Efficacy News and Research

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Smell and taste changes in general population may indicate COVID-19 spread

Self-reports of smell and taste changes provide earlier markers of the spread of infection of SARS-CoV-2 than current governmental indicators, according to an international team of researchers.

11 Nov 2020

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

Low prevalence of SARS-CoV-2 specific antibodies in Lubbock, Texas

A recent study published in the Journal of Primary Care and Community Health has assessed the prevalence of antibodies developed specifically against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in front-line workers in Lubbock, Texas. According to the study findings, immunoglobulin G (IgG)-specific anti-SARS-CoV-2 antibodies have been detected in only 0.73% of the participants.

11 Nov 2020

Research tracks humoral immunity response over eight months post COVID-19 infection

Researchers from Chongqing Medical University have tried to answer one of the burning questions regarding the longevity of immune response to coronavirus disease 2019 (COVID-19): How long does immunity last after infection? Their study looked at the lasting effects and continued immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) over eight months after recovery from the infection.

11 Nov 2020

Experts publish Consensus Statement on management of osteoporosis in patients with CKD G4–G5D

Patients with advanced chronic kidney disease (CKD) suffer from impaired bone quality and quantity, with a non-vertebral fracture risk which is 4-to 6-fold higher than the fracture risk of matched controls.

11 Nov 2020

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective.

11 Nov 2020

Five important questions about Pfizer’s COVID-19 vaccine

Pfizer's announcement on Monday that its COVID-19 shot appears to keep nine in 10 people from getting the disease sent its stock price rocketing. Many news reports described the vaccine as if it were our deliverance from the pandemic, even though few details were released.

11 Nov 2020

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

The action of metformin, the classic drug used to treat diabetes by stabilizing blood sugar, can be blocked by a molecule from the bacteria in our intestines, a University of Gothenburg study shows.

11 Nov 2020

Ignis Health licenses Telehealth Service Implementation Model to set up new program

The Medical University of South Carolina and Ignis Health share a common goal - improving telehealth. Earlier this month, Ignis licensed the Telehealth Service Implementation Model (TSIM), a roadmap for setting up a telehealth program developed by Shawn Valenta, former administrator for the MUSC Health Center for Telehealth, and other telehealth experts at MUSC.

11 Nov 2020

Study focuses on efficacy of cognitive rehabilitation across a range of neurological conditions

A new text by Kessler Foundation scientists focuses on the efficacy of cognitive rehabilitation across a variety of neurological conditions, with specific emphasis on treatment-related changes in the brain detectable via neuroimaging.

11 Nov 2020

Preliminary analysis of xenograft versus organoids

The observance of Lung Cancer Awareness Month in November affords an opportunity to take stock of current approaches to lung cancer research, and to cancer research more widely.

11 Nov 2020

A promising vaccine for treating poorly immunogenic tumors

Patients with cancer have multiple treatment options available to them today, but each has its drawbacks. Chemotherapy kills rapidly dividing cancer cells, but it also damages healthy cells in the body and often does not effectively prevent tumor metastasis or disease recurrence.

11 Nov 2020

Loneliness levels highest in the 20s and lowest in the 60s, finds study

Loneliness is a prevalent and serious public health problem impacting health, well-being and longevity. Seeking to develop effective interventions, researchers at University of California San Diego School of Medicine examined the psychological and environmental factors that lead to patterns of loneliness in different age groups.

10 Nov 2020

Lessons from USS Theodore Roosevelt on limiting shipborne COVID-19 outbreaks

A new study published on the preprint server medRxiv* in November 2020 discusses such a scenario in terms of various possible approaches. It suggests that a viable strategy could be evacuating everyone from the ship and extensive surveillance testing.

10 Nov 2020

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

Over the next six years, research groups at Charité - Universitätsmedizin Berlin and Tel Aviv University will study how invasive fungal pathogens are able to evade treatments and develop tolerance to antifungal drugs.

10 Nov 2020

Identifying SARS-CoV-2 spike protein mutations resistant to antibodies

Using a set of different monoclonal antibodies, researchers determined different mutations in the SARS-CoV-2 spike protein that leads to resistance. Understanding these resistant mutations is important in developing effective therapeutic strategies.

10 Nov 2020

Flinders University receives funding for new brain cancer research project

The human brain’s biochemistry may be a stumbling block that has been preventing an effective cure for brain cancer.

10 Nov 2020

Novel 3D-printed scaffold loaded with chemotherapy drug could reduce breast cancer recurrence

The recurrence of cancer after surgery is a major concern for patients. New findings from a QUT study have shown the potential for a novel 3D-printed porous scaffold which is loaded with a common chemotherapy drug that can reduce breast cancer recurrence in an experimental setting.

10 Nov 2020

Mask wearing, social distancing considerably reduce incidence of many diseases

Measures to reduce the spread of COVID-19 through non-pharmaceutical interventions (NPIs) such as mask wearing and social distancing are a key tool in combatting the impact of the ongoing coronavirus pandemic.

10 Nov 2020

PhoreMost and Oxford Biomedica collaborate to develop next-generation CAR-T cell therapies

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to developing drugs against intractable disease targets, and Oxford Biomedica plc, a leading gene and cell therapy group, today announced that they have entered into a discovery collaboration to develop next-generation CAR-T cell therapies.

From PhoreMost 10 Nov 2020

Efficacy News and Research

Smell and taste changes in general population may indicate COVID-19 spread

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

Low prevalence of SARS-CoV-2 specific antibodies in Lubbock, Texas

Research tracks humoral immunity response over eight months post COVID-19 infection

Experts publish Consensus Statement on management of osteoporosis in patients with CKD G4–G5D

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

Five important questions about Pfizer’s COVID-19 vaccine

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

Ignis Health licenses Telehealth Service Implementation Model to set up new program

Study focuses on efficacy of cognitive rehabilitation across a range of neurological conditions

Preliminary analysis of xenograft versus organoids

A promising vaccine for treating poorly immunogenic tumors

Loneliness levels highest in the 20s and lowest in the 60s, finds study

Lessons from USS Theodore Roosevelt on limiting shipborne COVID-19 outbreaks

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

Identifying SARS-CoV-2 spike protein mutations resistant to antibodies

Flinders University receives funding for new brain cancer research project

Novel 3D-printed scaffold loaded with chemotherapy drug could reduce breast cancer recurrence

Mask wearing, social distancing considerably reduce incidence of many diseases

PhoreMost and Oxford Biomedica collaborate to develop next-generation CAR-T cell therapies

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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