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PSI-developed drug could increase survival chances for metastatic prostate cancer patients

Researchers at PSI have developed a new drug that could increase the survival chances of patients with metastatic prostate cancer.

4 Jul 2023

Growth factor study reveals potential breakthrough in obesity management

Study discusses the effects of a growth factor that showed promising results in mice in an obesity trial.

4 Jul 2023

Unlocking the link: COVID-19 restrictions tied to surge in invasive Group A Streptococcal infections

Researchers investigated the increased incidence of group A streptococci (GAS) infections.

4 Jul 2023

New regulatory system discovered in malaria parasite

Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood, and intrinsic parasite cues, via a factor called ApSigma, as identified by a recent study aided by Tokyo Tech's World Research Hub Initiative.

3 Jul 2023

New approach could improve accuracy of liquid biopsy tests

A research team led by Xianghong Jasmine Zhou, PhD, professor of Pathology and Laboratory Medicine at the David Geffen School of Medicine at UCLA, has made an important advancement to address one of the major challenges in cell-free DNA (cfDNA) testing, also known as liquid biopsy.

3 Jul 2023

Mutations in AGC kinase motif linked to colorectal cancer growth

Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling processes, and mutate key enzymes to promote tumor growth, resist therapies, and hasten its spread from the original site to the bloodstream or other organs.

3 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

Ancient retrovirus may be responsible for aggressive brain cancers

The median length of survival after diagnosis of glioblastoma is 14 months, but some of these brain tumors are more aggressive and resistant to treatment than others, and a new study from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests reactivation of an ancient retrovirus may be at least partly to blame.

3 Jul 2023

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

3 Jul 2023

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.

3 Jul 2023

Researchers discover a molecular switch that regulates lipid metabolism in cells

Our body's fat metabolism plays a vital role in energy production in our body. A research team at the University of Basel, Switzerland, has discovered a molecular switch that regulates lipid metabolism in our cells.

3 Jul 2023

Korean researchers develop hydrogel that could revolutionize treatment for female infertility

The Health Insurance Review & Assessment Service revealed that over the last year, more than 370,000 Koreans sought medical help for infertility or difficulties in conceiving.

3 Jul 2023

Research reveals how cells carry out the controlled release of mucins and insulin

Researchers from the Centre for Genomic Regulation (CRG) in Barcelona have published a study in the journal Nature Communications that reveals how cells carry out the controlled release of mucins and insulin, two crucial proteins for human health.

3 Jul 2023

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Induced pluripotent stem (iPS) cells have a great impact on biology and medicine, and they are expected to improve regenerative medicine.

3 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

SPG-15: A Mother's Fight for a Gene Therapy Cure, Maddi's Story

News Medical spoke to the CEO and founder of the Maddi Foundation to gain a patient perspective on how important research in gene therapy is.

3 Jul 2023

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Researchers used antibody testing to predict the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

3 Jul 2023

B Cell News and Research

PSI-developed drug could increase survival chances for metastatic prostate cancer patients

Growth factor study reveals potential breakthrough in obesity management

Unlocking the link: COVID-19 restrictions tied to surge in invasive Group A Streptococcal infections

New regulatory system discovered in malaria parasite

New approach could improve accuracy of liquid biopsy tests

Mutations in AGC kinase motif linked to colorectal cancer growth

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Ancient retrovirus may be responsible for aggressive brain cancers

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Researchers discover a molecular switch that regulates lipid metabolism in cells

Korean researchers develop hydrogel that could revolutionize treatment for female infertility

Research reveals how cells carry out the controlled release of mucins and insulin

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Base editing shows promise for treating sickle cell disease and beta thalassemia

SPG-15: A Mother's Fight for a Gene Therapy Cure, Maddi's Story

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Insights gained from genetically modified pig heart transplantation

Cutting-edge research: machine learning identifies early predictors of type 1 diabetes

New technology to capture and release cfDNA on nanowire surfaces from urine

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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