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Researchers identify antibodies that could protect against alphaviruses

Alphaviruses - mosquito-borne viruses that can trigger brain infections and arthritis - may have met their match.

19 Aug 2021

Phase I clinical study evaluates safety and pharmacokinetics of ExeVir's COVID-19 neutralizing antibody

ExeVir, which is developing single domain antibody therapies providing broad protection against viral infections, today announces that the first subjects have been dosed in a Phase I clinical study of XVR011, its llama-derived antibody for the treatment and prevention of COVID-19.

19 Aug 2021

Fruit fly provides insight into controlling carbs and fat

Incretins are hormones secreted by intestinal cells that regulate pancreatic insulin and glucagon to control sugar metabolism in mammals.

19 Aug 2021

Scientists identify a potent neutralizing nanobody against SARS-CoV-1

In a recently published article in the journal Virologica Sinica, scientists have described the development and validation of a potent nanobody that targets the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus (SARS-CoV). The nanobody efficiently and specifically blocks the interaction between RBD and angiotensin-converting enzyme 2 (ACE2) and neutralizes the virus.

19 Aug 2021

Study reveals ideal usage duration of medical face masks

In a paper published by the Journal of Hazardous Materials, researchers from Surrey's renowned Global Centre for Clean Air Research (GCARE) explore two key questions: how long a mask should be worn; and when should it be discarded, recycled or washed to optimize its usage time.

19 Aug 2021

Memory of specific events does not deteriorate with age in cuttlefish

Cuttlefish can remember what, where, and when specific events happened - right up to their last few days of life, researchers have found.

18 Aug 2021

Researchers create the first 3D-bioprinted model of active glioblastoma tumor

A scientific achievement for researchers at Tel Aviv University: printing an entire active and viable glioblastoma tumor using a 3D printer.

18 Aug 2021

The White House says boosters for all. Here’s what you need to know.

The Biden administration announced plans Wednesday to offer boosters to all U.S. adults as soon as next month, saying that recent data, including some made available only in the past few days, played a role in that decision.

18 Aug 2021

Study reveals how high dietary fructose increases rates of obesity and cancers

Eating fructose appears to alter cells in the digestive tract in a way that enables it to take in more nutrients, according to a preclinical study from investigators at Weill Cornell Medicine and NewYork-Presbyterian.

18 Aug 2021

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell.

18 Aug 2021

Rush to boosters sparks confusion, differing recommendations

When the Food and Drug Administration announced last week that a third dose of Moderna or Pfizer-BioNTech covid-19 vaccine may boost the immunity of some people who are immunocompromised, officials repeated their stance that fully vaccinated, healthy people do not need another dose.

18 Aug 2021

Scientists propose innovative method to test the effectiveness of coronavirus medicines

South Ural State University scientists have proposed an innovative method for testing the effectiveness of medicines for coronavirus. According to the researchers, it is necessary to focus on the maximum coincidence of the ligand and the receptor. The results of the work have been published in the highly-rated journal "Molecules"(Q1).

18 Aug 2021

ELRIG UK Announces Drug Discovery 2021 Event to Host SLAS’s Innovation AveNEW

The European Laboratory Research & Innovation Group today announced the programme details for Drug Discovery 2021.

From Society for Laboratory Automation and Screening (SLAS) 18 Aug 2021

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

A new study suggests a new coronavirus test developed by scientists from the University of Washington and the Brotman Baty Institute for Precision Medicine produces faster and more sensitive results than conventional PCR tests to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA.

18 Aug 2021

Specificity of serological assays against SARS-CoV-2 in patients with parasitic infections

A new study available on the pre-print server medRxiv* aims to assess the specificity of the serological assays of SARS-CoV-2 antibodies among patients known to have a tissue-borne parasitic infection or those who reside in areas where the virus is endemic.

18 Aug 2021

SpeeDx expands product line of research reagents for SARS-CoV-2 variant analysis

SpeeDx Pty. Ltd., a developer of innovative molecular diagnostic solutions, have expanded their product line of research reagents for COVID-19 variant analysis to include a mutation connected to the SARS-CoV-2 Delta variant of concern.

18 Aug 2021

New bioengineered lung model could help scientists to advance research in lung conditions

An interdisciplinary team of researchers from McMaster and SickKids are developing a cutting-edge lung model that can better respond to viruses and drug treatments, giving scientists a tool to advance research in lung conditions like COVID-19, cystic fibrosis and allergens for asthma and air pollution.

18 Aug 2021

Age and sex affect the outcomes of time-restricted eating

Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles.

17 Aug 2021

Delta variant unable to evade antibodies elicited by COVID-19 vaccination, finds study

Despite causing a surge in infections this summer that has resulted in thousands of hospitalizations and deaths, the delta variant of the virus that causes COVID-19 is not particularly good at evading the antibodies generated by vaccination, according to a study by researchers at Washington University School of Medicine in St. Louis.

17 Aug 2021

Using self-assembled drugs to achieve a breakthrough in cancer therapy

One of the most challenging aspects of cancer treatment is the huge variety of different tumors that can occur with each one potentially requiring a different solution because unfortunately, one drug does not fit all.

17 Aug 2021