Interferon News and Research

RSS

Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer.

5 Apr 2022

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Researchers profiled cardiac tissue transcriptomes of COVID-19 patients.

5 Apr 2022

Prior COVID vaccination induces a more robust antibody response to Omicron

A recent study posted to the medRxiv* preprint server assessed the impact of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination on the human immune response against SARS-CoV-2 Omicron infection.

5 Apr 2022

Value of information analysis on clinical trial data to help approve or reject new COVID-19 drugs

Researchers quantified the cost-effective health benefits of pursuing further research or approving or rejecting COVID-19 drugs based on the existing research using a novel method called VOI analysis.

4 Apr 2022

TLR7 and MARK1 genomic variants impact COVID-19 prognosis

Researchers conduct a massive exome-wide genome study to explore the connections between gene variants/deleterious mutations and COVID-19 outcomes.

3 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Researchers examined the unique clusters of monocytes and regulatory T cells in the circulating blood from convalescent COVID-19 patients over a prolonged period after recovery, using scRNA sequencing.

31 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

Antiviral functions of interferon regulatory factors during human coronavirus infection

Researchers assessed the roles of the interferon regulatory factors: IRF1, IRF3, and IRF7 in infections by human coronaviruses.

30 Mar 2022

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A new study reported systemic and mucosal immunity against SARS-CoV-2 via intranasal delivery of a vaccine containing recombinant SARS-CoV-2 antigens, nucleocapsid, and spike subunit.

30 Mar 2022

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes respiratory coronavirus disease 2019 (COVID-19) triggered an unprecedented public health emergency. Human mobility patterns were fundamental to the spread of SARS-CoV-2 globally. The situation is particularly acute in a country like Saudi Arabia, which has seen more than 750,000 cases and over 9,000 deaths as of March 30th, 2022.

29 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

Interferon News and Research

Phenotypic changes in monocytes from COVID-19 patients

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Prior COVID vaccination induces a more robust antibody response to Omicron

Value of information analysis on clinical trial data to help approve or reject new COVID-19 drugs

TLR7 and MARK1 genomic variants impact COVID-19 prognosis

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Role of SARS-CoV-2 S1 subunit in severe COVID-19

Antiviral functions of interferon regulatory factors during human coronavirus infection

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

The different actions of CBD in SARS-CoV-2 infection

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

Examining differences in neurological manifestations induced by SARS-CoV-2 variants in hamsters

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

Tuberculosis infection protects mice against COVID-19

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News