Receptor News and Research

RSS

LJI researchers reveal unanticipated way by which neutrophils defend against invading pathogens

As an arm of the innate immune system, white blood cells called neutrophils form the first line of defense against invading pathogens.

31 Aug 2016

Scientists find new target that may lead to future treatments for Kennedy's disease

If a disease affects motoneurons, cells that control voluntary muscle activity, researchers should focus their efforts on motoneurons to find potential treatments, right? Not always.

31 Aug 2016

Study shows how caffeine counteracts age-related cognitive deficits in animals

A study published in the journal Scientific Reports from Nature publishing group, describes the mechanism by which caffeine counteracts age-related cognitive deficits in animals.

30 Aug 2016

Endogenous cannabinoid plays crucial role in activating spermatozoa for fertilization

During fertilization, a sperm must first fuse with the plasma membrane and then penetrate the female egg in order to penetrate it.

30 Aug 2016

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

In a study focusing on the role of self-donated (autologous) bone marrow-derived endothelial progenitor cells (EPCs) in placental vascular development, researchers in Japan have discovered that when transplanted into pregnant mice, EPCs can contribute to better blood vessel growth that helps in forming "normalized" placental vascularization, leading, in turn, to reduced recurrent miscarriages by providing a healthier fetal environment during gestation.

30 Aug 2016

Drug-eluting stents more beneficial to patients undergoing saphenous vein graft angioplasty

Drug-eluting stents had a clear advantage over bare metal stents in patients undergoing revascularisation of saphenous (leg) vein grafts, results of the BASKET-SAVAGE trial show.

30 Aug 2016

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Since the isolation of morphine from opium in the 19th century, scientists have hoped to find a potent opioid analgesic that isn't addictive and doesn't cause respiratory arrest with increased doses.

30 Aug 2016

Nicotinic receptors could be new therapeutic target to prevent memory loss linked to Alzheimer's

Several scientific studies have indicated that nicotine may be beneficial for memory function.

29 Aug 2016

NEJM publishes MINDACT trial results

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the peer-reviewed publication of the primary outcome results of the Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy (MINDACT) clinical trial in the prestigious New England Journal of Medicine (NEJM). (i, iii, iv) The publication demonstrates that 46% of breast cancer patients considered for chemotherapy, whose tumors are classified MammaPrint Low Risk, have excellent survival without chemotherapy, and can thus be candidates to avoid this toxic therapy.

29 Aug 2016

Novel inhibitory brain receptor reduces seizure-like activity in pubertal mice

More than half of children with epilepsy outgrow their seizures, yet the mechanism underlying this remission is unknown.

26 Aug 2016

Researchers show how cannabinoids affect vision

A multidisciplinary team including researchers from the Montreal Neurological Institute has improved our understanding of how cannabinoids, the active agent in marijuana, affect vision in vertebrates.

26 Aug 2016

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop treatment.

25 Aug 2016

People with high levels of four biomarkers may have increased risk for stroke

People with high levels of four biomarkers in the blood may be more likely to develop a stroke than people with low levels of the biomarkers, according to a study published in the August 24, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

25 Aug 2016

Researchers discover novel pathway for immune recovery following bone-marrow transplantation

New research has shown how a cell surface molecule, Lymphotoxin β receptor, controls entry of T-cells into the thymus; and as such presents an opportunity to understanding why cancer patients who undergo bone-marrow transplant are slow to recover their immune system.

25 Aug 2016

Avoiding foods high in AGEs could help protect from developing diabetes

Simple changes in how we cook could go a long way towards preventing diabetes, say researchers at the Icahn School of Medicine at Mount Sinai.

25 Aug 2016

AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice

Scientists have proposed that inflammation is the harbinger of aging and central to the aging process, a phenomenon described as 'inflamm-aging,' said Dr. Yuxiang Sun.

24 Aug 2016

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

Researchers at UT Southwestern Medical Center have identified a previously unknown role of a cellular signaling molecule involved in release of the "hunger hormone" ghrelin, a finding that could have implications for optimal treatment of children taking beta blockers.

23 Aug 2016

Receptor News and Research

LJI researchers reveal unanticipated way by which neutrophils defend against invading pathogens

Scientists find new target that may lead to future treatments for Kennedy's disease

Study shows how caffeine counteracts age-related cognitive deficits in animals

Endogenous cannabinoid plays crucial role in activating spermatozoa for fertilization

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

Drug-eluting stents more beneficial to patients undergoing saphenous vein graft angioplasty

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Nicotinic receptors could be new therapeutic target to prevent memory loss linked to Alzheimer's

NEJM publishes MINDACT trial results

Novel inhibitory brain receptor reduces seizure-like activity in pubertal mice

Researchers show how cannabinoids affect vision

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

People with high levels of four biomarkers may have increased risk for stroke

Researchers discover novel pathway for immune recovery following bone-marrow transplantation

Avoiding foods high in AGEs could help protect from developing diabetes

AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

Added benefit not proven for orphan drug in treatment of adults with stomach cancer

TSRI scientists find evidence supporting new therapeutic strategy against cocaine addiction

Common cold virus actually transmitted from camels to humans

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News