020

Digital warm-start CRISPR assay enables sensitive quantitative detection of SARS-CoV-2 in clinical samples

In a recent medRxiv* preprint paper, researchers from the University of Connecticut Health Center in the United States unveil their digital warm-start CRISPR (WS-CRISPR) method for stringent and sensitive quantitative detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples of patients with coronavirus disease (COVID-19).

24 Nov 2020

Penn State researcher to study how vitamin D regulates host immunity to viral infection

Funding from the National Institutes of Health will enable a Penn State researcher to study whether vitamin D supplementation could help people ward off or reduce symptoms caused by COVID-19.

24 Nov 2020

Study: 58% of adults over 50 are willing to receive COVID-19 vaccination

Once enough people receive effective vaccines against the novel coronavirus, experts say, the end of the pandemic may be in sight. But a new poll of older adults - one of the highest-priority groups for vaccination - suggests an uphill climb lies ahead to reach that goal.

24 Nov 2020

Biosensor assay SARS-CoV-2 antibody test may predict COVID-19 severity in patients

Researchers in New York, USA, have found an association of mortality with an early humoral response to SARS-CoV-2 infection within the first few days after onset of symptoms (DAOS), using a highly sensitive and automated testing-on-a-probe (TOP) biosensor assays for SARS-CoV-2.

24 Nov 2020

Researchers conduct aerosol characterization experiments to protect healthcare workers from COVID-19

The rapid spread of COVID-19 overwhelmed hospitals that were unable to contend with the increasing number of patients, many requiring ventilators and other critical care. Such conditions can put medical workers at risk. Now researchers are studying methods to increase hospital safety and efficacy during the pandemic.

24 Nov 2020

Efficacy News and Research

Dexamethasone use could reduce immune checkpoint inhibitor efficacy in glioblastoma patients

Robust antibody response to SARS-CoV-2 can persist for eight months, study finds

New drug lures stem cells to damaged tissue, improves treatment efficacy

Researchers assess the unique advantages of bacteria in cancer treatment

A review of Traditional Chinese herbal medicine in management of COVID-19

Mefloquine shows potential as anti-SARS-CoV-2 drug

Inexpensive molecule shows potential to fight antibiotic-resistant bacteria causing gonorrhea, meningitis

Protection of upper respiratory tract will require vaccines that mimic natural infection by SARS-CoV-2

Study finds how the brain 're-wires' after neurological disease

Largest clinical trial launched to treat mild-to-moderate COVID-19 patients in Africa

Potential treatment could reduce heart failure after a significant heart attack

Sex steroids may play a protective role in COVID-19, shows study

Digital warm-start CRISPR assay enables sensitive quantitative detection of SARS-CoV-2 in clinical samples

Penn State researcher to study how vitamin D regulates host immunity to viral infection

Study: 58% of adults over 50 are willing to receive COVID-19 vaccination

Biosensor assay SARS-CoV-2 antibody test may predict COVID-19 severity in patients

Researchers conduct aerosol characterization experiments to protect healthcare workers from COVID-19

Early high-titer convalescent plasma prevents 75% of severe COVID-19 in elderly

New technology can provide immunization against infectious diseases

Marinomed to initiate clinical trial with Carragelose for preventing COVID19 in frontline healthcare staff

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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