Clinical Trial News and Research

RSS

Single-dose oral cholera vaccine shows promising results in early clinical trial

Clinical trial shows promising results for PanChol, a single-dose oral vaccine aimed at the up to 4 million annual cholera cases worldwide.

7 Jan 2026

Web-app helps children with epilepsy to fall asleep earlier

An evidence-based web-app helped children with epilepsy to fall asleep on average 16.5 minutes earlier.

7 Jan 2026

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

Enveda, a multi-asset clinical-stage biotech company pioneering the discovery and development of a new generation of small-molecule drugs derived from life’s chemistry, has announced that the US Food and Drug Administration (FDA) has cleared the Company’s Investigational New Drug (IND) application for ENV-6946.

From Hanson Wade Group - 4th Precision Medicine in Inflammatory Bowel Disease Summit 6 Jan 2026

The gut is not just digestive and new evidence shows it actively controls brain function

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

6 Jan 2026

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

6 Jan 2026

TAAR1 mutation impairs brain signaling in schizophrenia

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.

6 Jan 2026

Finger-prick blood tests enable remote detection of Alzheimer’s biomarkers

A groundbreaking international study has demonstrated that Alzheimer's disease biomarkers can be accurately detected using simple finger-prick blood samples that can be collected at home and mailed to laboratories without refrigeration or prior processing.

5 Jan 2026

New trial aims to improve both survival and quality of life for men with advanced prostate cancer

The Alliance for Clinical Trials in Oncology has launched a randomized phase III clinical trial called RECIPROCAL (Alliance A032304) to explore whether doctors can optimize the timing of targeted radiation therapy to minimize side effects while preserving efficacy in men with advanced prostate cancer.

5 Jan 2026

Progesterone mimic plus anti-estrogen treatment slows tumor growth in breast cancer patients

A drug mimicking the hormone progesterone has anti-cancer activity when used together with conventional anti-estrogen treatment for women with breast cancer, a new Cambridge-led trial has found.

5 Jan 2026

Elevated bacteria levels in tumors weaken immune response, studies show

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

2 Jan 2026

Simple reminder emails increase clinicians' use of database for safe opioid prescribing

A new randomized clinical trial finds that simple reminder emails substantially increase clinicians' use of a database that supports safe prescribing of opioids and other drugs, even though opioid prescribing patterns themselves did not meaningfully change during the study period.

30 Dec 2025

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Diabetic kidney disease affects a growing proportion of people with diabetes and remains the leading cause of end-stage renal disease.

30 Dec 2025

Combination therapy offers hope for AML patients facing drug resistance

A research team at Oregon Health & Science University has discovered a promising new drug combination that may help people with acute myeloid leukemia overcome resistance to one of the most common frontline therapies.

30 Dec 2025

Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast cancer.

26 Dec 2025

Restoring brain energy balance reverses Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

23 Dec 2025

Digital patient records improve survival in HIV treatment clinics

With 9.5% of its population estimated to be HIV-positive in 2019, Malawi has one of the highest rates of HIV prevalence in the world.

22 Dec 2025

Women may derive greater long-term benefits from coronary artery bypass grafting compared with stents

Women with severe coronary heart disease causing narrowing or blockages in the arteries may derive greater long-term benefits from coronary artery bypass grafting compared with percutaneous coronary intervention, also known as stenting, according to a large study by Weill Cornell Medicine investigators.

22 Dec 2025

Long-approved drug shows promise in slowing neuron loss in Alzheimer’s disease

Scientists at the University of Colorado Anschutz have discovered that while brain neuron changes, including cell loss, may begin in early life, a drug long-approved for other conditions might be repurposed to slow this damage, offering new hope for those with Alzheimer's disease (AD) and other cognition issues.

19 Dec 2025

Cutting carbs, not fat, may better control appetite in women

Research indicates low-carb diets may enhance appetite regulation and reduce food cues in women with lipedema, offering a dietary intervention advantage.

19 Dec 2025

Financial barriers drive low participation in cancer clinical trials

A study by Case Western Reserve University and University Hospitals researchers has overturned long-held assumptions about why more cancer patients don't enroll in clinical trials that could potentially save their lives.

18 Dec 2025

Previous
1
...
43
44
45
46
47
48
49
...
1192
Next

Clinical Trial News and Research

Single-dose oral cholera vaccine shows promising results in early clinical trial

Web-app helps children with epilepsy to fall asleep earlier

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

The gut is not just digestive and new evidence shows it actively controls brain function

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

TAAR1 mutation impairs brain signaling in schizophrenia

Finger-prick blood tests enable remote detection of Alzheimer’s biomarkers

New trial aims to improve both survival and quality of life for men with advanced prostate cancer

Progesterone mimic plus anti-estrogen treatment slows tumor growth in breast cancer patients

Elevated bacteria levels in tumors weaken immune response, studies show

Simple reminder emails increase clinicians' use of database for safe opioid prescribing

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Combination therapy offers hope for AML patients facing drug resistance

Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

Restoring brain energy balance reverses Alzheimer’s disease in mouse models

Digital patient records improve survival in HIV treatment clinics

Women may derive greater long-term benefits from coronary artery bypass grafting compared with stents

Long-approved drug shows promise in slowing neuron loss in Alzheimer’s disease

Cutting carbs, not fat, may better control appetite in women

Financial barriers drive low participation in cancer clinical trials

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology