Clinical Trial News and Research

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FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

A Food and Drug Administration (FDA) panel created history by recommending a gene therapy for patients with cancer. In this therapy the patient’s own genes would be modified to fight the cancer cells. The patient’s cells which are thus altered to treat the cancer would thus be termed as “living drugs” as they act as soldiers to treat the cancer. These cells boost up the immune system and help the body fight the cancer.

14 Jul 2017

Scientists positively influence immune response in viral and bacterial co-infection

Researchers from Charité - Universitätsmedizin Berlin were able to positively influence the immune response in severe viral and bacterial co-infection.

13 Jul 2017

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia.

13 Jul 2017

FDA advisory committee recommends Novartis' CAR-T therapy for young leukemia patients

Today the FDA's Oncologic Drugs Advisory Committee, an independent panel of experts, voted unanimously to recommend to the FDA approval of Novartis' experimental CAR-T therapy called Tisagenlecleucel, also known as CTL019.

13 Jul 2017

Bone metastasis-targeting drug shows potential as new therapeutic strategy for osteosarcoma

The treatment of osteosarcoma, the most common tumor of bone, is challenging. A study led by The University of Texas MD Anderson Cancer Center found a drug known as bone metastasis-targeting peptidomimetic (BMTP-11) has potential as a new therapeutic strategy for this devastating illness.

13 Jul 2017

ERYTECH partners with Queen’s University to advance its product candidate for treating arginase-1 deficiency

ERYTECH Pharma, a French clinical-stage biopharmaceutical company developing innovative therapies for rare forms of cancer and orphan diseases, today announced that it has entered into a research collaboration with Queen's University in Canada to advance the preclinical development of ERYTECH's eryminase program specifically for the treatment of arginase-1 deficiency, a rare and severe metabolic disorder related to arginine metabolism.

12 Jul 2017

Novel therapy rapidly and effectively reverses effect of oral blood thinner

At least 28 million prescriptions for blood thinners are filled by pharmacists yearly for the irregular heartbeat of atrial fibrillation, deep vein thrombosis, and other indications, according to the Department of Health and Human Services.

11 Jul 2017

BetterYou magnesium flakes shown to ease restless legs syndrome

An Essex mum of three suffering from restless legs syndrome (RLS) can finally share a bed with her husband again thanks to a natural Magnesium Flake remedy, which featured on the ‘Secrets of Sleep’ (More4, 5 July).

From BetterYou Ltd 10 Jul 2017

Medtech, biotech and pharmaceuticals in Australia

Australia is an acknowledged world leader in the medical technology, biotechnology and pharmaceutical (MTP) sector due to its vibrant ecosystem of start-ups and established companies and thriving research environment.

10 Jul 2017

Novel therapy decreases incidence of bleeding by 87% in hemophilia A patients with inhibitors

An international team of hematologists including Guy Young, MD, of Children's Hospital Los Angeles, has found that in patients with hemophilia A with inhibitors, a novel therapy called emicizumab, decreases incidence of bleeding episodes by 87%.

10 Jul 2017

Study compares long-term outcomes of bariatric surgery with medical, lifestyle management of diabetes

A team of Cleveland Clinic researchers is leading a first-of-its-kind multicenter clinical trial to assess the long-term outcomes of bariatric/metabolic surgery compared to medical and lifestyle therapy for treating Type 2 diabetes.

10 Jul 2017

Study: Mindfulness-based therapy lowers stress and blood sugar in overweight, obese women

In a randomized clinical trial of women who were overweight or obese, mindfulness-based stress reduction increased mindfulness and decreased stress compared with health education. In addition, fasting blood sugar levels decreased within the MBSR group, but not within the health education group.

7 Jul 2017

Entasis and GARDP partner to develop oral antibiotic for treatment of drug-resistant gonorrhea

Zoliflodacin, a novel first-in-class oral antibiotic and one of the only treatments in development to address the rapidly-growing threat of drug-resistant gonorrhea will enter pivotal trials, thanks to a new partnership between the not-for-profit Global Antibiotic Research and Development Partnership and Entasis Therapeutics.

7 Jul 2017

Researchers receive $8.6 million NIH grant for efforts to improve lung transplantation

Researchers at the University of Virginia School of Medicine have received more than $8.6 million in federal grants to support efforts that could dramatically increase the number of lungs available for transplant – and then save the lives of the people who receive them.

6 Jul 2017

Clinical trial shows anti-inflammatory benefits from taking high doses of vitamin D after sunburn

High doses of vitamin D taken one hour after sunburn significantly reduce skin redness, swelling, and inflammation, according to double-blinded, placebo-controlled clinical trial out of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center.

6 Jul 2017

Combination therapy may lead to new standard of care for kidney cancer patients

Combination therapy with two immunotherapy drugs produces an unprecedented doubling of response rates from 20 percent to 40 percent, new study shows.

6 Jul 2017

Anti-asthma drug shows blood glucose improvement among some patients with type 2 diabetes

After 12 weeks of taking an anti-asthma drug, a subset of patients with type 2 diabetes showed a clinically significant reduction in blood glucose during a randomized, double blind, placebo-controlled clinical trial, report University of California San Diego School of Medicine and University of Michigan researchers.

5 Jul 2017

Reducing DVT and leg ulcers through personalized compression socks

Professor Charles McCollum, who heads up the vascular studies unit, is a research vascular surgeon, and he developed four-layer bandaging technique, which is the gold standard treatment for healing up leg ulcers by compression.

5 Jul 2017

UC scientists develop new computerized tool to promote shared decision-making with CF patients

Physician-researchers at the University of Cincinnati have developed a computerized decision-making model to promote shared decision-making with cystic fibrosis patients.

4 Jul 2017

Google’s DeepMind project and Royal Free Trust breach patient privacy laws

In a breach of patient trust, a British hospital shared the personal information of around 1.6 million patients with Google's DeepMind. This was reported by a British data protection watchdog - Information Commissioner's Office (ICO) yesterday, creating a stir. The deal between the Royal Free NHS Trust and Google’s DeepMind first became known to the public in February 2016.

3 Jul 2017

Clinical Trial News and Research

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

Scientists positively influence immune response in viral and bacterial co-infection

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

FDA advisory committee recommends Novartis' CAR-T therapy for young leukemia patients

Bone metastasis-targeting drug shows potential as new therapeutic strategy for osteosarcoma

ERYTECH partners with Queen’s University to advance its product candidate for treating arginase-1 deficiency

Novel therapy rapidly and effectively reverses effect of oral blood thinner

BetterYou magnesium flakes shown to ease restless legs syndrome

Medtech, biotech and pharmaceuticals in Australia

Novel therapy decreases incidence of bleeding by 87% in hemophilia A patients with inhibitors

Study compares long-term outcomes of bariatric surgery with medical, lifestyle management of diabetes

Study: Mindfulness-based therapy lowers stress and blood sugar in overweight, obese women

Entasis and GARDP partner to develop oral antibiotic for treatment of drug-resistant gonorrhea

Researchers receive $8.6 million NIH grant for efforts to improve lung transplantation

Clinical trial shows anti-inflammatory benefits from taking high doses of vitamin D after sunburn

Combination therapy may lead to new standard of care for kidney cancer patients

Anti-asthma drug shows blood glucose improvement among some patients with type 2 diabetes

Reducing DVT and leg ulcers through personalized compression socks

UC scientists develop new computerized tool to promote shared decision-making with CF patients

Google’s DeepMind project and Royal Free Trust breach patient privacy laws

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