Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Lilly, Boehringer Ingelheim announce results from linagliptin Phase III trial on T2D

Boehringer Ingelheim and Eli Lilly and Company presented results from a randomised Phase III clinical trial and a post-hoc analysis for linagliptin at ADA.

11 Jun 2012

Genetic influence on postmenopausal bone loss falls with age

The effect of genetics on bone loss rates in postmenopausal women reduces until the age of 65 years, after which time its influence disappears completely, according to results from a twin-based study.

8 Jun 2012

Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD

Amgen today announced top-line results of the Phase 3 EVOLVE (EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events) trial, which evaluated Sensipar/Mimpara (cinacalcet) for the reduction of the risk of mortality and cardiovascular (CV) events among 3,883 patients with secondary hyperparathyroidism (HPT) and chronic kidney disease (CKD) receiving dialysis.

8 Jun 2012

Study packs powerful one-two punch in the fight against heart failure

A new study in the journal Circulation packs a powerful one-two punch in the fight against heart failure. The leading blow: Identification of a unique alliance of proteins that plays a major role in the development of the disease. The second but equally powerful hit: Drugs that interfere with this axis already exist.

8 Jun 2012

Patients over 45 years with history of early menopause 50% less likely to develop severe RA

A new study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, shows that early menopause predicts a milder form of rheumatoid arthritis (RA).

8 Jun 2012

Tp53 genetic mutation may play an important role in prostate cancer

A team of UC Davis investigators has found that a genetic mutation may play an important role in the development of prostate cancer. The mutation of the so-called p53 (or Tp53) gene was previously implicated in late disease progression, but until now has never been shown to act as an initiating factor. The findings may open new avenues for diagnosing and treating the disease.

8 Jun 2012

BD, JDRF partner to accelerate development of glucose-sensing technology for T1D

JDRF and BD today announced an extension of their existing collaboration focused on Type 1 diabetes (T1D) to accelerate the development of BD's proprietary glucose-sensing technology which has shown promise in providing very accurate and reliable continuous glucose information.

From BD (Becton, Dickinson and Company) 8 Jun 2012

Researchers identify brain receptor that appears to play a central role in regulating appetite

Researchers at Columbia University Medical Center (CUMC) have identified a brain receptor that appears to play a central role in regulating appetite. The findings, published today in the online edition of Cell, could lead to new drugs for preventing or treating obesity.

8 Jun 2012

Aldosteronism linked to poor bone health

Primary aldosteronism is associated with low bone mass, increased prevalence of osteoporosis, and vertebral fractures, Italian research shows.

7 Jun 2012

Regular meditation could reduce risk of cardiovascular disease among teens

Regular meditation could decrease the risk of developing cardiovascular disease in teens who are most at risk, according to Georgia Health Sciences University researchers.

7 Jun 2012

Dentists explore how psychological factors affect oral health

What does mental health have to do with dental health? Quite a bit, according to Richard Heyman, PhD, and Amy Smith Slep, PhD, psychologists who joined the New York University College of Dentistry (NYUCD) in July 2011.

7 Jun 2012

Split-course RT valuable after hormone-resistant prostate cancer relapse

A split course of high-dose radiotherapy in men with progressive, hormone-refractory prostate cancer is effective and has an acceptable toxicity profile, report Australian researchers.

6 Jun 2012

Phase III study of AFOLIA, a biosimilar r-FSH meets its endpoint

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6 Jun 2012

New tool helps researchers to better understand Type 2 human diabetes

With Type 2 human diabetes climbing at alarming rates in the United States, researchers are seeking treatments for the disease, which has been linked to obesity and poor diet. Now biologists at Southern Methodist University, Dallas, report they have developed a new tool that will help researchers better understand this deadly disease.

6 Jun 2012

Abbott commences elagolix Phase 3 trial in endometriosis

Abbott, in cooperation with Neurocrine Biosciences, Inc., today announced the initiation of a pivotal Phase 3 clinical trial designed to evaluate the safety and efficacy of elagolix in female patients with endometriosis.

6 Jun 2012

Brains of anxious girls work much harder than those of boys

In a discovery that could help in the identification and treatment of anxiety disorders, Michigan State University scientists say the brains of anxious girls work much harder than those of boys.

6 Jun 2012

Esperance presents results from EP-100 Phase 1 study on solid tumors at ASCO annual meeting

Esperance Pharmaceuticals presented its Phase 1 study of EP-100, a novel targeted membrane‐disrupting peptide (tMDP) in advanced solid tumors at the American Society for Clinical Oncology (ASCO) Annual Meeting in Chicago, Illinois.

5 Jun 2012

High doses of ginseng more effectively reduce cancer-related fatigue in patients

High doses of the herb American ginseng (Panax quinquefolius) over two months reduced cancer-related fatigue in patients more effectively than a placebo, a Mayo Clinic-led study found. Sixty percent of patients studied had breast cancer. The findings are being presented at the American Society of Clinical Oncology's annual meeting.

5 Jun 2012

Androgen receptor an additional hormonal target in many breast cancers

Many breast cancers depend on hormones including estrogen or progesterone for their survival and proliferation. Eight years of lab work at the University of Colorado Cancer Center and elsewhere suggest that the androgen (AR) receptor is an additional hormonal target in many breast cancers. Block AR+ breast cancer's ability to access androgen and you block the cancer's ability to survive.

5 Jun 2012

Many men with metastatic prostate cancer live longer on continuous hormone therapy

Many men with metastatic, hormone-sensitive prostate cancer live longer on continuous androgen-deprivation therapy (also known as hormone therapy) than on intermittent therapy, according to a seventeen-year study led by SWOG, a cancer research cooperative group funded by the National Cancer Institute (NCI).

4 Jun 2012

Hormone News and Research

Further Reading

Lilly, Boehringer Ingelheim announce results from linagliptin Phase III trial on T2D

Genetic influence on postmenopausal bone loss falls with age

Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD

Study packs powerful one-two punch in the fight against heart failure

Patients over 45 years with history of early menopause 50% less likely to develop severe RA

Tp53 genetic mutation may play an important role in prostate cancer

BD, JDRF partner to accelerate development of glucose-sensing technology for T1D

Researchers identify brain receptor that appears to play a central role in regulating appetite

Aldosteronism linked to poor bone health

Regular meditation could reduce risk of cardiovascular disease among teens

Dentists explore how psychological factors affect oral health

Split-course RT valuable after hormone-resistant prostate cancer relapse

Phase III study of AFOLIA, a biosimilar r-FSH meets its endpoint

New tool helps researchers to better understand Type 2 human diabetes

Abbott commences elagolix Phase 3 trial in endometriosis

Brains of anxious girls work much harder than those of boys

Esperance presents results from EP-100 Phase 1 study on solid tumors at ASCO annual meeting

High doses of ginseng more effectively reduce cancer-related fatigue in patients

Androgen receptor an additional hormonal target in many breast cancers

Many men with metastatic prostate cancer live longer on continuous hormone therapy

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