Clinical Trial News and Research

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New app uses smartphone camera to provide detailed information about heart health

Want to know how healthy your heart is? Now there's an app for that. In a proof-of-concept clinical trial, engineers at Caltech, Huntington Medical Research Institute, and USC have demonstrated that the camera on your smartphone can noninvasively provide detailed information about your heart's health.

6 Sep 2017

Existing antidepressant drug could slow progression of Parkinson’s

Michigan State University scientists now have early proof that an antidepressant drug that's been around for more than 50 years could slow the progression of Parkinson's.

6 Sep 2017

Biodegradable nanoparticle injected after spinal cord injury limits damage

After a spinal cord injury, a significant amount of secondary nerve damage is caused by inflammation and internal scarring that inhibits the ability of the nervous system to repair itself.

5 Sep 2017

Mayo Clinic experts move closer to realizing clinical potential of senolytic drugs on aging

Researchers are moving closer to realizing the clinical potential of drugs that have previously been shown to support healthy aging in animals.

4 Sep 2017

Pfizer receives FDA approval for new therapy to treat adults and children with AML

Pfizer Inc. today announced that the U.S. Food and Drug Administration approved MYLOTARG (gemtuzumab ozogamicin) for adults with newly diagnosed CD33-positive acute myeloid leukemia (AML), and adults and children 2 years and older with relapsed or refractory CD33-positive AML.

1 Sep 2017

Researchers perform first-ever clinical trial involving genetic screening for Parkinson’s disease

In the first ever clinical investigation involving genetic screening for Parkinson's disease, researchers are testing whether the presence of a specific genetic mutation identifies which patients are the best candidates for deep brain stimulation surgery, and whether neurologists should perform that procedure differently based on that genetic information.

1 Sep 2017

St. Kitts launches probe of herpes vaccine tests on U.S. patients

The government of St. Kitts and Nevis has launched an investigation into the clinical trial for a herpes vaccine by an American company because it said its officials were not notified about the experiments.

31 Aug 2017

New trial examines whether compound given before and after bypass surgery mitigates cognitive deficits

University of Arizona researchers are collaborating on a Phase 2 trial to determine whether a particular peptide administered before and after coronary bypass surgery mitigates or even reverses cognitive deficits thought to be connected to the procedure.

31 Aug 2017

Study finds transcranial direct-current stimulation to be less effective than anti-depressants

A new study questions the efficacy of treatments for depression based on stimulating brain areas with low-intensity electric current. The technique, known as transcranial direct-current stimulation (tDCS), was considered a promising alternative to treatment with antidepressant drugs.

31 Aug 2017

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

The University of Chicago Medicine is one of a limited number of U.S. sites working to offer a breakthrough gene therapy for pediatric acute lymphoblastic leukemia (ALL), which was just approved by the U.S. Food and Drug Administration.

31 Aug 2017

St. Jude creates world’s largest collection of pediatric solid tumor samples

In an effort to improve outcomes for patients with some of the deadliest childhood cancers, St. Jude Children's Research Hospital scientists have created the world's largest collection of pediatric solid tumor samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.

31 Aug 2017

New drug shows promise to treat women with estrogen positive metastatic breast cancer

Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease.

31 Aug 2017

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

HHMI scientists expand access to new resource for studying pediatric cancers

Howard Hughes Medical Institute (HHMI) scientists have created an extensive resource for studying pediatric cancers, which they are sharing widely to help accelerate research.

30 Aug 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

FDA approves new antibacterial treatment for adults with cUTI

The U.S. Food and Drug Administration today approved Vabomere for adults with complicated urinary tract infections (cUTI), including a type of kidney infection, pyelonephritis, caused by specific bacteria. Vabomere is a drug containing meropenem, an antibacterial, and vaborbactam, which inhibits certain types of resistance mechanisms used by bacteria.

30 Aug 2017

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Scientists at Children's Hospital of Philadelphia report that a drug candidate that blocks abnormal protein signals may lead to the first pharmacologic treatment for hereditary multiple exostoses (HME), a rare pediatric genetic disease.

29 Aug 2017

Second Sight achieves milestone with conditional FDA approval to start Orion feasibility clinical trial

Second Sight Medical Products, Inc., a developer, manufacturer and marketer of implantable visual prosthetics to provide useful vision to blind patients, today announced that the Company has received conditional approval from the U.S. Food and Drug Administration to begin the Orion™ Cortical Visual Prosthesis System feasibility clinical study.

29 Aug 2017

Trial for PTSD treatment with MDMA-assisted psychotherapy receives FDA go-ahead

The United States Food and Drugs Administration FDA has granted permission for phase 3 trials in PTSD (Post traumatic stress disorder) patients using Ecstasy and psychotherapy in a treatment protocol called MDMA-Assisted Psychotherapy PTSD affects thousands of war veterans and other individuals and often leads to fatal outcomes of self-harm and suicides

28 Aug 2017

Clinical Trial News and Research

New app uses smartphone camera to provide detailed information about heart health

Existing antidepressant drug could slow progression of Parkinson’s

Biodegradable nanoparticle injected after spinal cord injury limits damage

Mayo Clinic experts move closer to realizing clinical potential of senolytic drugs on aging

Pfizer receives FDA approval for new therapy to treat adults and children with AML

Researchers perform first-ever clinical trial involving genetic screening for Parkinson’s disease

St. Kitts launches probe of herpes vaccine tests on U.S. patients

New trial examines whether compound given before and after bypass surgery mitigates cognitive deficits

Study finds transcranial direct-current stimulation to be less effective than anti-depressants

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

St. Jude creates world’s largest collection of pediatric solid tumor samples

New drug shows promise to treat women with estrogen positive metastatic breast cancer

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

HHMI scientists expand access to new resource for studying pediatric cancers

FDA approves first cell-based gene therapy for use in the United States

FDA approves new antibacterial treatment for adults with cUTI

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Second Sight achieves milestone with conditional FDA approval to start Orion feasibility clinical trial

Trial for PTSD treatment with MDMA-assisted psychotherapy receives FDA go-ahead

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