Tumor News and Research

RSS

CRISPR helps find difficult to detect cancer cells

Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in the cancer cells that can make the cells invisible to the immune system normally. Some of the cancers cells can now develop other ways to disguise themselves from being killed by the immune system.

15 Oct 2019

Scientists develop more accurate method to find good targets for cancer immunotherapy

Ludwig Cancer Research scientists have developed a new and more accurate method to identify the molecular signs of cancer likely to be presented to helper T cells, which stimulate and orchestrate the immune response to tumors and infectious agents.

15 Oct 2019

New cancer treatment developed at Yale

Scientists at Yale have developed a method that assists the immune system in identifying and eliminating cancer cells that may be missed by other forms of immunotherapies.

15 Oct 2019

Ludwig scientists develop robust method to refine personalized cancer immunotherapy

14 Oct 2019

Dementia spreads via synaptic connections between brain networks

In a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia, adding to growing evidence that the loss of brain cells associated with dementia spreads via the synaptic connections between established brain networks.

14 Oct 2019

New system can help the immune system spot and eliminate tumors

Cancer cells are masters at avoiding detection, but a new system developed by Yale scientists can make them stand out from the crowd and help the immune system spot and eliminate tumors that other forms of immunotherapies might miss, the researchers report Oct. 14 in the journal Nature Immunology.

14 Oct 2019

New Penn Medicine study unravels the early makings of an exhausted T cell

The immune system struggles to defeat cancer or chronic infections because many of the T cells that leap into action end up "exhausted," rendering them ineffective against disease.

14 Oct 2019

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

In continuing efforts to find novel ways to kill cancer cells, researchers at the University of Maryland School of Medicine have identified a new pathway that leads to the destruction of cancer cells.

14 Oct 2019

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate (ADC) payloads, today announced data verifying the favorable toxicity profile and potent efficacy of its Pyridinobenzodiazepine (PDD) ADC payload platform in tumor cell models.

14 Oct 2019

SOX9 broadly modifies the severity of Alagille syndrome liver disease in mice

Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues.

11 Oct 2019

$RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers$

RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers

RESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can offer meaningful clinical benefit for patients with relapsed refractory metastatic malignancies.

11 Oct 2019

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

The authors have developed the Accelera TED platform to repurpose drugs for HNSCC treatment; using in vitro assays and in vivo models.

11 Oct 2019

Imaging tumor stiffness could aid delivery of treatment to most challenging cancers

Using a non-invasive imaging technique that measures the stiffness of tissues gives crucial new information about cancer architecture and could aid the delivery of treatment to the most challenging tumors, new research shows.

11 Oct 2019

Vaccine against gastrin may slow spread of pancreatic cancer

New research suggests a vaccine that blocks a digestive hormone may slow the spread of pancreatic cancer, potentially increasing survival rates. The study, published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology, was chosen as an APSselect article for October.

10 Oct 2019

Fetal gut has more well-developed immune capabilities than previously thought

Most biology textbooks explain that the fetal immune system is largely undeveloped and that it learns after being exposed to the world at birth. New research from the University of Pittsburgh School of Medicine and UPMC Children's Hospital of Pittsburgh challenges that paradigm, and provides the first comprehensive look at the immune system of the developing gut.

10 Oct 2019

TSC1 status may predict response to Hsp90 inhibitors in bladder cancer patients

The researchers have recently identified the tumor suppressor tuberous sclerosis complex 1 as a new co-chaperone of Hsp90 that affects Hsp90 binding to its inhibitors.

10 Oct 2019

Survey quantifies cancer patients' interest in pathology services

Some of the most important players on a cancer patient's health care team are people they typically never meet or interact with - the pathologists who evaluate their tissue samples to determine the type and stage of disease they have.

10 Oct 2019

New algorithm hand-picks which cancer mutations are promising targets for immunotherapy

As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack.

9 Oct 2019

More sensitive electrophysiology tools needed to study cancer cell populations

Bioelectricity of Cancer, a special issue of the peer-reviewed journal Bioelectricity, has just been published. Two promising discoveries are well delineated: an ultra-sensitive tool to detect cancer and a new therapeutic target for cancer immunotherapy.

9 Oct 2019

New blood test could help hasten the diagnosis of brain tumors

A blood test which could help to accelerate the diagnosis of brain cancer has been developed in research led at the University of Strathclyde.

9 Oct 2019

Tumor News and Research

CRISPR helps find difficult to detect cancer cells

Scientists develop more accurate method to find good targets for cancer immunotherapy

New cancer treatment developed at Yale

Ludwig scientists develop robust method to refine personalized cancer immunotherapy

Dementia spreads via synaptic connections between brain networks

New system can help the immune system spot and eliminate tumors

New Penn Medicine study unravels the early makings of an exhausted T cell

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

SOX9 broadly modifies the severity of Alagille syndrome liver disease in mice

RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

Imaging tumor stiffness could aid delivery of treatment to most challenging cancers

Vaccine against gastrin may slow spread of pancreatic cancer

Fetal gut has more well-developed immune capabilities than previously thought

TSC1 status may predict response to Hsp90 inhibitors in bladder cancer patients

Survey quantifies cancer patients' interest in pathology services

New algorithm hand-picks which cancer mutations are promising targets for immunotherapy

More sensitive electrophysiology tools needed to study cancer cell populations

New blood test could help hasten the diagnosis of brain tumors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News