RNA Sequencing News and Research

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Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

MicroRNAs associated with diabetes in human pancreatic islets

In a recent study published in the Proceedings of the National Academy of Sciences, researchers explored micro-ribonucleic acids (RNAs) associated with diabetes and related characteristics in human pancreatic islets.

13 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

8 Feb 2023

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Researchers at the Hong Kong University of Science and Technology developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

3 Feb 2023

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Patients with glioblastoma - the deadliest type of primary brain tumor - may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

2 Feb 2023

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Researchers evaluated the clinical and genetic characteristics of acute myeloid leukemia (AML) patients with a mutant Ikaros zinc finger protein 1 (IKZF1).

2 Feb 2023

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

A recent study posted on the bioRxiv* preprint server has longitudinally characterized the MBC repertoire and humoral response after Omicron BA.1 breakthrough infection in individuals vaccinated with the COVID-19 mRNA vaccine.

1 Feb 2023

Cancer immunotherapy does not interfere with COVID-19 immunity in vaccinated patients, study shows

Research findings published in Frontiers in Immunology show that cancer immunotherapy does not interfere with COVID-19 immunity in previously vaccinated patients.

31 Jan 2023

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Researchers investigated the CAMCI strategy as an immunotherapeutic option for inflammatory bowel disease.

31 Jan 2023

Human immunodeficiency virus and hepatitis C virus detection using ribonucleic acid sequencing among smokers

Researchers identified serological Hepatitis C virus (HCV) signatures and human immunodeficiency virus (HIV) signatures through the secondary utilization of ribonucleic acid sequencing (RNA-seq) analysis data among previous and existing smokers with or without COPD (chronic obstructive pulmonary disease).

30 Jan 2023

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

A team of investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has shown for the first time that a combination of targeted therapies with immunotherapy addresses one of the major reasons pancreatic cancer is so notoriously treatment resistant.

26 Jan 2023

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

20 Jan 2023

Research shows how Huntington’s disease affects two distinct cell populations in the striatum

In patients with Huntington's disease, neurons in a part of the brain called the striatum are among the hardest-hit.

20 Jan 2023

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Researchers evaluated immunoglobulin G (IgG) responses to coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccinations.

20 Jan 2023

RNA Sequencing News and Research

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

MicroRNAs associated with diabetes in human pancreatic islets

Casein-based diet found to protect diabetic mice against autoimmunity

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

Cancer immunotherapy does not interfere with COVID-19 immunity in vaccinated patients, study shows

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Human immunodeficiency virus and hepatitis C virus detection using ribonucleic acid sequencing among smokers

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

Research shows how Huntington’s disease affects two distinct cell populations in the striatum

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

First-ever method for analyzing RNA sequencing data genome-wide using a 'pantranscriptome'

Machine learning tools help unravel why human accelerated regions evolved so quickly

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

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