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Unique immune cell linked to remission in patients with triple negative breast cancer

A unique type of immune cell has been discovered in human breast tissue, and breast cancer patients with more of these cells are more likely to survive, finds new research from the Francis Crick Institute and King's College London.

From The Francis Crick Institute 9 Oct 2019

Study evaluates role of PET/CT in selecting candidates for peptide receptor radionuclide therapy

A new study published in The Journal of Nuclear Medicine evaluated the role of 68Ga-DOTATATE positron emission tomography/computed tomography in selecting neuroendocrine tumor patients who may benefit from peptide receptor radionuclide therapy.

9 Oct 2019

Combination treatment cures pancreatic cancer, reprograms the immune system

A University of Rochester Wilmot Cancer Institute research team reports that combining a type of radiation therapy with immunotherapy not only cures pancreatic cancer in mice, but appears to reprogram the immune system to create an "immune memory" in the same way that a vaccine keeps the flu away.

8 Oct 2019

Biology and computers meld to help understand how breast cancer develops

Among the most deadly killers in the area of cancer, breast cancer is also extremely difficult to treat, once it has spread to the bones. Not only does it metastasize rapidly, but it comprises a variety of cell types and also depends on the input from many other non-breast cells during the initiation, growth and spread of the cancer. This complexity makes it more difficult to develop targeted therapies in this condition.

8 Oct 2019

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

Patients with advanced melanoma have been able to live longer because of several newly approved targeted treatment options, including BRAF and MEK inhibitors. However, patients will often have different responses to the same treatment due to genetic variability.

8 Oct 2019

New understanding of breast cancer metastasis to bone

In breast cancer patients with metastatic disease, bone is the most common site of metastasis and the most common site of first distant relapse, with roughly half (48%) of breast cancer patients developing bone metastases after treatment.

8 Oct 2019

New grants support research on mechanics of tumor cells

At the cellular level, cancer can be viewed as a mechanical engineering challenge. The disease alters the structure and function of cells and tissues, which are meant to perform very specific tasks.

8 Oct 2019

Study receives NCI grant to explore better treatment for brain tumors in children

Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these tumors use to protect themselves from the child's natural immune response.

8 Oct 2019

Collagen fiber length may be a key overlooked parameter used by normal cells to become invasive

Collagen is the most abundant protein in mammals, making up skin, bone, tendons and other soft tissues. Its fibrous nature helps cells to move throughout the body, but until now, it wasn't clear how the length of fibers influences how cells move in groups.

8 Oct 2019

Salford scientists identify new drug candidate to starve and suffocate breast cancer stem cells

Scientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for new therapies to treat breast cancer patients.

8 Oct 2019

Patients' blood samples and biopsies reveal secrets of lung cancer spread

Early signs that a patient’s lung cancer may spread and become untreatable can be picked up in samples of their blood and tumor, according to a trio of papers published in Nature Medicine today (Monday).

8 Oct 2019

New insight into meningioma - possibility of targeted therapy

A new study published in the journal Oncotarget shows that certain mutations in the brain tumor called meningioma may help identify patients who have a better chance of recovery. This could help physicians make better clinical decisions based on more accurate diagnoses. It has also unveiled some of the genes that go wrong in meningiomas, as well as showing how targeted therapy could one day help fight this tumor.

7 Oct 2019

Researchers identify proteins critical for spreading of breast cancer to bones

Once breast cancer spreads to bone, treatment becomes nearly impossible. Breast cancer cells can lie dormant in the bone, often undetectable and able to escape typical treatments.

7 Oct 2019

Study identifies genetic marker which could personalize treatment for Crohn's disease

The largest study ever to look at why an expensive and commonly used group of drugs fails some patients with Crohn's disease has identified a genetic marker which could individualize drug treatment.

7 Oct 2019

Study highlights practice patterns and factors associated with prognosis of male breast cancer

A recent analysis reveals that treatment of male breast cancer has evolved over the years. In addition, certain patient-, tumor-, and treatment-related factors are linked with better survival. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

7 Oct 2019

Common genetic variant explains why immunotherapy often fails in Crohn's disease

The reason why a commonly used range of immunotherapy drugs is not effective in some patients with Crohn’s disease has so far not been identified, until now.

7 Oct 2019

Stratasys' new Digital Anatomy 3D Printer helps create a realistic training environment

3D printing leader Stratasys Ltd. is further extending its commitment to the medical industry with the new J750™ Digital Anatomy™ 3D Printer. Designed to replicate the feel, responsiveness, and biomechanics of human anatomy in medical models – the system improves surgical preparedness and training while helping bring new medical devices to market faster.

From Stratasys 7 Oct 2019

Understanding treatment and prognosis of male breast cancer

October is Breast Cancer Awareness Month, an annual campaign to raise awareness about the potentially-fatal disease. Breast cancer is known as an illness that affects mostly women, but about 1 percent of all breast cancers affect men, too.

7 Oct 2019

Novel drug may be the answer in battling resistance in aggressive breast cancer

Breast cancer is one of the most frequently diagnosed cancers in women across the globe. It represents one in four of all cancers in women. The survival rates for breast cancer vary across the globe, but when it comes to the metastatic or advanced breast cancer type, it is currently incurable, but there are many treatments available.

7 Oct 2019

Research provides new insights into tumorigenesis of meningioma

The identification of oncogenic mutations has provided further insights into the tumorigenesis of meningioma and the possibility of targeted therapy.

5 Oct 2019

Tumor News and Research

Unique immune cell linked to remission in patients with triple negative breast cancer

Study evaluates role of PET/CT in selecting candidates for peptide receptor radionuclide therapy

Combination treatment cures pancreatic cancer, reprograms the immune system

Biology and computers meld to help understand how breast cancer develops

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

New understanding of breast cancer metastasis to bone

New grants support research on mechanics of tumor cells

Study receives NCI grant to explore better treatment for brain tumors in children

Collagen fiber length may be a key overlooked parameter used by normal cells to become invasive

Salford scientists identify new drug candidate to starve and suffocate breast cancer stem cells

Patients' blood samples and biopsies reveal secrets of lung cancer spread

New insight into meningioma - possibility of targeted therapy

Researchers identify proteins critical for spreading of breast cancer to bones

Study identifies genetic marker which could personalize treatment for Crohn's disease

Study highlights practice patterns and factors associated with prognosis of male breast cancer

Common genetic variant explains why immunotherapy often fails in Crohn's disease

Stratasys' new Digital Anatomy 3D Printer helps create a realistic training environment

Understanding treatment and prognosis of male breast cancer

Novel drug may be the answer in battling resistance in aggressive breast cancer

Research provides new insights into tumorigenesis of meningioma

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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