Mitochondria News and Research

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Research project focusing on membraneless organelles receives funding from Volkswagen Foundation

As part of its "Life?" project, the Volkswagen Foundation is funding a research project that is placing membraneless organelles within cells in the spotlight as a way of understanding the fundamental processes that are essential to life.

6 Sep 2021

Temperature variations could have driven the division of protocells

A simple mechanism could underlie the growth and self-replication of protocells - putative ancestors of modern living cells - suggests a study publishing September 3 in Biophysical Journal.

4 Sep 2021

Rice lab receives NIH grant to unravel DNA’s secrets

The poor bacteriophages in Yang Gao's lab are about to have a lot of bad days.

28 Aug 2021

Study unravels widespread tumor suppression mechanism that halts cancer metastasis

According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth.

26 Aug 2021

Researchers discover molecule that plays an important role in sperm motility regulation

About 120 million unintended pregnancies occurred each year between 2015 and 2019 worldwide. While there are oral contraceptives for women, the development of oral contraceptives for men has not been successful.

24 Aug 2021

Study suggests a novel therapeutic target to reverse lung fibrosis

Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, or IPF, as reported in a study published in the journal Cell Death and Differentiation.

24 Aug 2021

Stress signal from fat cells could help protect the heart from obesity’s negative consequences

A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests.

20 Aug 2021

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

Northwestern Medicine investigators have discovered that a subset of proteins in mitochondria of brain and heart cells are long-lived, supporting the long-term stability of mitochondrial complex architecture.

20 Aug 2021

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

A form of cell communication called hedgehog signaling is vital for embryonic development in mammals.

16 Aug 2021

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease.

16 Aug 2021

Link between high-fat diet, gut microbiota and cardiovascular disease revealed

A high-fat diet disrupts the biology of the gut's inner lining and its microbial communities - and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

12 Aug 2021

Study finds novel approach to attenuate mitochondrial dysfunction that drives diet-induced obesity

A team of University of California, Irvine, scientists have discovered a novel pharmacological approach to attenuate the mitochondrial dysfunction that drives diet-induced obesity.

12 Aug 2021

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

A new study from the University of Eastern Finland suggests that skin fibroblasts from frontotemporal dementia patients may be useful in investigating underlying disease mechanisms as well as in biomarker and drug research.

12 Aug 2021

Defective process in the development of RBCs may trigger lupus

The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a study led by researchers at Weill Cornell Medicine.

11 Aug 2021

Hypoxic inflammation leads to inefficient cardiac repair after heart attacks

Activation of hypoxia inducible factors (green) in macrophages (purple) that have infiltrated damaged cardiac tissue (right) in heart tissue.

10 Aug 2021

Beige fat cells mediate subcutaneous fat's brain protection from dementia

Beige is considered a calming paint color, and scientists have new evidence that beige fat has a similar impact on the brain, bringing down the inflammation associated with the more common white fat and providing protection from dementia.

10 Aug 2021

Metformin can help counter mitochondrial dysfunction in patients with type-2 diabetes

Research staff have shown that metformin, an efficient drug against type-2 diabetes, can improve the mitochondrial function in patients with this disease.

9 Aug 2021

Surfactant-coated nanoparticle applications in nanomedicine and food

A group of researchers critically review the use of surfactant-coated nanoparticles in the fields of nanomedicine and food nanotechnology.

8 Aug 2021

Researchers uncover new mitochondrial recycling pathway that may be linked to Parkinson’s disease

Scientists have long known that living cells are master recyclers, constantly breaking down old parts and building them back up into new molecular machines.

6 Aug 2021

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

5 Aug 2021

Mitochondria News and Research

Research project focusing on membraneless organelles receives funding from Volkswagen Foundation

Temperature variations could have driven the division of protocells

Rice lab receives NIH grant to unravel DNA’s secrets

Study unravels widespread tumor suppression mechanism that halts cancer metastasis

Researchers discover molecule that plays an important role in sperm motility regulation

Study suggests a novel therapeutic target to reverse lung fibrosis

Stress signal from fat cells could help protect the heart from obesity’s negative consequences

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

Link between high-fat diet, gut microbiota and cardiovascular disease revealed

Study finds novel approach to attenuate mitochondrial dysfunction that drives diet-induced obesity

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

Defective process in the development of RBCs may trigger lupus

Hypoxic inflammation leads to inefficient cardiac repair after heart attacks

Beige fat cells mediate subcutaneous fat's brain protection from dementia

Metformin can help counter mitochondrial dysfunction in patients with type-2 diabetes

Surfactant-coated nanoparticle applications in nanomedicine and food

Researchers uncover new mitochondrial recycling pathway that may be linked to Parkinson’s disease

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

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