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Detailed simulations reveal new information on sickle cell disease

Although there has yet to be a cure for sickle cell disease, researchers recently created detailed simulations on the Comet system at the San Diego Supercomputer Center (SDSC) showing how these stiff red blood cells flow through blood vessels, deforming and colliding along the way.

11 Dec 2020

COVID-19 infection may also affect the central nervous system, cause neurological disorders

COVID-19 is known primarily as a respiratory disease, with symptoms that include cough, shortness of breath, and, in severe cases, acute respiratory distress syndrome and pneumonia

10 Dec 2020

SARS-CoV-2 spike protein mediates acute lung pathology in mice

A study shows that the viral spike protein is adequate by itself to induce macrophage activation in pulmonary tissue and induce acute inflammation.

10 Dec 2020

Severe cortical damage associated with COVID-19 case report

In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began to cause a flu-like infection in people living in Wuhan, China.

10 Dec 2020

Beta-blockers show anti-inflammatory effects in cirrhosis

Approximately 170,000 people die every year in Europe from the direct consequences of advanced chronic liver disease (cirrhosis).

10 Dec 2020

Study shows how blood biomarkers and income can predict future disability

Blood tests for ‘biomarkers’ such as cholesterol and inflammation could predict whether you will be disabled in five years – according to research from the University of East Anglia.

10 Dec 2020

Colon lining releases hydrogen peroxide to protect the body from gut microbes

Scientists at UC Davis Health have discovered that an enzyme in the colon lining releases hydrogen peroxide (H2O2) - a known disinfecting compound- to protect the body from gut microbes.

9 Dec 2020

Study provides a detailed understanding of the interplay between obesity and cancer

Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival.

9 Dec 2020

Researchers identify new therapeutic target to treat patients with type 1 diabetes

Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes.

9 Dec 2020

Study links insulin resistance and ozone exposure to interstitial lung disease

People with pre-diabetes or diabetes who live in ozone-polluted areas may have an increased risk for an irreversible disease with a high mortality rate.

9 Dec 2020

RA patients in remission display higher temperatures than healthy individuals

A pioneering study carried out among patients in remission from Rheumatoid Arthritis has determined that they display significantly higher temperatures than healthy individuals.

9 Dec 2020

Neutrophils may play a key role in COVID-19-related thrombosis

A team of researchers in Italy have published a study suggesting that rather than platelets, neutrophils could be playing the lead role in thrombotic complications associated with COVID-19.

9 Dec 2020

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

A study conducted on mice published in the journal Geroscience has identified the action mechanism of a promising compound against Alzheimer's disease, developed by the team of Medical Chemistry and Pharmacology at the University of Barcelona.

9 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

Researchers find elevated biomarker for blood vessel damage in children with SARS-CoV-2

Researchers at Children's Hospital of Philadelphia have found elevated levels of a biomarker related to blood vessel damage in children with SARS-CoV-2 infection, even if the children had minimal or no symptoms of COVID-19.

8 Dec 2020

COVID-19 may be linked to acute appendicitis in children

Researchers at the University of Virginia have recently presented a case series pointing to a potential association between infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the development of acute appendicitis in children.

8 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020