Ribonucleic Acid News and Research

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Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

In a recent study posted to the medRxiv* preprint server, researchers in Canada assessed the effectiveness of protection elicited by the fourth dose of the coronavirus disease 2019 (COVID-19) mRNA vaccine.

4 Oct 2022

Spike-specific memory B cells develop resilience to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers explored the cross-reactivity, avidity, and kinetics of memory B-cells and serum antibodies in vaccinated and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals.

4 Oct 2022

Is it safe to breastfeed after the COVID-19 mRNA vaccination?

A recent study attempts to answer the question of whether the COVID-19 vaccine is safe for lactating women who received the vaccine within six months postpartum.

3 Oct 2022

The duration of the infectious stage of individuals infected with the SARS-CoV-2 Omicron variant

Researchers demonstrated clinical features and infectivity of the currently dominant SARS-CoV-2 variant of concern Omicron, compared to Delta, the previously dominant VOC.

3 Oct 2022

Novel linear DNA SARS-CoV-2 vaccine using electroporation-aided vaccine delivery reveals lower viral shedding in ferrets

Researchers evaluated the efficacy, immunogenicity, and safety of a novel SARS-CoV-2 linear deoxyribonucleic acid vaccine in ferret models delivered using intramuscular injection and electroporation.

3 Oct 2022

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Researchers explored the in vivo efficacy of SARS-CoV-2-encoded proteins against neuromuscular degeneration associated with ribosome stalling.

3 Oct 2022

Vaccine effectiveness of a second mRNA COVID-19 vaccine booster among nursing home residents

Researchers compared the effectiveness of double booster SARS-CoV-2 mRNA vaccinations and single booster vaccinations among nursing home residents in the US.

3 Oct 2022

Vaccinated individuals infected with Omicron less likely to experience long COVID symptoms

Omicron infection and receipt of COVID-19 vaccines reduced the risk of PCC symptoms six months following infection.

2 Oct 2022

Structural analysis of monkeypox virus to guide the development of broad antiviral agents

In a new study, researchers explored the crystalline structure of the monkeypox (MPX) virus (MPXV) and the complex of VP39, a 2′-O-RNA methyltransferase (MTase) and sinefungin, a pan-MTase inhibitor.

30 Sep 2022

SARS-CoV-2 spike protein and messenger ribonucleic acid found to translocate into the nucleus

In a new study, researchers reported severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) spike (S) protein and S messenger ribonucleic acid (mRNA) nuclear co-translocation as a novel feature of SARS-CoV-2 pathogenesis.

30 Sep 2022

What is the efficacy of curcumin as a photosensitizer, prophylactic and therapeutic agent against SARS-CoV-2?

In a new study, researchers investigated the efficacy of curcumin as a blue light photosensitizing agent for photodynamic therapy (PDT), as a prophylactic agent, and as a therapeutic agent against SARS-CoV-2.

30 Sep 2022

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Researchers analyzed genomic sequences of MPXV obtained from 18 patients who contracted MPXV infection between June and July 2022.

30 Sep 2022

Pluripotent bat stem cells as a model to study novel viruses

Researchers generate induced pluripotent stem cells from bats using to establish bats as a novel in vivo model study species.

29 Sep 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

Primary vaccinations and boosters effective in reducing COVID-19 severity during Delta and Omicron predominance

In a new study, researchers analyzed COVID-19 vaccination and surveillance data to understand the effect of primary vaccinations, boosters, and prior SARS-CoV-2 infections on severe COVID-19 outcomes and subsequent infections.

29 Sep 2022

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

In a new study, researchers compared the transmissibility of novel and emerging SARS-CoV-2 variants.

29 Sep 2022

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Researchers explored the SARS-CoV-2 genome using high-throughput genome sequencing to provide novel insights into how the novel SARS-CoV-2 Omicron BA.2.3.7 variant enters and spreads among the otherwise naïve Taiwanese population.

29 Sep 2022

Study suggests B-cell responses to booster vaccines are impeded by recent SARS-CoV-2 infection

Researchers investigated whether the time of booster vaccination relative to SARS-CoV-2 infection is a crucial determinant of the elicited immune response; in particular, the antibody and B-cell responses.

29 Sep 2022

Exploring remdesivir resistance in COVID-19-infected transplant recipients

In a new study, researchers assessed the remdesivir resistance developed in coronavirus disease 2019 (COVID-19)-infected transplant recipients.

29 Sep 2022

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Researchers explored SARS-CoV-2 variants of concern/interest (VOC/VOI) kinetics and variations among non-hospitalized acute COVID-19 patients.

29 Sep 2022

Ribonucleic Acid News and Research

Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

Spike-specific memory B cells develop resilience to SARS-CoV-2

Is it safe to breastfeed after the COVID-19 mRNA vaccination?

The duration of the infectious stage of individuals infected with the SARS-CoV-2 Omicron variant

Novel linear DNA SARS-CoV-2 vaccine using electroporation-aided vaccine delivery reveals lower viral shedding in ferrets

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Vaccine effectiveness of a second mRNA COVID-19 vaccine booster among nursing home residents

Vaccinated individuals infected with Omicron less likely to experience long COVID symptoms

Structural analysis of monkeypox virus to guide the development of broad antiviral agents

SARS-CoV-2 spike protein and messenger ribonucleic acid found to translocate into the nucleus

What is the efficacy of curcumin as a photosensitizer, prophylactic and therapeutic agent against SARS-CoV-2?

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Pluripotent bat stem cells as a model to study novel viruses

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Primary vaccinations and boosters effective in reducing COVID-19 severity during Delta and Omicron predominance

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Study suggests B-cell responses to booster vaccines are impeded by recent SARS-CoV-2 infection

Exploring remdesivir resistance in COVID-19-infected transplant recipients

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

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