Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Prion infection of neurons increases the free cholesterol content in cell membranes

A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for cholesterol in other neurodegenerative diseases.

12 Feb 2008

Most hypertension patients ignore recommended diet

A relatively small proportion of individuals with hypertension (high blood pressure) eat diets that align with government guidelines for controlling the disease, according to a report in the February 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

12 Feb 2008

Hostility plus depression elevates risk for heart disease

Researchers led by Jesse Stewart, Ph.D., assistant professor of psychology at Indiana University-Purdue University Indianapolis, report that hostility and depression appear to act together in a complex way to elevate inflammatory proteins in the human body, possibly putting hostility plus depression on the list of risk factors for heart disease along with high blood pressure, elevated cholesterol, and smoking.

12 Feb 2008

Setting up a roadblock for atherosclerosis

Myriocin kills bacteria by disrupting the formation sphingomyelin, a fatty molecule that is a key part of their cell membranes.

8 Feb 2008

Scientists reveal a new target to fight bad cholesterol

Scientists have uncovered a new region in the genome that is responsible for the body's ability to regulate bad cholesterol which is linked to heart attack and stroke.

8 Feb 2008

Merck to pay over $650 million for fraudulent price reporting and kickbacks claims

Merck & Company has agreed to pay more than $650 million to resolve allegations that the pharmaceutical manufacturer failed to pay proper rebates to Medicaid and other government health care programs and paid illegal remuneration to health care providers to induce them to prescribe the company's products, the Justice Department has announced.

8 Feb 2008

Improving statins

Statin drugs are helping many people lower their cholesterol, but a new study in the February Journal of Lipid Research reveals that statins actually increase the production of another protein that limits their benefit.

8 Feb 2008

Faith-based health program expands, adds Latino classes

A nationally-recognized, faith-based physical activity and health promotion program that helps individuals adopt healthy lifestyles and manage chronic diseases is re-launching and extending its services to the African American and Latino communities in Monroe County.

8 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

7 Feb 2008

Chemical chaperone could open door to treatment of neurological disorder

An unexpected finding turned out to be a clue leading researchers at Washington University School of Medicine in St. Louis to propose a new treatment approach for Niemann-Pick disease, a rare, deadly neurodegenerative disorder.

7 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

5 Feb 2008

Researchers uncover key interaction in cholesterol regulation

Researchers at UT Southwestern Medical Center have determined the specific way in which a destructive protein binds to and interferes with a molecule that removes low-density lipoproteins (LDL), the so-called "bad" cholesterol, from the blood.

4 Feb 2008

Zinc may offer protection against cadmium exposure

Cadmium exposure is a known risk factor for prostate cancer, and a new University of Rochester study suggests that zinc may offer protection against cadmium.

4 Feb 2008

Low-intensity group support improves diet, may cut diabetes risk in American Indian women

Even low-intensity group support helps motivate young American Indian women to hit the produce aisle, a new study suggests.

30 Jan 2008

Evidence strongly supports diuretics as initial metabolic syndrome therapy, especially in black patients

New research shows that in people with high blood pressure as part of metabolic syndrome, a cluster of conditions that increases the risk for heart disease, diuretics offer greater protection against cardiovascular disease, including heart failure, and are at least as effective for lowering blood pressure as newer, more expensive medications.

28 Jan 2008

Researchers propose consumers buy yearly 'drug licenses' as new way to pay for prescriptions

Changing the way consumers pay for prescription drugs so that the system more closely resembles paying for cell phones or computer software could increase drug use without altering patients' out-of-pocket spending, health plan costs or drug company profits, according to a new RAND Corporation study.

23 Jan 2008

Researcher transplants stem cells to try to save patients' legs

A Northwestern University Feinberg School of Medicine researcher has launched the first U.S. trial in which a purified form of subjects' own adult stem cells was transplanted into their leg muscles with severely blocked arteries to try to grow new small blood vessels and restore circulation in their legs.

23 Jan 2008

Heart and stroke death rates steadily decline; risks still too high

In an appropriate prelude to American Heart Month, which is just ahead in February, new mortality data from the Centers for Disease Control and Prevention (CDC) shows that, since 1999, coronary heart disease and stroke age-adjusted death rates are down by 25.8 percent and 24.4 percent, respectively.

23 Jan 2008

Red meat and diet sodas - a recipe for metabolic syndrome

The latest research from the U.S. has found that people who eat two or more servings of red meat a day and drink diet sodas, are at risk of developing conditions leading to heart disease and diabetes.

23 Jan 2008

Fast-food consumption increases metabolic syndrome risk

Healthy adults who eat two or more servings of meat a day the equivalent of two burger patties increase their risk of developing metabolic syndrome by 25 percent compared with those who eat meat twice a week, according to research published in Circulation: Journal of the American Heart Association.

23 Jan 2008