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New method helps to analyze proteins during dynamic processes on biological membranes

A large proportion of biologically relevant processes take place at membranes. Studying the dynamics of these processes in real time and without disturbing the biological system is still a major methodological challenge.

12 Oct 2021

Deadly subtype of T-cell lymphoma harbors unique mutations

An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in a specific protein signaling pathway, according to a study published in the journal Blood.

7 Oct 2021

Machine learning and high-powered microscopes provide detailed snapshots of cells' inner machinery

Open any introductory biology textbook, and you'll see a familiar diagram: A blobby-looking cell filled with brightly colored structures – the inner machinery that makes the cell tick.

6 Oct 2021

First of its kind ‘living medicine’ designed to treat antibiotic-resistant bacteria on medical implants

Researchers at the Centre for Genomic Regulation and Pulmobiotics S.L have created the first 'living medicine' to treat antibiotic-resistant bacteria growing on the surfaces of medical implants. The researchers created the treatment by removing a common bacteria's ability to cause disease and repurposing it to attack harmful microbes instead.

6 Oct 2021

Researchers solve 3D structure of supramolecular protein nanoparticle using cryo-electron microscopy

Nanoparticles and nanocages are attractive materials that may be applied in color agents, catalysts, and drug delivery. For real-world use, it is necessary to produce a large number of nanoparticles of uniform size and shape, but thus far, nanoparticle formation methods using metals have been widely researched, and the formation of nanoparticles with a certain shape and size have been realized.

6 Oct 2021

New AI-based tool improves the diagnosis of breast cancer tumors

Researchers at Karolinska Institutet in Sweden have developed an AI-based tool that improves the diagnosis of breast cancer tumors and the ability to predict the risk of recurrence.

30 Sep 2021

Wiggling worms offer new clues into the potential impact of diet on Alzheimer's

Worms don't wiggle when they have Alzheimer's disease. Yet something helped worms with the disease hold onto their wiggle in Professor Jessica Tanis's lab at the University of Delaware.

29 Sep 2021

Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

Researchers from the University of Oxford and the University of Warwick have collaborated to develop a method to better understand and evaluate these pleiomorphisms.

28 Sep 2021

COVID Moonshot receives key funding to accelerate drug discovery efforts

The COVID Moonshot, a non-profit, open-science consortium of scientists from around the world dedicated to the discovery of globally affordable and easily-manufactured antiviral drugs against COVID-19 and future viral pandemics has received key funding of £8 million from Wellcome, on behalf of the Covid-19 Therapeutics Accelerator.

28 Sep 2021

New 'reporter viruses' make it easier to observe SARS-CoV-2 in real time

A version of SARS-CoV-2, the virus that causes COVID-19 disease, has been successfully modified to glow brightly in cells and animal tissues, providing a real-time way to track the spread and intensity of viral infection as it happens in animal models, researchers at Texas Biomedical Research Institute report in the journal The Proceedings of the National Academy of Sciences.

27 Sep 2021

Melanomas that metastasize to the adrenal gland are resistant to checkpoint inhibitors

Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, which are commonly used to treat melanomas, work to strengthen a patient's immune system so that it can prevent a tumor from "turning off" the ability of the immune system to fight it.

24 Sep 2021

Exploring the polymerase of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Scientists discover how mucus protein emerges to disrupt airways of individuals with lung conditions

Mucus is an essential protective layer of gel-like liquid composed largely of proteins called mucins throughout our airways. One of them, called MUC5B, is crucial for the innate defense against the various things we inhale.

23 Sep 2021

Study paves the way for development of novel delivery systems to suppress HIV

In a new study supported by the National Institutes of Health, researchers used exosomes, tiny nanoparticles capable of being taken up by cells, to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIVs' genetic material and prevented it from replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain.

21 Sep 2021

New automated computer program can accurately count micronuclei in cells

Micronuclei, which are small nucleus-like structures within cells, are commonly associated with tumors. Now, researchers from Tsukuba, Japan have developed an automated computer program that can accurately and reproducibly count these structures from microscope images, which will increase the speed and accuracy of micronuclei research.

18 Sep 2021

Microscope News and Research

New method helps to analyze proteins during dynamic processes on biological membranes

Deadly subtype of T-cell lymphoma harbors unique mutations

Machine learning and high-powered microscopes provide detailed snapshots of cells' inner machinery

First of its kind ‘living medicine’ designed to treat antibiotic-resistant bacteria on medical implants

Researchers solve 3D structure of supramolecular protein nanoparticle using cryo-electron microscopy

New AI-based tool improves the diagnosis of breast cancer tumors

Wiggling worms offer new clues into the potential impact of diet on Alzheimer's

Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

COVID Moonshot receives key funding to accelerate drug discovery efforts

New 'reporter viruses' make it easier to observe SARS-CoV-2 in real time

Melanomas that metastasize to the adrenal gland are resistant to checkpoint inhibitors

Exploring the polymerase of poxviruses at an atomic level

Scientists discover how mucus protein emerges to disrupt airways of individuals with lung conditions

Study paves the way for development of novel delivery systems to suppress HIV

New automated computer program can accurately count micronuclei in cells

Research could help design peptides to halt antibiotic-resistant bacteria

New imaging technique can change the landscape of prostate cancer detection and treatment

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

New technology offers a faster, easier and more efficient way to study gene function

UNSW Sydney scientists discover how tiny anchors help the cells to stay in place

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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