Cell Cycle News and Research

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Chemical disruption to key interaction shown to limit metastasis in test mice

Finding ways to counteract or disrupt the invasive nature of cancer cells, called "metastasis," has been a long-term goal of cancer researchers. Now, researchers at Moffitt Cancer Center in Tampa, Fla., have identified an interactive pathway that regulates metastases in some cancers that may be vulnerable to chemical targeting in order to prevent cancer cell proliferation and tumor growth.

14 Dec 2011

NYUCI experts present latest research findings about hematologic cancers at 53rd ASH meeting

Experts from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, presented their latest research findings about hematologic cancers at the 53rd ASH Annual Meeting and Exposition held December 10-13, 2011 in San Diego, California.

14 Dec 2011

Researchers identify interactive pathway that regulates cancer metastasis

14 Dec 2011

DNA sequencing identifies new altered genes that drive CLL

The most comprehensive search to date of DNA abnormalities in chronic lymphocytic leukemia (CLL) has unearthed several new altered genes that drive this common blood cancer, a finding that could potentially help doctors predict whether an individual patient's disease will progress rapidly or remain indolent for years, say scientists from Dana-Farber Cancer Institute and the Broad Institute.

13 Dec 2011

Researchers reveal contribution of telomerase in controlling genetic code integrity

Researchers have revealed how a molecule called telomerase contributes to the control of the integrity of our genetic code, and when it is involved in the deregulation of the code, its important role in the development of cancer.

9 Dec 2011

Researchers reveal how podocytes may regenerate themselves during normal kidney function

Damage to podocytes -- a specialized type of epithelial cell in the kidney -- occurs in more than 90 percent of all chronic kidney disease. Now researchers at the Stanford University School of Medicine have uncovered an unexpected pathway that reveals for the first time how these cells may regenerate and renew themselves during normal kidney function.

6 Dec 2011

Blocking telomerase increases cancer cells' sensitivity to radiation treatment

Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells' sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research.

2 Dec 2011

Researchers identify cancer cell mitochondria as 'Achilles' heel' of tumor growth

Researchers at the Kimmel Cancer Center at Jefferson have identified cancer cell mitochondria as the unsuspecting powerhouse and "Achilles' heel" of tumor growth, opening up the door for new therapeutic targets in breast cancer and other tumor types.

2 Dec 2011

Study presents high-resolution genome-wide p53-binding map for normal human cells

Scientists investigating the interactions, or binding patterns, of a major tumor-suppressor protein known as p53 with the entire genome in normal human cells have turned up key differences from those observed in cancer cells. The distinct binding patterns reflect differences in the chromatin (the way DNA is packed with proteins), which may be important for understanding the function of the tumor suppressor protein in cancer cells.

1 Dec 2011

Researchers identify new cancer drug discovery approach

Researchers at the University of California, San Diego School of Medicine and the UC San Diego Moores Cancer Center have identified a new drug discovery approach enabling the destruction of the most highly proliferative tumors.

14 Nov 2011

Study: Children with autism have more prefrontal brain neurons

In a small, preliminary study that included 13 male children, those with autism had an average 67 percent more prefrontal brain neurons and larger than average brain weight, than children without autism, according to a study in the Nov. 9 issue of JAMA.

9 Nov 2011

PKM2 enzyme has important non-metabolic functions in cancer formation

The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers. Now, a team led by researchers at the University of Texas MD Anderson Cancer Center reports in advance online publication of the journal Nature that PKM2 has important non-metabolic functions in cancer formation.

7 Nov 2011

Researchers shed light on inner workings of endocycle

An international team of researchers led by investigators in the U.S. and Germany has shed light on the inner workings of the endocycle, a common cell cycle that fuels growth in plants, animals and some human tissues and is responsible for generating up to half of the Earth's biomass.

31 Oct 2011

Researchers identify cancer cell cycle-regulated mechanism

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells.

22 Oct 2011

Scientists discover complex cell mechanism that becomes an obstacle for radiation effectiveness

Researchers from Massachusetts General Hospital, Harvard Medical School and CIC bioGUNE discover a complex cell mechanism activated by a protein —HOXB9— that becomes an obstacle for radiation effectiveness.

20 Oct 2011

AICR recommends intake of cancer-fighting foods

Colleen Spees has always been interested in the role that diet played in disease, and set her sights on a career where she would counsel patients and train future dietitians. With multiple family members diagnosed with various types of cancer, Colleen decided to make the transition from clinical professional and nutrition educator to research scientist.

18 Oct 2011

Study identifies three new chromosomal regions implicated in susceptibility to melanoma

The genomic analysis technologies enable the study of genetic factors related to numerous diseases. In few areas this researches brought such a big and useful volume of information as in the case of melanoma.

10 Oct 2011

Kimmel Cancer Center at Jefferson celebrates two decades of caring and collaboration to beat cancer

From October forward, the Kimmel Cancer Center at Jefferson (KCC), a National Cancer Institute-designated cancer center, is celebrating 20 years of service to the community and the groundbreaking cancer research from the scientists and physicians who've provided an invaluable contribution to medical science and healthcare.

30 Sep 2011

Scientists discover effective target to kill late-stage metastatic prostate cancer cells

Purdue University scientists believe they have found an effective target for killing late-stage, metastatic prostate cancer cells.

29 Sep 2011

Study reveals possible new treatment targets for diffuse intrinsic pontine gliomas

Study led by St. Jude Children's Research Hospital scientists points to possible new treatment targets for diffuse intrinsic pontine gliomas; may tip the scales in the current debate about tumor biopsies.

21 Sep 2011

Cell Cycle News and Research

Chemical disruption to key interaction shown to limit metastasis in test mice

NYUCI experts present latest research findings about hematologic cancers at 53rd ASH meeting

Researchers identify interactive pathway that regulates cancer metastasis

DNA sequencing identifies new altered genes that drive CLL

Researchers reveal contribution of telomerase in controlling genetic code integrity

Researchers reveal how podocytes may regenerate themselves during normal kidney function

Blocking telomerase increases cancer cells' sensitivity to radiation treatment

Researchers identify cancer cell mitochondria as 'Achilles' heel' of tumor growth

Study presents high-resolution genome-wide p53-binding map for normal human cells

Researchers identify new cancer drug discovery approach

Study: Children with autism have more prefrontal brain neurons

PKM2 enzyme has important non-metabolic functions in cancer formation

Researchers shed light on inner workings of endocycle

Researchers identify cancer cell cycle-regulated mechanism

Scientists discover complex cell mechanism that becomes an obstacle for radiation effectiveness

AICR recommends intake of cancer-fighting foods

Study identifies three new chromosomal regions implicated in susceptibility to melanoma

Kimmel Cancer Center at Jefferson celebrates two decades of caring and collaboration to beat cancer

Scientists discover effective target to kill late-stage metastatic prostate cancer cells

Study reveals possible new treatment targets for diffuse intrinsic pontine gliomas

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry focus eBook - The Digital Laboratory (4th edition)

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (3rd Edition)

BFEB: Advances in microplate-based assays and analysis

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation