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Common early sign of cardiovascular disease associated with cancer risk

A Mayo Clinic-led study involving 488 cardiac patients whose cases were followed for up to 12 years finds that microvascular endothelial dysfunction, a common early sign of cardiovascular disease, is associated with a greater than twofold risk of cancer.

31 Oct 2019

Novel method for aggressive breast cancer detection

A new study in rats published in the journal Cell Reports shows that the pattern of RNA molecules produced within certain immune cells called macrophages, found within breast cancers (tumor-associated macrophages, TAMs), can tell whether the tumor is cancerous or not and indicate the type of outcome. The same pattern is present in humans as in mice. This makes it directly useful in predicting the nature of a breast tumor and its outcome.

30 Oct 2019

Proton radiation therapy can help treat patients with hepatocellular carcinoma

Two new studies support and inform the use of proton radiation therapy to treat patients with hepatocellular carcinoma (HCC), a common but often fatal type of liver cancer for which there are limited treatment options. One study (Sanford et al.) suggests that proton radiation, compared to traditional photon radiation, can extend overall survival with reduced toxicity.

30 Oct 2019

New biomarker can track mitochondrial activity in lung tumors

Researchers at the UCLA Jonsson Comprehensive Cancer Center and David Geffen School of Medicine at UCLA have identified a new biomarker using a noninvasive imaging method that tracks mitochondrial activity in lung tumors.

30 Oct 2019

Kazan University showcases innovative antiseptic in Vienna

The event was co-organized by the Ministry of Industry and Trade of Russia, Skolkovo, Russian Venture Company, ChemRar, RDI Group, Vienna Business Agency, and others.

30 Oct 2019

Studies support use of proton radiation therapy to treat patients with fatal type of liver cancer

Two new studies support and inform the use of proton radiation therapy to treat patients with hepatocellular carcinoma, a common but often fatal type of liver cancer for which there are limited treatment options.

30 Oct 2019

Liquid biopsy can predict prognosis in patients with glioblastoma

A blood test that measures the amount of cell-free DNA (cfDNA) in the bloodstream - called a liquid biopsy - correlates with how patients will progress after they are diagnosed with glioblastoma (GBM), the deadliest and most common primary brain tumor in adults.

30 Oct 2019

Chemotherapy-induced senescent cells eat neighboring cells

A new study has found that chemotherapy-induced senescent cancer cells feed on other neighboring cells to enhance their survival.

30 Oct 2019

Novel, cost-effective method successfully identifies aggressive tumors

Researchers have developed a novel, cost-effective genomic method that can identify highly heterogenous tumors that are typically aggressive in nature.

30 Oct 2019

Atlantic Health System Cancer Care enrolling patients in five pancreatic cancer studies

November is National Pancreatic Cancer Awareness month. This year alone, more than 56,000 Americans will be diagnosed with pancreatic cancer. Pancreatic tumors are particularly aggressive and hard to treat "due to a mutational profile that makes it resistant to therapies that work better for other tumor types," explains Angela Alistar, MD, medical director of GI Oncology at Morristown Medical Center.

30 Oct 2019

Study: MIB2 improves inflammation by degrading CYLD enzyme

The tumor suppressor CYLD lysine 63 deubiquitinase (CYLD) is a deubiquitinating enzyme that suppresses polyubiquitin-dependent signaling pathways, including the proinflammatory and cell growth-promoting NF-κB pathway.

30 Oct 2019

Patient-specific dosimetry can improve treatment for neuroendocrine tumors

In neuroendocrine tumor treatment, different methods of predicting patient response may be required for different patients, according to new research published in the October issue of The Journal of Nuclear Medicine. By tailoring the method to the specific patient, physicians may better predict the effectiveness of treatment.

30 Oct 2019

Synthetic scaffolds could detect multiple types of cancers

Invasive procedures to biopsy tissue from cancer-tainted organs could be replaced by simply taking samples from a tiny "decoy" implanted just beneath the skin, University of Michigan researchers have demonstrated in mice.

29 Oct 2019

New method can indicate prognosis of aggressive breast cancer

Aggressive forms of breast cancer often manipulate the immune response in their favor. This manipulation is revealed in humans by the same immunological "signature" as in mice. This is shown by a study carried out by scientists from the University of Bonn together with Dutch colleagues.

29 Oct 2019

IDIBELL researchers identify involvement of cell membrane protein in liver cancer

Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have just described for the first time the crucial involvement of a cell membrane protein in the development and progression of liver cancer, according to an article published in the Journal of Hepatology.

29 Oct 2019

NUS researchers use glowing nanoparticles to control biological processes

The biological technique of 'optogenetics' uses light to control cells within living tissues that have been genetically modified to be light-sensitive.

29 Oct 2019

New research could help better understand progress of breast cancer

New research at Case Western Reserve University could help better determine which patients diagnosed with the pre-malignant breast cancer commonly as stage 0 are likely to progress to invasive breast cancer and therefore might benefit from additional therapy over and above surgery alone.

29 Oct 2019

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

NYU researcher awarded $1.7 million NIH grant to optimize cancer treatment

Weiqiang Chen, assistant professor of biomedical engineering and mechanical and aerospace engineering at the NYU Tandon School of Engineering, has been awarded the Maximizing Investigators' Research Award (R35) from the National Institute of General Medical Sciences, a division of the National Institutes of Health.

29 Oct 2019

Work in progress on medicine for treatment of ulcerative colitis

IKBFU center for clinical research scientists have participated in the international VARSITY clinical research. It's the world's first research aimed at finding the most effective drug among anti-inflammatory ones for the treatment of ulcerative colitis.

28 Oct 2019