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Synthetic solutions for ethical and effective drug testing

Improving human quality of life with drug treatments is a complicated issue. Drug certification, including drug safety and reliability, entails a long series of tests and government approvals before the drug is available for anyone to use.

22 Jul 2024

Study reveals a promising approach to developing universal influenza vaccine

New research led by Oregon Health & Science University reveals a promising approach to developing a universal influenza vaccine - a so-called "one and done" vaccine that confers lifetime immunity against an evolving virus.

19 Jul 2024

Porcine study reveals meurotoxic and pro-inflammatory effects of microplastics on enteric nervous system

Researchers investigates the effects of polyethylene terephthalate microplastics on the neuronal population in the porcine jejunum.

18 Jul 2024

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Researchers compared the distribution of sialic acid receptors in the respiratory tract and mammary glands of dairy cattle naturally infected with the highly pathogenic avian influenza A(H5N1) virus.

18 Jul 2024

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.

15 Jul 2024

Burning ammonia for maritime fuel could lead to devastating public health impacts

As container ships the size of city blocks cross the oceans to deliver cargo, their huge diesel engines emit large quantities of air pollutants that drive climate change and have human health impacts.

11 Jul 2024

Prime editing offers promising path to permanent treatment for cystic fibrosis

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection.

11 Jul 2024

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network.

10 Jul 2024

AI model can estimate lung function from chest radiographs with high accuracy

If there is one medical exam that everyone in the world has taken, it's a chest x-ray. Clinicians can use radiographs to tell if someone has tuberculosis, lung cancer, or other diseases, but they can't use them to tell if the lungs are functioning well.

8 Jul 2024

Plant-derived substance shows promise against pulmonary hypertension

A substance derived from the plant Ardisia crenata works in a different way than existing drugs. And in doing so, it is highly effective.

8 Jul 2024

Repurposing cancer drug to prevent organ damage in infectious diseases

Twelve years ago, cancer researchers at University of California San Diego identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue.

3 Jul 2024

Low-dose aspirin shows promise in treating flu-related vascular inflammation during pregnancy

A world-first study has found low-dose aspirin may treat flu-induced blood vessel inflammation, creating better blood flow to the placenta during pregnancy.

2 Jul 2024

Study reveals new mechanisms behind severe COVID-19 in obese individuals without diabetes

Already at the beginning of the COVID-19 pandemic, a group of Brazilian researchers pioneered in showing why SARS-CoV-2 infection tends to be more severe in diabetic patients.

2 Jul 2024

Reducing air pollution exposure could help prolong independent living for older adults, study suggests

Long-term exposure to air pollution can lead to a loss of independence for older adults, according to a University of Michigan study.

1 Jul 2024

How lifestyle and air pollution patterns affect mortality

Study found that both unhealthy lifestyle choices and higher air pollution levels significantly increase the risk of all-cause mortality, emphasizing the need for coordinated health and environmental interventions.

30 Jun 2024

Microscopic changes in the liver can be used to predict pancreatic cancer spread

Microscopic changes in the liver can be used to predict if, and where, pancreatic cancer may spread in the body.

28 Jun 2024

AI models may be using “demographic shortcuts” when making medical diagnostic evaluations

Artificial intelligence models often play a role in medical diagnoses, especially when it comes to analyzing images such as X-rays. However, studies have found that these models don't always perform well across all demographic groups, usually faring worse on women and people of color.

28 Jun 2024

Precise intensity-modulated radiotherapy outperforms 3D-CRT in advanced lung cancer

Results from a new study led by researchers at The University of Texas MD Anderson Cancer Center support standard use of the more precise intensity-modulated radiotherapy (IMRT) over the alternative 3D-conformal radiotherapy (3D-CRT) for patients with unresectable, locally advanced non-small cell lung cancer (NSCLC).

27 Jun 2024

Researchers develop a more accurate way to scan for tuberculosis using PET

A more accurate way to scan for tuberculosis (TB) has been developed by UK and US researchers, using positron emission tomography (PET).